N/A N=41 Damage Control for Duodenal and Combined Duodenal-Pancreatic Injuries
Injury of Duodenum · Pancreatic Injury
Primary: Duodenal-related Complications — 13; 11; 8; 19 percentage of subjects
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=14 ABRA Abdominal Closure System in Open Abdomen Management
Open Abdomen
Primary: Primary Closure Rate — 75; 67 % of participants
Phase 3 N=56 Early Short-term Antibiotic Therapy in Penetrating Abdominal Trauma, 3 vs 7 Days
SURGICAL SITE INFECTION
Primary: Surgical Site Infection — 6; 3 participants — p=<0.05
Phase 4 N=267 BEFAST (Bubble-Enhanced FAST) for the Evaluation of Solid Organ Injury
Abdominal Trauma
Primary: Sensitivity of Detecting Solid Organ Injury Measured as the Number of True Positives — 18; 20 Participants
N/A N=5 Biological Response of Trauma Patients to Standard Trauma Resuscitation Therapy
Hemorrhagic Shock
Primary: Biological Response as Characterized by Selected Cytokines, Specifically Tumor Necrosis Factor Alpha (TNFα), Interleukin One (IL-1β), and Interleukin Six (IL-6).
N/A N=20 Endovascular Repair for the Descending Thoracic Aorta
Aorta Thoracic; Traumatic Rupture
Primary: Number of Participants With Major Adverse Events — 0 number of serious adverse events
N/A N=182 A Study to Improve the FAST Ultrasound Exam
Hemoperitoneum
Primary: Number of Subjects Screening Positive for Blood Around the Abdominal Organs (Hemoperitoneum) After Trauma, as Assessed by Focused Assessment With Sonography for Trauma…
N/A N=30 Seprafilm in Open Abdomens: a Study of Wound and Adhesion Characteristics in Trauma Damage Control Patients
Open Abdomen · Abdominal Adhesions · Trauma
Primary: Adhesion Characteristics — 1.06; 1.08; 1.13; 1.08 Scores on a scale
N/A N=7 Direct Peritoneal Resuscitation Effects in the Damage Control Patient
Traumatic Injury
Primary: Number of Participants With Morbidity — 0; 0 number of participants
N/A N=334 Independent Predictors of Mortality in Polytrauma Patients
Multiple Trauma
Primary: Death — 52 participants — p=< 0.001
N/A N=18 Vacuum Assisted Therapy in Emergent Contaminated Abdominal Surgeries
Gastrointestinal Injury · Complicated Diverticulitis
Primary: Rate of Surgical Site Infection — 5 Participants
N/A N=39 Damage Control Laparotomy
Other Injury of Other Intra-abdominal Organs, Initial Encounter
Primary: Number of Participants Who Died or Had Major Abdominal Complication (MAC) — 6; 12; 6; 8 Participants
Phase 2 N=31 Traumatic Injury Clinical Trial Evaluating Tranexamic Acid in Children: A Pilot and Feasibility Study
Brain Injuries · Wounds and Injuries · Hemorrhage
Primary: Pediatric Quality of Life Inventory (PedsQL) — 64.9; 60.2; 67.2 Quality of life units * months
N/A N=50 Pre-hospital Advanced Therapies for Control of Hemorrhage - Pelvis
Hemorrhage · Pelvic Fracture
Primary: Mortality Rate — 0; 1 Participants
N/A N=283 Open Abdomen Study Comparing ABThera™ Open Abdomen Negative Pressure Therapy System and Barker's Vacuum Packing Technique
Open Abdomen
Primary: Number of Participants With Primary Fascial Closure — 139; 69 Participants — p=0.06
N/A N=1,051 Shock, Whole Blood, and Assessment of TBI S.W.A.T. (LITES TO 2)
Hemorrhagic Shock · Traumatic Brain Injury
Primary: 4 Hour Mortality — 50; 32 Participants
N/A N=30 Evaluation of Etomidate on Adrenal Function in Trauma Patients
Adrenal Insufficiency
Primary: Cortisol Levels Pre and Post Rapid Sequence Induction and Cortisol Stimulation Test
Phase 3 N=199 Low-Titer O Positive Whole Blood Versus Component Therapy for Emergent Transfusion in Trauma Patients
Hemorrhagic Shock · Acute Blood Loss Anemia · Traumatic Brain Injury
Primary: Packed Red Blood Cells Equivalents Units Transfused (1 Whole Blood Unit Treated as 1 Packed Red Blood Cell Unit and 1 Fresh Frozen Plasma Unit) — 3.8; 5.7 units
N/A N=50 Effect of Remote Ischemic Conditioning on Trauma Patients With Hemorrhagic Shock
Hemorrhagic Shock
Primary: Neutrophil Oxidative Burst Activity — 302; 302; 298; 268 Median Fluorescence Intensity — p=0.56
N/A N=95 Heart Rate Variability in Trauma Patients
Trauma
Primary: Base Deficit </= -6 — 12 participants
Phase 4 N=100 ORthopaedic Trauma Anemia With Conservative Versus Liberal Transfusion
Anemia
Primary: Postoperative Wound Infection (Superficial or Deep) or Other Perioperative Infection — 12; 3 Participants — p=.0122
N/A N=48 Embolization in Splenic Trauma
Trauma to the Spleen
Primary: Number of Participants Who Were Enrolled Within 18 Months of Study Initiation — 23; 23 Participants
N/A N=30 Intra-Abdominal Hypertension in Neonatal Intensive Care Patients
Intra-Abdominal Hypertension
Primary: Intra-abdominal Pressure(IAP) Measurements in NICU Patients. — 1219 IAP measurements
N/A N=119 Optimal Fluid Resuscitation for Trauma Patients
Trauma
Primary: Mortality — 0 participants
Phase 4 N=94 Study Of Tranexamic Acid For The Reduction Of Blood Loss In Patients Undergoing Major Abdominal Surgery
Biliary Tract Surgical Procedures · Pancreaticoduodenectomy · Esophagectomy
Primary: Post-operative Blood Loss — 394.3; 494.3 milliliter (mL) — p=0.460
Phase 3 N=87 The Use of Fondaparinux in Preventing Thromboembolism in High Risk Trauma Patients
Venous Thromboembolism
Primary: Presence of Deep Vein Thrombosis (DVT) or Pulmonary Embolus (PE) — 2; 2; 1; NA participants
N/A N=260 Comparison Of Chest Ultrasound Techniques To Identify Clinically Significant Pneumothorax
Pneumothorax
Primary: Pneumothorax (Positive or Negative) — 17; 21 participants
N/A N=989 Improving Initial Management of the Injured at Ghanaian District and Regional Hospitals With a Trauma Intake Form
Behavior Problem
Primary: Appropriate Use of Key Performance Indicators in Initial Assessment and Management of the Injured at Non-tertiary Hospitals in Ghana — 1807; 1894; 1194; 1787…
N/A N=20 ICG Fluorescence Imaging in Trauma Patients
Trauma Injury
Primary: Percent of Patients That Complete the Protocol — 61.5; 83.3; 0 percentage of completed patients
N/A N=34 Blood Flow Restriction Training Combined With Abdominal draw-in Maneuver on Transverse Abdominis Strengthening
Blood Flow Restriction · draw-in Maneuver · Transverse Abdominis
Primary: Muscle Thickness Change of Transverse Abdominis — 0.93; 0.77; 1.98; 0.99 mm