12,372 trials
Surgery · Analgesia
Primary: Analgesia Assessed by the Area Under the Curve of Visual Analog Scale Pain Intensity Scores — 87.1; 92.8 VAS score x Hours
Primary Immunodeficiency Diseases (PID)
Primary: Percentage of Participants With Treatment-Emergent Adverse Events (TEAEs) — 100 percentage of participants
Respiratory Syncytial Virus Infections
Primary: RSV-A Neutralizing Titers Expressed as Adjusted Geometric Mean Titers (GMTs) at 1 Month Post RSVPreF3 OA Vaccination — 5676.7; 6329.5 Titer
Metastatic Pancreatic Ductal Adenocarcinoma
Primary: Safety run-in Part: Percentage of Participants With Dose Limiting Toxicities (DLTs) During the First Cycle (4 Weeks) of Treatment. — 0 Participants
Social Anxiety Disorder
Primary: Change From Baseline to the Average Subjective Units of Distress Scale (SUDS) Score of the 5-minute Performance Phase of a Public Speaking Challenge — 27.2; 26.0 score…
Relapsing-Remitting Multiple Sclerosis
Primary: Part 1: Proportion of Participants Free of New or Newly Enlarging T2 Hyperintense Lesions on Brain Magnetic Resonance Imaging (MRI) Scans — 0.161; 0.049 proportion of…
Asthma
Primary: Annualized Rate of Clinically Significant Exacerbations Over 52 Weeks — 0.57; 0.49 Exacerbation per participant per year — p=0.079
Overweight · Obesity
Primary: Change in Body Weight (%) — -12.2; -2.2 Percentage change in body weight — p=<0.0001
Meningioma
Primary: The Percentage of Participants Who Had at Least 1 Indeterminate Tissue or Unexpected Fluorescent End of Surgery (EOS) Tissue Where Gleolan-induced PpIX Fluorescence…
Schizophrenia · Schizoaffective Disorder
Primary: Positive & Negative Symptom Scale Total (PANSSt) — 56.77; 54.24; 52.23; 49.29 score on a scale — p=0.004
Allergic Conjunctivitis
Primary: Subject-Reported Ocular Itching Score Assessed in the Allergy Chamber — 1.48; 1.84 units on a scale
Pleural Mesothelioma Malignant Advanced
Primary: Overall Survival (OS) — 20.5; 18.1 months — p=0.14
Wound of Skin · Wound Heal · Wound Open
Primary: Number of Participants With Re-epithelialization at 30 Days Post op — 9; 12 participants — p=0.580
HIV · HIV Infections
Primary: Number of Participants With Plasma HIV-1 Ribonucleic Acid (RNA) Greater Than or Equal to (>=)50 Copies/Millilitre (c/mL) at Week 48 — 2 Participants
Functional Constipation (FC) · Chronic Idiopathic Constipation (CIC)
Primary: Change From Baseline in 12-week Spontaneous Bowel Movement (SBM) Frequency Rate (SBMs/Week) Observed by the Primary Caregiver During the Double-blind Study Intervention…