N/A N=258 Navigation Endoscopy to Reach Indeterminate Lung Nodules Versus Trans-Thoracic Needle Aspiration
Lung Nodule
Primary: Diagnostic Accuracy — 94; 81 Participants — p=0.003
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=10 CrYobiopsy With Radial UltraSound Guidance
Pulmonary Disease
Primary: Time to Achieve Hemostasis After Obtaining Cryobiopsy — 146.55; 132.25 seconds — p=0.7878
N/A N=20 EBUS-Miniforceps Biopsy Specimen Acquisition for PD-L1 Testing in Nonsmall Cell Lung Cancer
Non Small Cell Lung Cancer · NSCLC
Primary: Feasibility of Utilizing Endobronchial Ultrasound Guided Miniforceps as Assessed by the Number of Participants From Whom Adequate Amounts of Tissue to Perform PD-L1…
N/A N=24 Pilot Study of Navigational Bronchoscopy and Transthoracic Needle Biopsy
Peripheral Pulmonary Nodules
Primary: Feasibility — 24 participants
N/A N=30 InvestigatioN of a Smart Probe for Lung lEsion Characterization Using Impedance Technology
Lung Cancer
Primary: The Ability of BioSpy System to Acquire Electrophysiological Measurements in the Relevant Tissues During Bronchoscopic Biopsy. — 26 Participants
N/A N=51 Safety of a Sheath Cryoprobe Bronchoscopic Transbronchial Biopsy Technique
Lung Diseases
Primary: Number of Participants With Serious Adverse Events — 0 Participants
N/A N=55 Robotic Bronchoscopy for Peripheral Pulmonary Lesions
Lung; Node
Primary: Number of Participants With Device or Procedure Related Adverse Events — 2 Participants
N/A N=30 Feasibility of Performing Peripheral Pulmonary Lesion Biopsy Using Robotic Bronchoscopy-Guided Cryoprobe
Bronchi--Diseases · Lung Diseases, Obstructive · Lesions Mass
Primary: Ability to Successfully Obtain Sample — 123; 130 tissue samples
Phase 3 N=454 Effect of Autologous Blood Patch Injection Versus BioSentry Hydrogel Tract Plug in the Reduction of Pneumothorax Risk Following Lung Biopsy Procedures
Lung Biopsy
Primary: the Rate of Pneumothorax — 42; 60; 184; 168 Participants
Phase 3 N=339 Bio-Seal Biopsy Track Plug for Reducing Pneumothorax Rates Post Lung Biopsy Procedure
Pneumothorax
Primary: Incidence Rate of Treatment Success — 126; 94 participants
N/A N=339 Ultrathin Bronchoscope and Radial Endobronchial Ultrasound (R-EBUS) With Fluoroscopy Versus Standard Fiberoptic Bronchoscopy (FB) (P00029233 )
Pulmonary Lesions · Pulmonary Nodules · Pulmonary Mass
Primary: Diagnostic Yield of Procedures; Number of Positive Diagnosis of Pulmonary Lesions — 51; 62; 58; 51 participants
Phase 2 N=25 Percutaneous Image Guided Video-Assisted Thoracic Surgery (VATS) Resection of Lung Lesions
Lung Cancer
Primary: Number of Participants With Treatment-related Adverse Events as Assessed by CTCAE v4.0 — 1 Participants
N/A N=200 Lung Ultrasonography vs Fiberoptic Bronchoscopy for Aiding Lung Collapse in Patient Using Double Lumen Tube
Lung Diseases · Ultrasonography · Fiberoptic Bronchoscopy
Primary: Number of Patients of Lung Collapse in Ultrasonography and Fiberoptic Bronchoscopy — 89; 83 Participants
Early Phase 1 N=17 Characterization of Tissue-Specific Immune Responses to Bronchoscopic Instillation of Mycobacterial Antigens Into the Human Lung
Healthy · Latent Tuberculosis Infection (LTBI)
Primary: Median Difference in CD4 Cell Response to Intrabronchial Instillation of Tuberculin Purified Protein Derivative (PPD) — 5.26; 0.725; 29.9; 2.92 % Antigen Specific T…
N/A N=105 Piloting a Virtual Navigation (VN) System for Bronchoscopic Lung Nodule Sampling
Lung Cancer
