65,437 trials
Participants With or Without Stable Co-morbidities Associated With Progression to Severe COVID-19
Primary: Double Blind Phase: Number of Participants With First Occurrence of Molecularly Confirmed Moderate to Severe/Critical COVID-19 in Seronegative Participants With Onset at…
Tobacco Use
Primary: Number of Cigarettes Purchased — 154.7; 119.2 average number of cigarettes
Tricuspid Regurgitation
Primary: Composite Major Adverse Event (MAE) Rate — 6 Participants
Heart Failure · Heart Failure With Reduced Ejection Fraction
Primary: Number of Participants Prescribed Mineralocorticoid Receptor Antagonists (MRA) During Study — 224; 127; 75 Participants
Obesity
Primary: Cohorts 1 and 2: Percent Change From Baseline in Body Weight at End of Treatment at Week 26 — 0.17; -5.43; -4.83; -8.94 Percent change — p=<.0001
Metastatic Carcinoma in the Liver · Resectable Mass · Stage IV Colorectal Cancer AJCC v7
Primary: Post-operative Toxicity — 8 Participants
Non-infectious Uveitis
Primary: Evaluation of Safety and Tolerability by Determining Treatment Emergent Adverse Events — 12 Participants
Smoking
Primary: Self-reported 7-day Point Prevalence Abstinence From Smoking That Was Sustained at 60 Days After the Quit Date — 26; 14 Participants
Atopic Dermatitis Eczema
Primary: Achievement of Validated Investigator Global Assessment for Atopic Dermatitis (vIGA-AD) Success at Week 4 — 32.0; 15.2 percentage of participants — p=<0.0001
Human Papillomavirus Infection
Primary: Acceptability of Providing HPV Vaccination to Children and of the Proposed Communication Strategy to Support HPV Vaccination — 4.1 units on a scale
Bone Marrow Transplant · Information Disclosure · Hematopoietic Stem Cell Transplantation
Primary: Changes From Baseline Profile of Mood States (POMS) Short Version (Emotional Well-being or /Reduction of Emotional Distress) at 4 Weeks — 3.3; 3.4; 2.4; 2.8 score on a…
Non-small Cell Lung Cancer Stage IV
Primary: Efficacy of Atezolizumab + CBDCA + Pemetrexed by Evaluating PFS Rate — 62.2 percentage of participants
Squamous Cell Carcinoma · Skin Cancer · Keratoacanthoma
Primary: Overall Response Rate — 11; 1; 10 Participants — p=0.0005
SARS-CoV-2 Infection
Primary: Change From Baseline in Logarithm Base 10 (Log10) Transformed Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Ribo Nucleic Acid (RNA) Level on Day 5…
Breast Neoplasms
Primary: Evaluation of the Occurrence of Nail Toxicity of Grade 2 of Common Toxicity Criteria for Adverse Effects V4.0 Evaluated at 8 Weeks Post Infusion of Docetaxel. — 26; 49…