N/A N=273 Treatment Outcomes for Ankle Arthritis
Osteoarthritis
Primary: Musculoskeletal Functional Assessment (MFA) — -12.5; -15.0 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=50 Agility LP Ankle Arthroplasty Outcomes
Rheumatoid Arthritis of Ankle · Osteoarthritis of Ankle · Traumatic Arthritis of Ankle
Primary: Assessment of Functional Outcomes Following Agility LP Ankle Replacement — 37.67; 37.07 Degrees
Phase 4 N=14 Anesthesia for Pain After Ankle Fracture Surgery
Chronic Pain · Ankle Fracture Surgery · Regional Anesthesia
Primary: Pain Score at 12 Months - Experimental Group vs. Control Group — 36.33; 44.00 units on a scale — p=0.1269
N/A N=80 Saphenous Nerve Block for Foot and Ankle Surgery
Saphenous Nerve Block
Primary: Block Success — 18; 22 participants — p=0.25
Phase 3 N=30 Effects of CHONDRON (Autologous Chondrocytes) With Ankle Cartilage Defect
Articular Cartilage Defects of Ankle Joint
Primary: Average Change From Baseline in American Orthopedic Foot and Ankle Society(AOFAS) at 12 Months Post-surgery — 16.93 scores
Phase 4 N=100 Efficacy of Tranexamic Acid in Foot and Ankle Surgeries
Foot and Ankle Surgeries · Bunion
Primary: Total Estimated Blood Loss — 40.41; 18.75 ml
N/A N=11 Platelet Rich Plasma Injection in Pilon Fractures
Fracture
Primary: Intra-articular Inflammatory Biomarkers at the Time of Definitive Fixation — 54.89; 163.01; 2479.17; 2511.32 pg/ml
N/A N=148 A Longitudinal Outcomes Study of the Subchondroplasty® Procedure in the Foot/Ankle
Insufficiency Fractures · Stress Fracture · Stress Fracture, Ankle, Foot and Toes
Primary: Foot Function Index-Revised (FFI-R) Short Form Score at 24 Months — 42.8; 43.0; 39.6 Percentage scale
N/A N=111 Brace Versus Casting in Pediatric Low Risk Ankle Fractures
Ankle Fracture
Primary: Functional Outcome as Measured by the Activities Scale for Kids at 4 Weeks From the Time of the Initial Injury — 85.3; 91.3 percentage of questions
N/A N=233 A Multicenter Randomized Trial Comparing Antiglide and Lateral Plate Fixation in Ankle Fractures
Ankle Injuries
Primary: Percentage of Nonpalpable Hardware — 71; 55; 64; 66 percentage of participants
Phase 4 N=100 Efficacy of Multimodal Periarticular Injections in Operatively Treated Ankle Fractures
Pain, Postoperative · Ankle Fractures
Primary: Change in Post-operative Visual Analog Pain Scores (VAS) — 42; 52; 41; 50 0 to 100 score on a scale
N/A N=21 Internal Brace Augmented Anterior Inferior Tibiofibular Ligament Repair: Post-operative Syndesmotic Volumes.