Primary: Safety Measurement — 0; 0; 0; 0 Adverse events
N/A N=25 EPIONE Guided Lung Evaluation
Lung Cancer
Primary: Feasibility of the Device — 26 Number of targets reached
Early Phase 1 N=21 Bronchoscopic Cryo-Immunotherapy of Lung Cancer
Advanced Non-small Cell Lung Cancer
Primary: Percentage of Successful Performances Among Patients in Whom BCI is Attempted — 100 Percentage of participants
N/A N=39 Thoracoscopic Sentinel Lymph Node Biopsy in Patients With Stage I or Stage II Breast Cancer
Breast Cancer
Primary: Success Rate in Removing Sentinel Lymph Nodes by Thoracoscopy — 31 participants
N/A N=6 Pathologic and Immunologic Response After Ablative Radiation in Lung Cancer
Non-small Cell Lung Cancer Stage I
Primary: Examine the T-cell Receptor Profile Changes Induced in the Tumor After SABR
N/A N=49 FOB in HSCT and Leukemia Patients With Acute Respiratory Symptoms and Pulmonary Infiltrates
Pulmonary Infiltrate New
Primary: Number of Patients With Positive Culture or Molecular Results After Brochoscopy — 40 participants
Early Phase 1 N=35 Bronchoscopy in Determining the Effect of E-Cigarette Smoking on Biomarkers in the Lungs
Cigarette Smoker · Current Every Day Smoker
Primary: Changes in Cytokines — 0.2473; -0.04988; -0.1137; -0.05875 pg/ml
N/A N=61 Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration Using a 22 vs 25-Gauge Needle
Malignant Neoplasm of Respiratory and Intrathoracic Organ Carcinoma · Lung Cancer
Primary: Percentage of Lymph Nodes With Adequate Samples — 79; 78.5 Percentage of Lymph Nodes
Phase 3 N=158 Trial to Assess the Anti-inflammatory Effects of Roflumilast in Chronic Obstructive Pulmonary Disease
COPD · Chronic Obstructive Pulmonary Disease
Primary: Number of CD8+ Inflammatory Cells in Bronchial Biopsy Tissue. — 442.4; 427.1 CD8+ cells count
N/A N=26 Accuracy of Spybite Forceps When Compared to Conventional Sampling Methods
Accuracy of Tissue Diagnosis · Bile Duct Stricture · Pancreatic Duct Stricture
Primary: Percentage of Participants With Accurate Diagnoses of Cancer — 38.5; 53.9; 84.6 percentage of accurate diagnoses
N/A N=21 Endoscopic Ultrasound(EUS)-Guided TRUCUT Biopsy (EUS-TCB) of Suspected Nonalcoholic Fatty Liver Disease(NAFLD.)
Non-alcoholic Fatty Liver Disease · Nonalcoholic Steatohepatitis
Primary: Median Total Specimen Length — 8; 14; 8; 11.5 mm
N/A N=40 Lung Collapse With Bronchial Blocker
Video-assisted Thoracoscopic Surgery · Lung Isolation Device · One-lung Ventilation
Primary: Time to Obtain Complete Lung Collapse — 47.8; 32.5 minutes
N/A N=86 ENB-GS-TBLB for the Diagnosis of PPLs
Lung Cancer
Primary: The Difference of Diagnostic Value of ENB-GS-TBLB as Compared to GS-TBLB — 34; 25; 5; 16 participants — p=0.019
Phase 3 N=66 Prophylactic Topical Epinephrine to Reduce Bleeding in Transbronchial Lung Biopsies
Lung Transplant; Complications, Mechanical · Lung Transplant; Complications · Bleeding
Primary: Intra-procedural Hemorrhage Grading by the Performing Bronchoscopist — 4; 13; 11; 24 Procedures
N/A N=25 Sputum Labeling Utilizing Synthetic Meso-Tetra (4-Carboxyphenyl) Porphine (TCPP) for Detection of Lung Cancer
Lung Cancer
Primary: Number of Red Fluorescent [i.e., Cancer] Cells (RFCs) in Sputum From Healthy Participants — 0 number of RFCs per participant
N/A N=207 Autologous Stem Cell Treatment for Chronic Lung Disease Study
COPD · Interstitial Lung Disease
Primary: Change in FEV1 From Baseline Among COPD Patients — 12.8 percentage of change in FEV1