Clinical Trial Search

Primary: Severity of Nasal Obstruction Symptoms at Baseline and Week 12 as Measured by the Total Clinical Score — 3.89; 1.26 Score on a scale

Primary: Change From Baseline in Adenoid/Choana (A/C) Index Grade — 0.3; 0.2; 0.4; 0.3 Score on a Scale

Primary: Change in Number of Subjects Without Oxygenation Abnormalities — 12; 10 Participants — p=0.54

Primary: Improvements in Attention/Executive Domain Index of the Developmental Neuropsychological Assessment (NEPSY) From Baseline to 7 Months. — 7.1; 5.1 units on a scale — p=0.16

Primary: Quality of Life (QoL) Outcomes Between Adenoidectomy + Maxillary Sinus Irrigation With or Without the Use of Balloon Dilation or Maxillary Sinus Ostia. — 2.48; 2.5…

Primary: Change in Behavioral Index After 6 Months of CPAP or No-CPAP — -2.7; .9; -1.2 T score — p=0.07

Primary: Change From Baseline to 12 Months in Caregiver-reported Behavior Rating Inventory of Executive Function (BRIEF) Global Executive Composite (GEC) T Score — -1.90; -3.08…

Primary: Ability to Tolerate Measured by Percent of Participants With Protocol Goal — 50 percent of participants

Primary: Lactobacillus Rhamnosus GG in Middle Ear Effusion and Adenoid Tonsil — 4; 1 Samples — p=0.05

Primary: Number of CD25 Pos/FoxP3 Positive Cells — 12.7; 14.6 cells per High power field (HPF)

Primary: Median Change in Apnea-hypopnea Index (AHI) — 3.8; 8.0 events per hour of sleep — p=.590

Primary: Healthcare Utilization — 5; 16; 5; 8 participants

Primary: Improvement in NOSE Score — 54.8 units on a scale — p=<0.0001

Primary: Requirement of Oxymetalozine Rescue for Ear Pain During Hyperbaric Therapy Compression — 8; 11 Participants

Primary: Change in Anthropometric Measures Over Time — 1.97; -0.61; 1.39; 1.22 Z-score

Primary: Change in NOSE Score — -44.5 units on a scale

Primary: Number of Subjects With Complete Normalization of Abnormal Tympanometry, Regardless of Additional Treatment — 7; 12 participants — p=0.18

Primary: Average Pain Score — 0 pain score

Primary: Effectiveness of Oxymetazoline in the Treatment of Rhinitis With Persistent Nasal Obstruction — 1.38; 1.67 units on a scale

Primary: Change in Subjective Nasal Scoring — 0.62; 1.53 score on a scale — p=0.013

Primary: Apnea Hypopnea Index (AHI) — 44.89; 44.65; 36.87 events per hour — p=<0.05

Primary: The Percentage of Patients Requiring at Least One Medical Intervention for Respiratory Events — 16; 29 Participants — p=<0.05

Primary: Obstructive Apnea Hypopnea Index — 7.69; 6.33 events per hour

Primary: Minimum Cross-Sectional Area (Amin) Proportion Measured Using Acoustic Rhinometry — 0.760; 0.742; 0.717; 0.795 ratio — p=0.302

Primary: Incidence of Unanticipated Serious Adverse Device Effects — 0 events

Primary: Number of Participants With Laryngospasm — 8; 6 Participants

Primary: Change of Respiratory Status Using the Modified Bronchiolitis Severity Score, in Children Using External Nasal Dilators as an Adjuvant to High Flow Nasal Cannula Oxygen…

Primary: Presence of Reflux in Patients With Polyposis — 15 participants

Primary: Cumulative Intra- and Postoperative Opioid Consumption — 0.209; 0.188 IV morphine milligram equivalent/kg — p=0.123

Primary: Number of Participants With Otomicroscopic Signs of Otorrhea in Either Ear — 13; 27; 15; 23 participants