N/A N=21 Buprenorphine Disposition and CYP3A
Healthy
Primary: Plasma Cmax of Buprenorphine
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 1 N=16 Evaluation of Infectivity and Illness of Norwalk GI.1 Virus Lot 001-09NV in the Human Challenge Model
Norovirus Infection
Primary: Frequency of Norovirus Gastroenteritis (NVG) — 5; 4 Participants
N/A N=47 Methadone in Pediatric and Adult Sickle Cell Patients
Sickle Cell Disease
Primary: To Determine the Pharmacokinetics of Methadone in Children and Adults With Sickle Cell Disease Experiencing a VOE. — 523; 0; 637; 0 (hr*ng/ml)
Phase 2 N=32 Study of Bacillus Calmette-Guerin (BCG) Combined With PANVAC Versus BCG Alone in Adults With High Grade Non-Muscle Invasive Bladder Cancer Who Failed At Least 1 Course of BCG
Bladder Cancer
Primary: Percentage of Participants Without Recurrence (Recurrence-free Survival (RFS)) With Bacillus Calmette-Guerin (BCG) + PANVAC Compared With BCG Alone at 6 and 12 Months…
Phase 2 N=35 PET-Adjusted Intensity Modulated Radiation Therapy and Combination Chemotherapy in Treating Patients With Stage II-IV Non-small Cell Lung Cancer
Metastatic Malignant Neoplasm in the Brain · Recurrent Non-Small Cell Lung Carcinoma · Stage IIA Non-Small Cell Lung Carcinoma
Primary: Metabolic Response of All Pulmonary Lesions and Thoracic Lymph Nodes — 24 Participants
N/A N=126 Ethyl Chloride Vapocoolant as Anesthesia for Arterial Punctures
Anesthesia · Pain
Primary: Pain Level on the Visual Analog Scale (NRS-11) — 2; 2 scores on scale
N/A N=119 Individualized Nutrition for Adult Recipients of Allogeneic Stem Cell Transplants - Effect on Quality of Life
Effect of Individualized Nutrition on Quality of Life
Primary: Global Quality of Life Score — 58.8; 55.4 units on a scale
N/A N=13 Mixed Reality Gaming for Chronic Low Back Pain
Recurrent Low Back Pain
Primary: Walking Distance — 1,134.24 meters
N/A N=2,600 Chinese CLIF-C Acute-on-Chronic Liver Disease and Liver Failure Study
Liver Failure, Acute on Chronic
Primary: 28-day Mortality,28-day Liver-transplantation Free Mortality& 28-day Liver Transplantation Rate — 74; 124; 74 Participants
N/A N=31 Investigation Into the Effects of Blood Glucose Levels Upon Eating Behavior in Lean and Obese Non-diabetic and Diabetic Subjects
Diabetes
Primary: Rate of Changing Glucose Level — 0.52; 0.44 mg/dl/min
Phase 3 N=615 Study of Baricitinib (LY3009104) in Patients With Moderate to Severe Atopic Dermatitis
Atopic Dermatitis
Primary: Percentage of Participants Achieving Investigator's Global Assessment (IGA) of 0 or 1 With a ≥ 2 Point Improvement (Placebo, 2mg and 4mg Baricitinib) — 4.5; 10.6; 13.8…
Phase 2 N=13 Efavirenz and Ritonavir on Human Brain P-Glycoprotein
Drug Effects
Primary: Cerebral [11C]dLop Distribution Volume
Phase 2 N=146 Peanut Oral Immunotherapy in Children
Peanut Hypersensitivity
Primary: Percentage of Participants Desensitized to Peanut Protein After 134 Weeks of Oral Immunotherapy (OIT) — 71; 2 Percentage of Participants — p=<0.0001
Phase 2 N=12 A Study to Assess the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of GSK3389404 in Chronic Hepatitis B (CHB) Subjects
Hepatitis B
Primary: Part 1: Change From Baseline in Systolic Blood Pressure (SBP) and Diastolic Blood Pressure (DBP) at Indicated Time Points — -3.67; 3.00; 0.50; -5.33 Millimeters of…
Phase 2 N=46 T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Grafts
Acute Lymphoblastic Leukemia · Non Hodgkins Lymphoma · Myelodysplastic Syndrome
Primary: Engraftment Rate After Transplant — 100; 100 percentage of participants