65,437 trials
Opioid-Induced Constipation
Primary: Average Percentage of Dosing Days That Resulted in Rescue-Free Bowel Movements (RFBMs) Within 4 Hours of Dosing During Weeks 1 to 4 — 21.05; 24.64; 27.40; 18.18…
Breast Cancer
Primary: Percent Correct on the Knowledge Measure (Objective Knowledge Score) — 84.6; 59.7 percentage of answers correct
Drug-specific Antibodies · Diabetes Mellitus
Primary: Percentage of Participants With Treatment-emergent Anti-Drug Antibody (ADA) — 0; 2.0 percentage of participants
Asthma
Primary: Change in Overall Asthma Symptoms From Baseline — -0.60; -0.15; -0.88; -0.48 units on a scale
Pain, Postoperative
Primary: Quantity of Opioids Used in the First 48 Hours Postoperatively — 10.71; 11.14 mg of Dilaudid
Soccer · Exercise · Athletic Performance
Primary: Percentage Change From Baseline in 10m Sprint Times After an 8 Week Intervention — 4.13; -1.08 Percentage of change
Back Pain
Primary: 6 Minute Walk Test — 245.2; 234.7; 233.9 meters
Nicotine Dependence
Primary: Point Prevalence Tobacco Abstinence — 25; 11 Participants
Hypotension · Critical Illness
Primary: Time Until Discontinuation of IV Vasopressors — 23.5; 22.5 hours
Hypertension
Primary: Renal Oxygenation Changes After Chronic Treatment With Aliskiren or Hydrochlorothiazide — 20.5; 19.5; 19.5; 20.5 1/sec
Deep Vein Thrombosis · Venous Thrombosis
Primary: Comfort and Patient Acceptance — 8.89 score on a scale
Chronic Myelomonocytic Leukemia · Myelodysplastic Syndrome With Isolated Del(5q) · Myelodysplastic/Myeloproliferative Neoplasm
Primary: Complete Response Rate (CR or CRi) Per the National Comprehensive Cancer Network (NCCN) Guidelines or According to Specific Criteria From Expert Panels — 0 percentage of…
Adult Giant Cell Glioblastoma · Adult Glioblastoma · Adult Gliosarcoma
Primary: Change From Baseline in Maximum Standard Uptake Values (SUVmax) — -0.98; 0.09; 0.10; -1.90 ratio
Hereditary Hemorrhagic Telangiectasia (HHT)
Primary: Measurement of Epistaxis in Patients With HHT as Measured by the HHT Foundation Epistaxis Severity Score, Hematocrit, Hemoglobin and Serum Ferritin Levels.
Carcinoma, Non-Small-Cell Lung · Non-small Cell Lung Cancer · NSCLC
Primary: Progression Free Survival — 7.4; 8.1 Months — p=0.165