65,437 trials
Opioid Use Disorders
Primary: Opioid Use — 6; 12; 7 Participants
Pain · Anxiety
Primary: Patient Pain/Anxiety — -0.5; 0.8 units on a scale — p=0.044
Hypercholesterolemia · Dyslipidemia
Primary: Reduction of LDL Cholesterol Levels — -39.45; -29.13 percent change of LDL — p=0.0013
Atherosclerosis
Primary: Analysis of Core Phase First CEC Confirmed Major Adverse Cardiovascular Events (MACE) and Its Components — 322; 320; 313; 535 Participants — p=0.0648
Insomnia Disorder
Primary: Work and Social Adjustment Scale (WSAS) — 20.1; 19.7; 14.1; 15.8 score on a scale — p=.021
Adult Hepatocellular Carcinoma · Advanced Adult Hepatocellular Carcinoma · Localized Non-Resectable Adult Liver Carcinoma
Primary: Severe Treatment-related Toxicity — 0 Participants
Metastatic Melanoma
Primary: Number of Participants With Adverse Events/Serious Adverse Events — 12; 12; 4 Participants
Cerebral Aneurysm
Primary: Major Recurrence of Lesion or Presence of Residual Aneurysm — 26; 20 Participants
Brain Cancer · Neoplasm Metastasis · Cancer of Brain and Nervous System
Primary: Stereotactic Radiosurgery (SRS) Maximum-tolerated Dose (MTD) — 0; 0; 0; 0 Dose-limited toxicity (DLT) events
Prostate Cancer
Primary: Number of Patients With Primary Lesions Detected — 14 Participants
Medication Overuse Headache · Chronic Migraine, Headache
Primary: Visual Analog Scale — 8.3; 8.4; 5.3; 5.3 units on a scale
Healthy
Primary: Buprenorphine Plasma Cmax
Gulf War Veterans Illness · Neurobehavioral Manifestations · Memory Disorders
Primary: Digit Span Forwards — 8.7; 9.22; 8.33; 9.36 units on a scale — p=<0.01
Sjogren's Syndrome
Primary: Percentage of Participants Fulfilling Protocol-Specified Response Criteria at Week 12, as Compared to Baseline — 42.9; 43.2; 35.1; 26.5 percentage of participants…
Tooth Loss
Primary: Bone Volumetric Reduction From Baseline to 20 Weeks Post-extraction — 73.26 mm3