Syndesmotic Injuries · Ligament Rupture · Bimalleolar Fractures
Primary: Syndesmotic Volumetric Ratio — 1.2; 1.1 Volumetric Ratio
N/A N=22 Iterative Design of Custom Dynamic Orthoses to Reduce Articular Contact Stress
Ankle Fractures · Post-traumatic Osteoarthritis · Osteoarthritis Ankle
Primary: Joint Contact Stress Time Exposure (Model Estimated) — 4.44; 3.97; 4.08; 4.25 MPa-s/gait cycle
N/A N=25 Study of Cingal® for Symptomatic Relief of Osteoarthritis of Ankle Joint
Osteoarthritis, Ankle
Primary: Numerical Rating Scale (NRS) Pain on Walking — -3.84 units on a scale — p=<0.0001
N/A N=98 Prospective Randomized Evaluation of a Two and Three Piece Total Ankle Replacement
Ankle Osteoarthritis
Primary: Pain Following a Total Ankle Replacement as Measured by the Visual Analog Scale (VAS) for Pain — 67.0; 71.3; 16.7; 18.6 mm — p=0.29
N/A N=11 Do Rocker Bottom Shoes and Ankle-Foot Orthoses Reduce Pain and Improve Mobility for Ankle Osteoarthritis Patients
Ankle Osteoarthritis · Healthy Ankles
Primary: Daily Step Count (# Steps) — 3453; 2399; 3453; 2745 steps
N/A N=9 Computed Tomography for Evaluating Supination-external Rotation Type Ankle Fractures
Supination-external Rotation Ankle Fractures
Primary: Medial Clear Space Distance in the Ankle Joint — 1.41 mm
Phase 4 N=20 MIDCAB (Mid-Calf Block) for Foot Surgery
Ankle Surgery · Foot Surgery
Primary: Block Duration — 18.2 hours
N/A N=242 Dilute Betadine Soak and Scrub for Foot and Ankle Surgery
Postoperative Infection · Postoperative Complications
Primary: Bacterial Culture Growth — 32; 33 Participants
Phase 4 N=36 Spinal Versus General Anesthesia With Popliteal and Adductor Canal Blocks for Ambulatory Foot and Ankle Surgery.
Nerve Block · General Anesthesia · Spinal Anesthesia
Primary: Time Until Patient is Ready for Discharge From Post-Anesthesia Care Unit (PACU) to Home. — 81; 43.5 Minutes
N/A N=34 Ankle Robotics Training After Stroke
Seated Treadmill Training · Treadmill Locomotor-based Training · Treadmill Only
Primary: Self-selected Floor Walking Velocity Change From Baseline to Post-training and Retention — 56.0; 55.5; 50.9; 56.1 cm/sec — p=< 0.01
N/A N=21 Lateral Ankle Sprain and Platelet Rich Plasma
Ankle Injuries
Primary: American Orthopedic Foot and Ankle Society Ankle-Hindfoot Scale (AOFAS) — 97.8; 98.5 units on a scale
N/A N=40 Cryoneurolysis for Improvements in Pain, ADL and QOL in Patients With Ankle Osteoarthritis
Ankle Osteoarthritis
Primary: FAOS - PAIN — 20.8 score on a scale
N/A N=30 Assessment of Ability of 3D Fluorscopy in Aiding Accurate Syndesmotic Reduction Following Traumatic Ankle Injury
Displaced Ankle Fractures
Primary: Number of Participants for Which the Surgeon Changed Reduction of Syndesmotic Reduction Because of Information Provided by 3D Fluoroscopy — 14 Participants
N/A N=48 Prospective Subtalar, Double, or Triple Arthrodesis Study With CCS Screws
Post-traumatic Osteoarthritis, Unspecified Ankle and Foot · Localized, Primary Osteoarthritis of the Ankle and/or Foot
Primary: Number of Participants With Intraoperative Complications — 0 Participants
N/A N=56 AMPLEX Ankle Fusion and Hindfoot
Arthrodesis Surgery Involving the Hindfoot or Ankle
Primary: Proportion of Subjects Who Met All Five Criteria for Subject Performance Composite (SPC) Endpoint — 79.5; 35.3 percentage of subjects
Phase 3 N=93 Ropivacaine Versus Bupivacaine as Preemptive Analgesia in Surgical Site in Ankle Fracture Patients
Ankle Fractures · Pain, Postoperative · Local Infiltration
Primary: VAS — 2.81; 2.13; 3.52; 4.52 units on a scale (VAS)
N/A N=25 MONOVISC for Ankle Joint Pain Relief Due to Osteoarthritis
Osteoarthritis Ankle
Primary: Numerical Rating Scale (NRS) Pain on Walking — -3.00 score on a scale — p=<0.0001
N/A N=377 Predicting Ankle Injury Through Clinical Functional Measures in Adolescent Athletes
Other Instability, Ankle and Foot
Primary: Dynamic Balance: (Star Excursion Balance Test) — 72.3; 78.0 % of leg length
N/A N=107 Study of an Orthotic Designed to Equalize Leg Lengths for Patients With Injuries Managed in Walking Boots
Joint Pain · Trouble Balancing
Primary: Patient Reported Balance — 3.0; 2.1 units on a scale