12,372 trials
Pain Control
Primary: Effect of Transversus Abdominis Plane (TAP) Block Using Either 0.5% or 0.25% Bupivacaine on Analgesia for Cesarean Section Patients When Compared to Placebo. — 9.45…
Acute Renal Failure · Kidney Disease · Coronary Artery Disease
Primary: Number of Participants With Serious, Adverse, Patient-Centered Events, Including Death, Need for Acute Dialysis, or Persistent Decline in Kidney Function, Comparing…
Human Immunodeficiency Virus Type 1
Primary: Percentage of Participants With Virologic Rebound (HIV-1 RNA >=50 Copies/mL) Cumulative Through Week 48 — 2.5; 2.1 Percentage of participants — p=<0.001
Post Operative Pain · Pain
Primary: Postoperative Pain as Measured on a 11-point Numerical Rating Scale — 3.5; 4.9 units on a scale — p=0.009
Chronic Obstructive Pulmonary Disease
Primary: Change From Baseline in 1-hour Morning Post-dose Dose Forced Expiratory Volume in 1 Second (FEV1) of AB/FF 400/12 μg Compared to AB 400 μg at Week 24 — 0.253; 0.169…
Colonoscopy
Primary: Success Rates of the Procedure — 272; 1; 26 Participants — p=<0.0001
Migraine
Primary: Change From Baseline in the Monthly Average Number of Migraine Days During the 12-Week Period After the First Dose of Study Drug — -2.7; -4.0; -4.2 days — p=<0.0001
Postmenopausal Osteoporosis
Primary: Percentage of Participants With New Vertebral Fracture Through Month 12 — 1.8; 0.5 percentage of participants — p=< 0.001
Anemia in Chronic Kidney Disease Patients Not on Dialysis
Primary: Percentage of Participants in Receipt of 1 or More RBC Transfusions — 24.40; 24.14 Percentage of Participants
Postmenopausal Osteoporosis
Primary: Percent Change From Baseline in Bone Mineral Density (BMD) at the Lumbar Spine — 0.8; 9.6; 9.2 percent change
Postmenopausal Osteoporosis
Primary: Percent Change From Baseline Through Month 12 in Total Hip Bone Mineral Density (BMD) — -0.6; 2.6 percent change — p=< 0.0001
Gastric Cancer
Primary: Overall Survival — 82; 62 participants — p=0.0262
Autism Spectrum Disorders
Primary: Mean 10-Week Change in Pediatric Anxiety Rating Scale 5-Item Total Score, Double-blind Phase — -4.9; -3.2 score on a scale
Alloimmune Thrombocytopenia · Fetal Alloimmune Thrombocytopenia
Primary: Number of Newborns With a Birth Platelet Count > 50,000/uL — 48; 47 number of newborns with >50,000 pets
Tuberous Sclerosis Complex-associated Refractory Seizures
Primary: Core Phase: European Medicine Agency (EMA): Seizure Frequency Response Rate — 28.2; 40.0; 15.1 Percentage of responders — p=0.008