Phase 2 N=212 Residual Effects of Intoxication on Student Performance
Alcoholic Intoxication · Neurobehavioral Manifestations
Primary: Self-reported Residual Effects of Heavy Drinking — 4.3; 1.93 scores on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=36 Cannabidiol Effects on Blood Alcohol Level and Intoxication
Alcohol Use Disorder
Primary: Breath Alcohol Concentration (BrAC) — 0.065; .067; .070 g/dL
Phase 1 N=33 Ability of Partial Inverse Agonist, Iomazenil, to Block Ethanol Effects in Humans
Active Ethanol and Active Iomazenil · Active Ethanol and Placebo Iomazenil · Placebo Ethanol and Active Iomazenil
Primary: Biphasic Ethanol Effects Scale (BAES) — 3.767; 3.935; 3.813; 3.194 score on a scale
Phase 4 N=15 Effect of Ethanol Intoxication on the Anti-Hypoglycemic Action of Glucagon
Type 1 Diabetes Mellitus
Primary: AOCGIR (Area Over the Curve for Glucose Infusion Rate) — 1996; 1981 mg*minute/dl
N/A N=112 Impaired Risk Awareness During Intoxication in DUI Offenders
Alcohol Use
Primary: Mean Number of Alcohol Binges — 3.36; 4.05; 2.69; 3.98 Alcohol Binges
N/A N=180 Intravenous Alcohol Administration Using BrAc Method in Healthy Subjects With and Without a Family History of Alcoholism
Alcoholism
Primary: Number of Drinks Felt Consumed at Baseline — 0; 0; 0; 0 drinks felt consumed
N/A N=10 Combined and Isolated Effects of Sleep Deprivation and Alcohol Intake on Exercise Performance in Humans.
Alcohol Intake · Sleep Deprivation
Primary: Aerobic Performance — 172; 173; 175; 176 bpm
Early Phase 1 N=30 Behavior Brain Responses
Alcohol Drinking · Drinking Behavior · Physiological Effects of Drugs
Primary: Change in Subjective Effects as Assessed by Score on "Feel Drug", "Feel High", "Like Drug", and "Want More" Subscales of the Drug Effects Questionnaire Across Sessions…
Phase 1 N=537 Alcohol Health Education Among College Drinkers
College Student Drinking
Primary: Alcohol Consumption — 16.929; 17.988; 18.039 drinks
Phase 2 N=44 Effect of Varenicline on Fixed-Dose Alcohol Administration in Participants With Alcohol Use Disorders
Alcohol Reactivity
Primary: Cognitive Function as Measured by Omissions on the CPT — 1.78; 1.28; 4.76; 0.98 Number of Omissions
N/A N=99 Alcohol Intervention for First Year College Students
Underage Alcohol Use
Primary: Acceptability-Number of Participants Who Found the Study Overall Favorable — 38; 0 Participants
Phase 2 N=32 Phase IIa Study of Fomepizole for Acetaldehyde Toxicity After Ethanol Exposure in Subjects With Altered Ethanol Metabolism
Aldehyde Dehydrogenase-2 (ALDH2) Deficiency
Primary: Number of Participants With Adverse Events (AEs), Serious AEs, and AEs Leading to Study Discontinuation — 13; 6; 8; 21 Participants
N/A N=365 Protective Behavioral Strategies and Brief Alcohol Interventions
Alcohol Consumption
Primary: Drinks Per Week — 12.55; 9.57; 13.74 drinks per week
N/A N=60 Acute Alcohol Response In Bipolar Disorder: a fMRI Study
Bipolar Disorder · Alcohol Drinking · Alcohol Use Disorder
Primary: Level of Intoxication (Subjective Response) on Each Condition Day After Drinking Relative to How They Felt When Arriving to the Lab on That Respective Day )Prior to…
N/A N=38 Alcohol and Neural Cardiovascular Control in Binge Drinkers
Binge Drinking
Primary: Sympathetic Nerve Activity Burst Frequency — 18; 20 Burst/Min — p=0.283
Early Phase 1 N=80 Alcohol, Behavior, and Brain Imaging
Alcohol Drinking · Binge Drinking · Drinking Behavior
Primary: Stop Signal Task (SST) — 255; 215 milliseconds
N/A N=75 Clinical Intervention in Alcohol Use Disorder
Alcohol Use Disorder · Eligible to go Into the MRI Scanner · Short-term Abstinence From Alcohol Use (2 Week Abstinent)
Primary: Intervention Effects on Brain Functional Connectivity — 0.05; 0.19 percentage of Blood Oxygenation Level De
N/A N=352 Brief Alcohol E-Interventions Study
Alcohol Drinking in College
Primary: Mean Drinks Per Day — .93; 1.15; .86; 1.38 Drinks per day — p=<.05
Phase 1 N=34 Mavoglurant in Alcohol Drinking
Alcohol Drinking
Primary: Abnormal Labs and Adverse Events — 9; 8; 0; 0 Participants
N/A N=24 Effects of Acetate and Alcohol on Brain Function
Cerebral Blood Flow · Brain Function
Primary: Change in Cerebral Blood Flow as Measured With Arterial Spin Labeling — 31.7; 26.9; 30.0; 25.0 cc/100 mg/min
N/A N=48 Alcohol Impaired Driving in the Natural Environment
Driving Under the Influence
Primary: Alcohol Impaired Driving Behavior — 67; 60; 36; 29 Count of driving episodes after drinking
N/A N=54 Manipulation of Breath Alcohol Tests: Can Specific Techniques Alter Blood Alcohol Concentration Readings?
Alcohol Concentration Values · Alcohol Intoxication
Primary: Percent Alcohol Concentration Measured by Breathalyzer — 0.099; 0.086; 0.099; 0.099 percent Breathalyzed alcohol content — p=<0.0001
N/A N=668 Prevalence of Chronic Inebriates to the Emergency Department and Suitability for Sobering House Services
Alcohol Intoxication
Primary: Intoxicated Patients Eligible for a Sobering House — 163 Participants
N/A N=20 Evaluating Perceived Fitness to Drive While Intoxicated
Alcohol Drinking · Alcohol Intoxication · Perception, Self
Primary: Participants' Perceived Fitness to Drive Measurement — 6.5; 4.6 units on a scale
N/A N=44 Satiety and Alcohol Challenge
Alcohol Drinking
Primary: Change in Alcohol Specific Satiety Score — -0.51; 4.85 score on a scale
N/A N=200 Feasibility and Effectiveness of a Specialized Brief Intervention for Hazardous Drinkers in an Emergency Department.
Alcohol Drinking
Primary: Proportion of Risky Drinkers Measured by AUDIT-C — 20; 39 Participants
N/A N=444 Brief Online Interventions for Alcohol Use
Alcohol Use Disorder
Primary: Alcohol Use — 19.4; 16.3; 15.3; 19.1 percentage heavy drinking days
N/A N=37 Biobehavioral Pathways Underlying Alcohol Use and Health
Alcohol Use Disorder · Liver Diseases
Primary: Percentage of Screen Eligible Who Enroll — 28; 5 Participants
N/A N=360 Alcohol Metabolism and Disease Risk in Asians
Healthy
Primary: Peak Number of Alcohol Drinks Consumed in a Day — 3.7; 4.2; 3.4; 3.0 drinks — p=.81
N/A N=55 Accuracy of Self-estimation of Blood Alcohol Concentration Compared to Object Values
Alcohol Intoxication
Primary: Change in Breath Alcohol Content Between the Estimated Level and the Actual Level as Measured by an Alco Sensor IV Device — 0.01; -0.01 percent blood alcohol content…