Phase 4 N=71 The Use of Belladonna and Opium Suppository in the Treatment of Postoperative Stent Pain
Nephrolithiasis
Primary: Global Quality of Life Score on Postoperative Day 1 — 4.4; 5.4 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=353 Chronic Pain Risk Associated With Menstrual Period Pain
Cystitis, Interstitial · Dysmenorrhea · Migraine Disorders
Primary: Change in Participant Bladder Pain Sensitivity From Baseline. — 38.2; 37.0; 41.2; 47.9 score on a scale — p=.02
Phase 4 N=1,041 An Investigational Immuno-therapy Study for Safety of Nivolumab in Combination With Ipilimumab to Treat Advanced Cancers
Lung Cancer
Primary: Number of Participants With High Grade (Grade 3-4 and Grade 5) Drug-Related Select Adverse Events (AEs) — 19; 15; 4; 0 Participants
Phase 4 N=70 Effectiveness of Orally Dosed Emergency Contraception in Obese Women - LNG
Obesity
Primary: The Number of Participants in Two Treatment Groups (1.5mg Levonorgestrel and 3mg Levonorgestrel) With no Follicle Rupture at 5 Days Within One Menstrual (Treatment)…
Phase 4 N=79 Treatment of Insomnia in Migraineurs
Insomnia · Migraine
Primary: Total Sleep Time — 5.4; 5.5; 6.3; 6.1 hours — p=0.33
Phase 4 N=22 Prebiotic Treatment in People With Schizophrenia - Pilot Study
Schizophrenia · Schizoaffective Disorder
Primary: Change in Serum Butyrate Levels — 2.42; 2.34; 2.88; 2.40 mg/ml
Phase 4 N=6 CES1 Carriers in the PAPI Study
Heart Diseases · Coronary Disease · Coronary Artery Disease
Primary: Changes in Platelet Function in Response to Clopidogrel — 37.4; 20.4 percentage of maximum aggregation change
Phase 4 N=41 Adjunctive Mixed Salts Amphetamine for Depressed Adults With Incomplete Response to Current Antidepressant Therapy
Major Depressive Disorder
Primary: Change in Scores on the Massachusetts General Hospital Cognitive and Physical Functioning Questionnaire (MGH-CPFQ) — 27.5; 29; 22.6; 25 Scores on a scale
Phase 4 N=93 A Study to Learn if Recombinant Human Parathyroid Hormone [rhPTH(1-84)] Can Improve Symptoms and Metabolic Control in Adults With Hypoparathyroidism (BALANCE)
Hypoparathyroidism
Primary: Change From Baseline in Hypoparathyroidism Symptom Diary (HypoPT-SD) Symptom Subscale Score at Week 26 — -0.93; -1.46 score on a scale — p==0.003
Phase 4 N=37 Responses to Rabies Vaccine in Adults With or Without Antibiotics
Rabies Human
Primary: Antibody Titers — 217.39; 805.64 IU/mL
Phase 4 N=5 Shoulder Contraceptive Implant Study
Contraception
Primary: Pharmacokinetics in the Form of Serum Etonogestrel Concentrations — 511.7; 136.6 pg/mL
Phase 4 N=32 Effect of Dapagliflozin on Hepatic and Renal Glucose Metabolism Subjects
Diabetes Mellitus, Type 2
Primary: Endogenous Glucose Production Measurement — 155; 121; 104; 98 mg/dl
Phase 4 N=100 Envarsus in Delayed Graft Function (E-DGF)
Delayed Graft Function
Primary: Number of Days Needed to Recover From Delayed Graft Function (DGF) — 14.0; 15.0 days
Phase 4 N=129 Toward Zero Prescribed Opioids for Outpatient General Surgery
Opioid Misuse and Addiction · Pain
Primary: Morphine Milligram Equivalents Taken by Participants — 46; 15; 0 morphine milligram equivalents
Phase 4 N=27 Suvorexant and Sleep's Benefits to Therapeutic Exposure for Posttraumatic Stress Disorder
Posttraumatic Stress Disorder
Primary: The Clinician Administered PTSD Scale for DSM-5 (CAPS-5) Score at Week 2 — 16.6; 17.1 score on a scale