6,678 trials
Cushing's Disease · Acromegaly
Primary: Change in HbA1c From Randomization to Approximately 16 Weeks — -0.12; 0.26; 0.33; 0.45 Hba1c percentage
Heart Failure
Primary: Median Urine Output at 24 Hours Post Randomization — 2910; 3150 mL
Airway Control · Anesthesia · Intubation
Primary: SOFA Score — 6.5; 7 units on a scale
Preterm Birth · Child Development
Primary: Erythrocyte Fatty Acid Levels — -2.1; 0.6; 2.0; -0.2 nmol/mL — p=<0.001
Pain
Primary: Patients With Clinical Signs of Respiratory Depression or Sub Clinical Respiratory Depressions Measured by Capnography and Pulse Oximetry. — 22; 21 Participants
Bronchopulmonary Dysplasia · Very Low Birth Weight
Primary: Change in Respiratory Resistance — 0.011; 0.006; 0.014 cm h2o/mL/sec
Hypertension, Pregnancy-Induced · Pre-eclampsia
Primary: Difference in Systolic Blood Pressure (SBP) — 131.8; 132.0; 129.1; 129.1 mmHg
Pregnancy
Primary: Percentage of Participants With Injection-site Reactions Post Tdap and IIV4 Administration — 47.5; 48.6; 37.5; 45.9 percentage of participants
Menorrhagia · Metrorrhagia · Medicated Intrauterine Devices
Primary: Number of Bleeding and Spotting Days — 16.8; 12.0 days
Femoracetabular Impingement · Pain, Postoperative
Primary: Opioid Consumption in the Acute Postoperative Period — 57.3; 56.0; 37.0; 40.1 milligram morphine equivalents (mEq)
Depression
Primary: Response to Medications as Assessed by Change in Score on Modified MDRS Scale From Baseline to End of Study Period — 3.5; 12.5 units on a scale — p=0.03
Dental Plaque · Gingivitis
Primary: Dental Plaque Score — 3.53; 3.55; 3.59 units on a scale — p=0.919
Pelvic Organ Prolapse
Primary: Number of Participants Experiencing Urinary Tract Infection Within 6 Weeks of Surgery — 13; 13 Participants — p=0.97
Epilepsy
Primary: AUC — 79640; 81653 ng*hr/ml
Anesthesia
Primary: R-methadone Plasma AUC 0-96hr/Dose — 228; 189; 205; 0 (ng * hr-1 * ml-1 * mg-1 — p=<0.05