30 closest matches · ranked by relevance
Hemorrhagic Shock
Primary: Biological Response as Characterized by Selected Cytokines, Specifically Tumor Necrosis Factor Alpha (TNFα), Interleukin One (IL-1β), and Interleukin Six (IL-6).
Trauma-related Wound · Surgical Wound, Recent
Primary: Wound Closure — 22 Participants
Orthopaedic Traumatic Open Fractures
Primary: Healing of Orthopaedic Trauma Open Fractures — 3.2; 4.0 use days
Fracture of Calcaneus, Pilon or Tibial Plateau
Primary: Healing of Orthopaedic Trauma Extremity Wound Fractures (Calcaneus, Pilon and Tibial Plateau) — 99; 127 Fractures
Burns
Primary: Decrease Hypermetabolism as Measured by Stable Isotope Infusion Study
Hemorrhagic Shock · Traumatic Brain Injury
Primary: 4 Hour Mortality — 50; 32 Participants
Posttraumatic Stress Disorder · Depression · Suicide
Primary: Change in Post Traumatic Stress Disorder (PTSD) Symptoms Over the Course of the Six Months After Injury — 47.0; 47.0; 43.9; 43.6 units on a scale — p=0.05
Open Abdomen · Abdominal Adhesions · Trauma
Primary: Adhesion Characteristics — 1.06; 1.08; 1.13; 1.08 Scores on a scale
Open Chest Wounds
Primary: Duration of Negative Pressure Wound Therapy (NWPT) — 8 Days
High Risk Pregnancy · Cesarean Wound Disruption With Postnatal Complication
Primary: Wound Complication — 13; 14 Participants
Musculoskeletal Injury Trauma
Primary: Change From Baseline, at Weeks 2, 6 and 12 on the Patient Reported Outcome Measurement Information System (PROMIS) - Physical Function Between the Groups. — 18.65; 17.6…
Wound Healing Disorder · Impaired Wound Healing · Abdominal Wound Healing Disorder
Primary: Time to Complete Wound Closure — 36.1; 39.1 Days
Skin Infections, Bacterial
Primary: Number of Participants With Clinical Success and Failure at Follow-up (7-9 Days Post Therapy) for the Primary Efficacy Population — 184; 75; 62; 38 participants — p=0.098
Open Wound Abdominal Wall · Wound Non Healing
Primary: Closure Rate of Non-healing Wounds — 45.79; 89.98 percentage of healing
Wounds
Primary: Healing in Days. — 13.1; 12.5 days
Full Thickness Skin Defects · Ulcer
Primary: Percentage Change in Wound Area — 23.73; 15.21; 34.47; 22.52 percentage change
Surgical Wound
Primary: Progression of Wound Healing — 69.9; 75.6 percentage of skin graft take
Joint Disease · Arthropathy
Primary: Visual Analog Scale (VAS) for Pain — 4.53; 4.48; 4.54 score on a scale
Donor Site Complication
Primary: Number of Participants With Treatment-related AEs and SAEs (Including Infections and Bleeding) — 0; 0; 0; 0 Participants
Trauma Injury
Primary: Percent of Patients That Complete the Protocol — 61.5; 83.3; 0 percentage of completed patients
Traumatic Lacerations or Surgical Incisions
Primary: 100% Wound Apposition at 10 Days — 77.1; 80.4 percentage of participants
Posttraumatic Stress Disorder · Depression · Alcohol-Related Disorders
Primary: Change From Baseline PTSD Checklist- Civilian (PCL-C) Over the Course of the Year After Injury — -1.65; 0.08; -4.02; -1.44 score on a scale
SURGICAL SITE INFECTION
Primary: Surgical Site Infection — 6; 3 participants — p=<0.05
Open Abdomen
Primary: Primary Closure Rate — 75; 67 % of participants
Gastrointestinal Injury · Complicated Diverticulitis
Primary: Rate of Surgical Site Infection — 5 Participants
PTSD · Physical Injury
Primary: Number of Patients With 1 or More Emergency Department Visits Per Quarter — 225; 225; 90; 79 Participants
Wound
Primary: Wound Infection — 13; 12 participants
Wounds
Primary: Wound Closure at Discharge — 100 percent of participants
Surgical Wound · Diabetes · Amputation Wound
Primary: Number of Participants With Unfavorable Wound Healing Outcomes at 4 Weeks — 8; 7 Participants
Post Traumatic Concerns · Post Traumatic Stress Disorder · Depression and Suicide Ideation
Primary: Change in Post Traumatic Concerns Over the Course of the Six Months After Injury — 80; 83; 55; 59 Participants — p==0.01