N/A N=50 The Effect of Prolonged Inspiratory Time on Pulmonary Mechanics in Obese Patients
Hypoxia
Primary: PaO2(Partial Pressure of Oxygen in Arterial Blood) — 178.71; 198.04; 185.25; 202.54 mmHg
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 1 N=44 Study of the Safety, Tolerability, Pharmacokinetics and Efficacy of Pembrolizumab (MK-3475) in Chinese Participants With Non-Small-Cell Lung Cancer (MK-3475-032/KEYNOTE-032)
Non-Small-Cell Lung Cancer
Primary: Number of Participants Who Experienced an Adverse Event (AE) — 14; 13; 14 Participants
Phase 3 N=109 Fluciclovine (18F) PET/CT in biochemicAL reCurrence Of Prostate caNcer
Cancer of the Prostate
Primary: Impact on Patient Treatment /Management — 66; 38; 53; 5 Participants
Phase 3 N=661 A Study Comparing Upadacitinib (ABT-494) to Placebo in Adults With Rheumatoid Arthritis on a Stable Dose of Conventional Synthetic Disease-Modifying Antirheumatic Drugs (csDMARDs) Who Have an Inadequate Response to csDMARDs Alone
Rheumatoid Arthritis
Primary: Percentage of Participants With an American College of Rheumatology 20% (ACR20) Response at Week 12 — 35.7; 63.8; 66.2 percentage of participants — p=<0.001
Phase 3 N=152 Efficacy and Safety Assessment of T4020 Versus Vehicule in Patients With Chronic Neurotrophic Keratitis or Corneal Ulcer
Keratitis · Corneal Ulcer
Primary: Number of Participants With a Reduction in Neurotrophic the Keratitis/Ulcer Area on Day28 — 37; 44 Participants
Phase 3 N=499 A Study to Compare Upadacitinib (ABT-494) to Placebo in Adults With Rheumatoid Arthritis on Stable Dose of Conventional Synthetic Disease-Modifying Antirheumatic Drugs (csDMARDs) With an Inadequate Response or Intolerance to Biologic DMARDs
Rheumatoid Arthritis
Primary: Percentage of Participants With an American College of Rheumatology 20% (ACR20) Response at Week 12 — 28.4; 64.6; 56.4 percentage of participants — p=<0.001
N/A N=240 Evaluation of an Online Intervention to Help LGBTQ Youth Cope With Bullying
Bullying of Child
Primary: Number of Participants With Changes in Help Seeking Scores — 28; 28; 44; 55 Participants
Phase 3 N=101 Preoperative Acetaminophen and Carbohydrate Loading
Non-melanoma Skin Cancer
Primary: Maximum Pain Score — 2.8; 1.2 units on a pain scale
N/A N=135 Performance and Safety Assessment of T4020 in Managing Corneal Epithelial Defect Following Epi-off Accelerated Crosslinking
Keratoconus
Primary: Number of Participants With Complete Healing of Corneal Epithelial Defect at Day 3 — 20; 25 Participants
N/A N=2 Pilot Study of Pre-Ischemic Conditioning for Intracranial Atherosclerosis
Intracranial Atherosclerosis
Primary: Percent Change in Cerebral Blood Flow (CBF) — 0; 25 percentage increase in CBF
N/A N=184 Brain Nicotine Receptor Density in Veteran Smokers
Positron Emission Tomography
Primary: PET Scan, Rating Scales — 7.1; 8.6; 7.9; 8.0 Vt/fp or mL/cm3
N/A N=119 Development and Pilot Testing of a Multimodal Web-based Program to Address Heavy Drinking During Smoking Cessation
Smoking Cessation · Alcohol Drinking
Primary: Number of Participants Who Reported 7-day Point-prevalence Smoking Abstinence at 1 Month — 10; 10 Participants — p=.90
Phase 4 N=80 Ketamine Effect After Laparoscopic Gastric Reduction: A Randomized, Double-Blinded, Placebo Controlled Study
Pain · Obesity · Hypoxia
Primary: Quality of Recovery 40 — 170; 179 score on a scale
Phase 2 N=239 IX-01 Effect on Intravaginal Ejaculatory Latency Time (IELT), Patient Reported Outcomes and Safety in Men With Premature Ejaculation (PE)
Premature Ejaculation
Primary: Change From Baseline in Geometric Mean (GM) Intravaginal Ejaculatory Latency Time (IELT) Over the Treatment Assessment Period — 42.6; 39.7; 44.5; 29.2 Seconds
N/A N=20 Clinical Comparison of Electrocardiograms Collected Using an Ambulatory Holter
Electrocardiography
Primary: Arrythmia — 4.6; 7.95 Quality rating