N/A N=21 Vacuum-Assisted Dressings (V-AD) in the Management of Open Chest Wounds
Open Chest Wounds
Primary: Duration of Negative Pressure Wound Therapy (NWPT) — 8 Days
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=109 Prospective Evaluation of 14F Thal Tube vs 28 French Chest Tube for Hemothorax and Use of Maximum Barrier Precautions
Hemothorax · Hemopneumothorax; Traumatic · Empyema
Primary: Number of Participants With Retained Hemothorax Following Initial Chest Tube Placement Requiring Intervention — 51; 48 Number of Participants — p=0.036
N/A N=1,869 Negative Pressure Wound Therapy for Prevention of Poststernotomy Infection
Surgical Wound Infection
Primary: Wound Infection After Open Heart Surgery — 4; 17 Participants — p=0.55
N/A N=140 Evaluation of Primary Plating in Sternotomy Patients for Osteosynthesis and Pain
Sternal Wound Infection · Sternal Non-union · Pain
Primary: CT Scan Evaluation of Sternal Bone Healing — 0.9; 1.7; 2.2; 3.2 units on a scale — p=0.003
N/A N=63 Vacuum Assisted Closure as a Treatment for Open Fractures
Orthopaedic Traumatic Open Fractures
Primary: Healing of Orthopaedic Trauma Open Fractures — 3.2; 4.0 use days
N/A N=34 Comparative Evaluation of External Chest Wall Fixator Treatment Effectiveness in Patients With Rib Fractures
Rib Fractures · Trauma
Primary: Pain Level — 1.79; 2.85 score on a scale
Phase 2 N=100 Intercostal Liposomal Bupivacaine for the Management of Blunt Chest Wall Trauma
Blunt Chest Wall Trauma · Rib Fracture · Sternal Fracture
Primary: Opioid Requirement at 24 Hours Post-randomization — 38; 202 morphine milligram equivalents
N/A N=260 Comparison Of Chest Ultrasound Techniques To Identify Clinically Significant Pneumothorax
Pneumothorax
Primary: Pneumothorax (Positive or Negative) — 17; 21 participants
N/A N=18 Vacuum Assisted Therapy in Emergent Contaminated Abdominal Surgeries
Gastrointestinal Injury · Complicated Diverticulitis
Primary: Rate of Surgical Site Infection — 5 Participants
N/A N=84 Surgical Stabilization for Rib Fractures
Trauma Chest · Rib Fracture Multiple
Primary: Hospital Length of Stay — 9; 6 days
N/A N=46 Continuous Diffusion of Oxygen Treatment for Incision Wounds
Surgical Wound · Breast Surgery · Mammoplasty
Primary: Wound Size at 4 Weeks — 1.5; 2.75; 0.15 cm^2
N/A N=16 OxyGenesys Dissolved Oxygen Dressing; Abdominoplasty at Northwestern University
Wounds
Primary: Healing in Days. — 13.1; 12.5 days
N/A N=13 Effects of Sternal Wall Pressure in Children
Respiration, Artificial
Primary: Sternal Force Associated With Change in Intrathoracic Pressure. — 2.8 kg
Phase 4 N=121 PleuraSeal Post Market Study (Europe)
Lung Disease · Pulmonary Lobectomy
Primary: Percentage of Subjects Remaining Air Leak Free From Time of Skin Closure to Hospital Discharge. — 41.9; 30.5 Percentage of participants — p=0.257
N/A N=80 A Study of Sternal Closure After Open Heart Surgery: Rigid Versus Wire Closure
Pain
Primary: Intubation Time — 7; 9 hours
N/A N=198 Chest Tube Drainage of Transudative Pleural Effusions Hastens Liberation From Mechanical Ventilation
Liberation From Mechanical Ventilation
Primary: Total Days of Mechanical Ventilatory Support — 6.51; 4.02 days
Phase 2 N=94 A Randomized Multicenter Clinical Study On the High Vacuum Body Cavity Drainage System Following Open Heart Surgery
Coronary Artery Disease · Heart Valve Disease
Primary: Amount of Postoperative Bleeding — 868.9; 1467.6 mL
N/A N=57 Effectiveness of BoneSeal® on Bone Hemostats in Patients Undergoing Cardiothoracic Surgery
Coronary Artery Bypass Grafting
Primary: Ease of Use — 4; 1 units on a scale
N/A N=5 Biological Response of Trauma Patients to Standard Trauma Resuscitation Therapy
Hemorrhagic Shock
Primary: Biological Response as Characterized by Selected Cytokines, Specifically Tumor Necrosis Factor Alpha (TNFα), Interleukin One (IL-1β), and Interleukin Six (IL-6).
Phase 4 N=14 ABRA Abdominal Closure System in Open Abdomen Management
Open Abdomen
Primary: Primary Closure Rate — 75; 67 % of participants
N/A N=490 Active Clearance of Chest Tubes After Cardiac Surgery: A Prospective Randomized Controlled Study
Atrial Fibrillation · Pericardial Effusion · Pleural Effusion
Primary: Number of Participants With Postoperative Atrial Fibrillation — 39; 33 Participants
N/A N=111 Fluid Lavage of Open Wounds (FLOW): Pilot Trial
Infection · Wound Healing Problem · Nonunion
Primary: The Number of Participants With Re-operations (All Subsequent Operative Procedures to Treat an Infection, a Wound Healing Problem, or a Nonunion). — 7; 6; 3; 10…
N/A N=52 Chest Wall Oscillation for Asthma and COPD Exacerbations Trial (COAT)
Asthma · Chronic Obstructive Pulmonary Disease (COPD) · Undifferentiated Asthma/COPD
Primary: Patient Adherence to High Frequency Chest Wall Oscillation — 93; 91 Percent of 60 minutes prescribed
N/A N=50 Pulmonary Artery Repair With Covered Stents
Pulmonary Stenosis · Pulmonary Regurgitation · Tetralogy of Fallot
Primary: Successful Repair of Conduit Disruption — 48 participants
N/A N=10 Clinical Study of the U-Plate Fracture Repair System to Treat Rib Fractures
Rib Fracture · Flail Chest
Primary: Adverse Post-op Events Related to the Repair and Plating System — 1; 3 Participants — p=0.190
N/A N=33 EO2 Oxygen Delivery To Study Success Rate of Surgically Closed Wounds
Surgical Wound · Diabetes · Amputation Wound
Primary: Number of Participants With Unfavorable Wound Healing Outcomes at 4 Weeks — 8; 7 Participants
N/A N=283 Open Abdomen Study Comparing ABThera™ Open Abdomen Negative Pressure Therapy System and Barker's Vacuum Packing Technique
Open Abdomen
Primary: Number of Participants With Primary Fascial Closure — 139; 69 Participants — p=0.06
N/A N=88 Surgical Site Infection With 0.05% Chlorhexidine (CHG) Compared to Triple Antibiotic Irrigation
Breast Cancer
Primary: Number of Participants With Surgical Site Infection — 7; 4 participants
N/A N=4,231 Circulation Improving Resuscitation Care (CIRC)
Cardiac Arrest · Cardiopulmonary Resuscitation
Primary: Hospital Discharge — 196; 233 participants
N/A N=249 Vacuum Assisted Closure as a Treatment for Soft Tissue Injuries
Fracture of Calcaneus, Pilon or Tibial Plateau
Primary: Healing of Orthopaedic Trauma Extremity Wound Fractures (Calcaneus, Pilon and Tibial Plateau) — 99; 127 Fractures