65,437 trials
Solid Tumor Malignancy · Hematologic Malignancy · Leukemia
Primary: Number of Participants With Grades 1-5 Solicited (Expected) and/or Unsolicited (Unexpected) Adverse Events (AE's): Initial Phase — 0; 0; 1; 0 Participants
Depression · Major Depressive Disorder
Primary: Depressive Symptoms as Measured by the Inventory of Depressive Symptomatology - Clinician Rated (IDS-CR) — 17.93; 29.63 units on a scale
Alcohol Use Disorder Cognitive Decline
Primary: Days of Heavy Alcohol Use Assessed by Weekly Time Line Follow-back and Breathalyzer — 5.49; 3.0 Days — p=<.05
Idiopathic Scoliosis
Primary: Postoperative Pain (Total Opioid Use) — 0.041; 0.048; 0.054; 0.038 mg/kg/hr
Brain Concussion
Primary: Brief Symptom Inventory-18 (BSI-18) Global Severity Index T-Score — 64.21; 65.26; 66.8; 61.35 units on a scale — p=.04
Myopia
Primary: Overall Vision Satisfaction — 87.7; 79.7; 71.8 units on a scale
Corneal Ulcer · Infectious Keratitis · Bacterial Ulcer
Primary: Microbiological Cure on Repeat Culture — 5; 5; 17; 14 Participants
Eosinophilic Esophagitis (EoE)
Primary: Part A: Percentage of Participants Achieving Peak Esophageal Intraepithelial Eosinophil Count of Less Than or Equal to (≤) 6 Eosinophils/High Power Field (Eos/Hpf) at…
Non-invasive Urine Output Management
Primary: Performance of the PureWick MEC Against an Established Comparator — 97.8; 90.7; 91.1; 85.2 Percentage of urine captured — p=0.04
Rheumatoid Arthritis · Psoriatic Arthritis
Primary: Number of Participants With Adverse Events (AEs), Adverse Drug Reactions (ADRs), Serious Adverse Events (SAEs) and Serious Adverse Drug Reactions (SADRs) — 261; 148; 40…
Prurigo Nodularis
Primary: Percentage of Participants Achieving ≥4-point Improvement in Itch Numerical Rating Scale (NRS) Score at Week 16 — 8.1; 36.1; 44.4; 56.8 percentage of participants…
HIV-infected Participants With ESRD Undergoing Routine Hemodialysis
Primary: Percentatge of Doravirine Dialysis Extraction Ratio (ER) — 34.3 percentage of doravirine dialysis ER
Pneumococcal Immunization
Primary: Geometric Mean Titers (GMTs) of Pneumococcal Serotypes Using Serotype-Specific MOPA — 128; 127; 158; 254 Titer
Aphasia · Spatial Neglect · Stroke
Primary: Client Satisfaction Questionnaire — 32; 27 score on a scale
HIV-1
Primary: Percent Change From Baseline in Body Weight at Week 24 — 0.63; -0.24 Percent Change