N/A N=214 Hypotension Prediction Index for Blood Pressure Management
Intraoperative Hypotension
Primary: Time- Weighted Average (TWA) MAP Under a Threshold of 65 mmHg. — 0.14; 0.14 mmHg — p=0.757
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=11 Platelet Rich Plasma Injection in Pilon Fractures
Fracture
Primary: Intra-articular Inflammatory Biomarkers at the Time of Definitive Fixation — 54.89; 163.01; 2479.17; 2511.32 pg/ml
Phase 1 N=19 Single Dose Crossover Study to Compare the Respiratory Drive After Administration of Belbuca, Oxycodone and Placebo.
Respiratory Depression
Primary: Respiratory Drive — 23957.34; 22460.95; 23626.79; 21577.15 mL/min
Phase 1 N=44 A Comparative Study of New Formulation and Approved Formulation for Levothyroxine in Healthy Volunteers
Healthy
Primary: Maximum Serum Concentration in Pre Dose Corrected Data (Cmax[aj]) of Levothyroxine (T4) — 67.24; 66.44 nanogram per milliliter (ng/mL)
N/A N=18 LC Bead LUMI for Prostatic Artery Embolization
BPH
Primary: Mean Change in IPSS Score — -11.4 units on a scale
Phase 3 N=100 A Clinical Trial to Assess the SYNERGY 48 mm Stent System for the Treatment of Atherosclerotic Lesion(s)
Coronary Artery Disease
Primary: Target Lesion Failure Rate at 12-months — 4 percentage of participants
N/A N=104 Investigation of Synbiotic Treatment in NAFLD
Non-Alcoholic Fatty Liver Disease
Primary: Change in Liver Fat — -3.8; -6.0 percentage of liver fat — p==0.05
Phase 4 N=32 Fibrinolysis Compared to Thoracoscopy for Pleural Infection
Pleural Infection · Empyema · Pleural Diseases
Primary: Duration of Hospital Stay After Intervention — 4; 2 days
Phase 4 N=468 A Study to Evaluate Cooling Sensation of an Allergy Product in Adults With a History of Allergies
Allergic Rhinitis
Primary: Proportion of Participants With Agreement of Perception of Cooling Sensation — 0.99 Proportion of participants
N/A N=10 Study for the RevLite Laser System for Facial Solar Lentigines
Facial Solar Lentigines
Primary: Photographic Evaluation Using the Blinded Global Aesthetic Improvement Scale — 0; 1; 3; 3 Participants
Phase 3 N=602 Efficacy, Safety and Dose-Response Study Followed by Open-Label Study of Lofexidine Treatment of Opioid Withdrawal
Opioid Dependence · Acute Opioid Withdrawal Syndrome
Primary: Difference Between the Overall Means From Short Opiate Withdrawal Scale of Gossop (SOWS-Gossop) Scores — 7.8; 7.6; 9.4; 10.2 score on a scale — p=0.0166
N/A N=411 Evaluation of Moderate to Severe Influenza Outcomes in Children
Influenza · Otitis Media · Lower Resp Tract Infection
Primary: Hospitalization — 26; 2 Participants
Phase 2 N=68 Study to Investigate Whether AFQ056 Reduces Cocaine Use in Patients Diagnosed With Cocaine Use Disorder (CUD)
Cocaine-related Disorder
Primary: Proportion of Cocaine Use Days — 0.122; 0.209 cocaine use days — p== 0.021
Phase 4 N=45 Low Dose Ketamine (LDK) Versus Morphine for Acute Pain Control in the Emergency Department
Abdomen, Acute · Other Acute Pain · Flank Pain
Primary: Maximal Change in Numerical Rating Scale (NRS) Pain Score From Baseline NRS Pain Score — -4.9; -5 NRS pain scale score
N/A N=32 Transversus Abdominis Plane Block in Children Undergoing Open Pyeloplasty Surgery
Anesthesia
Primary: Requirement for Morphine Post-surgery. — 13; 6 Participants