Phase 4 N=665 Combining Medications to Enhance Depression Outcomes
Major Depressive Disorder
Primary: Quick Inventory of Depressive Symptoms — 46.6; 41.8; 46.0 percentage of participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=30 Ziprasidone Switching in Response to Adherence and Psychotropic-Related Weight Gain Concerns Among Patients With Bipolar Disorder (Zip Ad)
Medication Adherence · Bipolar Disorder
Primary: Treatment Non-adherence Percentage as Measured by the Tablet Routines Questionnaire (TRQ) — 16.11; 13.88 Percentage of doses
Phase 4 N=49 The Muscle Relaxation-study
Cholecystectomy, Laparoscopic
Primary: The Percentage of Patients With Optimal Surgical Space Conditions ( 1 at a 4-step Scale) Assessed at the Time During Surgery, When View Was Less — 28; 4 percentage of…
Phase 4 N=74 Tenaculum Pain Control Study
Cervical Pain · Pelvic Pain
Primary: Tenaculum Pain — 12.3; 36.6 mm
Phase 4 N=56 A Comparison of Three Different Formulations of Prednisolone Acetate 1%
Glaucoma · Cataract
Primary: Percent Change in Flare at Resolution — 64.8; 68.3; 65.7 Percent change in flare
Phase 4 N=49 Pilot Study Evaluating Alterations in Thrombogenicity and Platelet Reactivity Following Lower Extremity Arthroplasty
Primary Total Hip and Knee Arthroplasty
Primary: Blood Loss — 6; 1 participants
Phase 4 N=30 Single Site, Masked, Randomized, Controlled Study to Assess Efficacy of Osurdex as Adjunct to Avastin Compared With Avastin Alone in the Treatment of Patients With Macular Edema Due to Central or Branch Retinal Vein Occlusion
Retinal Vein Occlusions
Primary: Change From Baseline Visual Acuity at 6 Months — 2.3; 0.1 ETDRS score
Phase 4 N=19 Natalizumab De-escalation With Interferon Beta-1b
Relapsing-remitting Multiple Sclerosis
Primary: Number of Days Until First On-study Relapse — NA; 103 days — p=0.125
Phase 4 N=84 A Comparison of Postoperative Tramadol Versus Acetaminophen With Codeine in Children Undergoing Tonsillectomy
Tonsillitis · Pain
Primary: Efficacy of Two Different Liquid Pain Medications: Tramadol vs. Codeine/Acetaminophen During the Post-tonsillectomy Recovery Period. — 1.5; 1 days
Phase 4 N=60 Safety and Immunogenicity Among Healthy Children Receiving Fluzone® Influenza Virus Vaccine (2012-2013 Formulation)
Influenza
Primary: Number of Participants Reporting Solicited Injection Site or Systemic Reactions Following Vaccination With Fluzone® Influenza Virus Vaccine (2012-2013 Formulation) — 8…
Phase 4 N=38 Coenzyme Q10 Supplementation in Children With Idiopathic Dilated Cardiomyopathy
Dilated Cardiomyopathy
Primary: Improvement in Left Ventricular Ejection Fraction — 42.1; 37.6 Percentage — p=0.267
Phase 4 N=92 Boston Scientific OffRoad™ Re-entry Catheter System for Subintimal Recanalization of Chronic Total Occlusions in Femoropopliteal Arteries
Chronic Total Occlusion
Primary: Composite Rate of Major Adverse Events — 3.3 percentage of participants
Phase 4 N=255 Comparing Patient Comfort and Safety Between Iodixanol and Iopamidol in Patients Undergoing Peripheral Arteriography
Drug Safety
Primary: Subjects Experiencing Discomfort When Undergoing Peripheral Arteriography — 53; 92; 48; 82 participants
Phase 4 N=24 How Vitamin D Analogues Affect Endothelial Cells in Patients on Dialysis
Hyperparathyroidism, Secondary · Kidney Failure, Chronic
Primary: Change in Endothelial Cell Function — .23 percent change in FMD
Phase 4 N=15 A Study to Evaluate the Mode of Administration and Safety of EUR-1008 (APT-1008) in Infants 1 to 12 Months of Age
Cystic Fibrosis · Exocrine Pancreatic Insufficiency
Primary: Treatment Difference for Acceptability of Treatment — 1.5; 3.5; 2.5; 1.0 units on a scale