Clinical Trial Search

Primary: Pain Intensity — 2.8; 3.0; 2.8; 3.0 score on a scale — p=0.16

Primary: Change in Functional Impairment as Measured by the Roland Morris Disability Questionnaire — 11.1; 11.9 units on a scale

Primary: Number of Patients Who Reported Transition From Acute to Chronic Low Back Pain (cLBP) — 312; 318 Participants

Primary: Change in Functional Disability as Measured by the Roland Morris Disability Questionnaire — 5; 4; 7 units on a scale

Primary: Oswestry Disability Index — 9.8; 6.6 units on a scale

Primary: Participant-reported "Flares" of Low Back Pain (Aim 1) — 7.3 Mean flares per year

Primary: Lower Back Strength-Extension — 54.5; 50.2; 49.2; 57.5 kg-Force

Primary: Numerical Rating Scale (0-10), an Interval Pain Scale, on Which 0 Indicates no Pain and 10 Indicates the Worst Pain Imaginable — 7.1; 5.8 units on a scale

Primary: Change in Pain: Visual Analog Scale (VAS) — 2.1 units on a scale (centimeters)

Primary: Difference in the Proportion of Primary Outcome Successes Between Treatment Groups — 27; 9 participants — p=<0.00001

Primary: Change in Functional Impairment as Measured by the Roland Morris Disability Questionnaire — 11; 11 units on a scale

Primary: Change From Baseline to 11 Weeks in Oswestry Disability Scale (0-100%) — -11.06; -9.10 units on a scale — p=<.0001

Primary: Change in Oswestry Disability Index From Baseline to 10 Weeks — -8.8; -6.1 Units on a scale — p=0.02

Primary: Change From Baseline in Oswestry Disability Scale (0-100%) — -8.26; -7.75; -8.00; -9.48 units on a scale

Primary: Change From Baseline to Day 5 in Functional Impairment — 11.9; 9.4; 10.9 score on a scale

Primary: Change From Baseline in Oswestry Disability Index — -8.8; -17.0; -17.0; -22.4 units on a scale

Primary: Participants' Level of Low Back Pain-associated Disability as Assessed by Roland Morris Disability Questionnaire (RMDQ) — -1.29; -0.08 score on a scale — p=<0.05

Primary: Pain Assessed on a 10-point Numeric Pain Scale — 6.55; 6.68; 4.63; 5.13 cm

Primary: Functional Impairment as Measured on the Roland Morris Disability Questionnaire — 10.9; 9.4; 8.1 units on a scale

Primary: Sum of Pain Intensity Difference (SPID) for Low Back Pain - Summary Statistics at 120 Hours (With Imputation) — 264.6; 264.0 Units on a scale — p=0.9703

Primary: Change in Back-related Disability at 6-month Post Randomization (Continuous) — -2.1; -3.1; -3.6 change in score from baseline on scale — p=.024

Primary: Change From Baseline in Daily Low Back Pain Intensity (LBPI) Score as Measured by an 11-point Numeric Rating Scale (NRS) at Week 4 — -1.19; -1.03; -1.45 units on a scale

Primary: Quebec Back Pain Disability Scale — 27.9; 27.9; 16.7; 20.3 score on a scale

Primary: Modified Oswestry Disability Index — 23.46; 24.26 score on a scale

Primary: Leg Length Inequality — 0.3; 0.58 centemeter

Primary: Percent of Maximal Voluntary Isometric Contraction (%MVIC) — 226.41; 250.51; 162.47; 205.82 % of Max Voluntary Isometric Contraction

Primary: Number of Participants With 20% Reduction in Pain on the NRS Pain Intensity Scale — 5; 15; 21 Participants — p=1.0

Primary: Oswestry Low Back Pain Disability Index — -16.0; -8.9; -9.5 units on a scale — p=0.009

Primary: Visual Analogue Scale of Pain — 47.3; 45.2 units on a scale

Primary: Change in Pain Disability - Roland Morris Disability Questionnaire (RMDQ) Score — 8.7; 10.1; 6.4 score on a scale