Phase 4 N=30 Effect of Electronic Cigarette Use on Cough Reflex Sensitivity
Cough
Primary: Change in Cough Reflex Sensitivity (Log C5) — -0.29; 0.24 log C5
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=162 The Clinical Investigation of a Zinc Based Toothpaste in Reducing Plaque and Gingivitis
Dental Plaque and Gingivitis
Primary: Gingivitis Scores — 1.48; 1.57; 1.49 units on a scale — p=0.091
N/A N=102 Saphenous Vein Cannulation in Infants and Small Children
Saphenous Vein Cannulation
Primary: Percentage of Participants With First Attempt Success of Saphenous Vein Cannulation — 51.0; 90.2 percent of participants
Phase 3 N=298 Treatment Options for Protease Inhibitor-exposed Children
HIV/AIDS · HIV Infections
Primary: Viral Rebound — 0.284; 0.176 probability of viral rebound — p=<0.001
Phase 4 N=10,000 Post-licensure Safety Study of IMOJEV® in Thailand
Japanese Encephalitis
Primary: Number of Participants Experiencing a Grade 3 Immediate Systemic Adverse Events and Serious Adverse Events Following Any Vaccination With IMOJEV® — 0; 0; 204; 59…
Phase 3 N=1,561 Selenium in Preventing Tumor Growth in Patients With Previously Resected Stage I Non-small Cell Lung Cancer
Lung Cancer
Primary: Incidence Rate of Second Primary Lung Tumor — 1.30; 1.62 cases/100 person years — p=0.294
N/A N=51 The Esteem® Hearing Implant Post Approval Study
Hearing Loss
Primary: Change From Baseline (Pre-implant Aided Condition) at Year 5 in Speech Reception Threshold (SRT) — 4.8 dB
Phase 2 N=72 A Study to Evaluate the Safety of AERAS-402 in Adults Recently Treated for Pulmonary TB
Tuberculosis
Primary: Number of Participants With Solicited and Unsolicited AEs — 11; 10; 20; 30 participants
N/A N=40 Clinical Performance of Habitual Wearers of Bioclear 1-day Lenses When Refitted With Biomedics 1-day Extra for 1 Week
Myopia · Hyperopia
Primary: Lens Fit, Centration - Filcon IV 1 and Ocufilcon D — 58; 70; 98; 98 percentage of eyes
Phase 2 N=73 Mismatched Family Member Donor Transplantation for Children and Young Adults With High Risk Hematological Malignancies
Leukemia, Acute Lymphocytic (ALL) · Leukemia, Myeloid, Acute(AML) · Leukemia, Myeloid, Chronic(CML)
Primary: Event-free Survival (EFS) — 54.8 Percentage of participants
N/A N=122 Detection Of Neoplastic Tissue in Barrett's Esophagus With In vivO Probe-based Confocal Endomicroscopy
Barrett Syndrome · Barrett's Syndrome · Barrett's Esophagus
Primary: Comparative Histopathology-confirmed Measures of Per Lesion Sensitivity and Per Lesion Specificity, by Using pCLE Associated With WLE, or WLE Alone, for the Detection of…
Phase 2 N=67 BYM338 in Chronic Obstructive Pulmonary Disease (COPD) Patients With Cachexia
Chronic Obstructive Pulmonary Disease (COPD) With Cachexia
Primary: Percentage Change From Baseline of Thigh Muscle Volume (TMV) by MRI Scan at Week 4, 8, 16, and 24 — 5.87; 0.02; 7.01; -0.65 Percentage Change of TMV — p=<0.001
Phase 4 N=2,681 PROMUS Element Plus US Post-Approval Study
Coronary Artery Disease
Primary: Cardiac Death or Myocardial Infarction Rate in PLATINUM-like Patients — 1.78 percentage of patients — p=<.0001
Phase 4 N=66 A Study of Bone Turnover Markers in Post-Menopausal Women With Osteoporosis Treated With Monthly Boniva (Ibandronate)
Post Menopausal Osteoporosis
Primary: Relative Percent Change in Serum C-terminal Telopeptide of Type 1 Collagen Concentration (sCTX) From Baseline to Day 3 — -70.16; -5.96 Percent change — p=< 0.0001
N/A N=12 A Bioavailability Study of Nicotine Delivered by an Electronic Vapour Product
Healthy Volunteers
Primary: Nicotine Plasma Concentration — 3.6; 2.5; 2.5; 21.2 ng/ml