N/A N=59 Cognitive Training in the Treatment of AUD
Alcohol Use Disorder Cognitive Decline
Primary: Days of Heavy Alcohol Use Assessed by Weekly Time Line Follow-back and Breathalyzer — 5.49; 3.0 Days — p=<.05
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=37 Biobehavioral Pathways Underlying Alcohol Use and Health
Alcohol Use Disorder · Liver Diseases
Primary: Percentage of Screen Eligible Who Enroll — 28; 5 Participants
N/A N=90 Cognitive Remediation for Alcohol Use Disorder and Posttraumatic Stress Disorder
Alcohol Use Disorder · PTSD · Cognitive Dysfunction
Primary: The Revised Hopkins Verbal Learning Test — 47.71; 44.14 units on a scale
N/A N=75 Clinical Intervention in Alcohol Use Disorder
Alcohol Use Disorder · Eligible to go Into the MRI Scanner · Short-term Abstinence From Alcohol Use (2 Week Abstinent)
Primary: Intervention Effects on Brain Functional Connectivity — 0.05; 0.19 percentage of Blood Oxygenation Level De
Phase 2 N=12 Modafinil for the Treatment of Alcohol Use Disorders
Alcohol Use Disorder
Primary: Time to Relapse — 16; 43 days
Phase 2 N=44 Effect of Varenicline on Fixed-Dose Alcohol Administration in Participants With Alcohol Use Disorders
Alcohol Reactivity
Primary: Cognitive Function as Measured by Omissions on the CPT — 1.78; 1.28; 4.76; 0.98 Number of Omissions
N/A N=60 Acute Alcohol Response In Bipolar Disorder: a fMRI Study
Bipolar Disorder · Alcohol Drinking · Alcohol Use Disorder
Primary: Level of Intoxication (Subjective Response) on Each Condition Day After Drinking Relative to How They Felt When Arriving to the Lab on That Respective Day )Prior to…
N/A N=16 Pilot Study on Training Emerging Adults Skills in Navigating College
Alcohol Abuse · Cognitive Deficit in Attention
Primary: Participant Retention — 85.71; 88.89 percentage of participants
N/A N=77 Cognitive Retraining and Brain Stimulation for Alcohol Use
Binge Drinking
Primary: Drinks Per Drinking Day — 6.1; 6.8; 6.6; 7.5 drinks per drinking day
N/A N=19 Compensatory Cognitive Training Via Telehealth for Veterans With Alcohol Use Disorders
Alcohol Use Disorder
Primary: Recruitment Rate — 19 Participants
N/A N=134 Records for Alcohol Care Enhancement
Alcohol Use Disorder (AUD)
Primary: Percent of New Alcohol Use Disorder (AUD) Diagnosis Episodes That Meet Criteria for AUD Treatment Engagement Among Patients With a New AUD Diagnosis Who Are Empaneled to…
Phase 2 N=52 Ibudilast and Withdrawal-Related Dysphoria
Alcohol Use Disorder
Primary: Negative Affect — 2.91; 2.47 units — p=.62
Phase 1 N=26 Citalopram Effects on Craving and Dopamine Receptor Availability in Alcoholics
Alcohol Dependence
Primary: Craving for Alcohol in Alcohol Dependence With Citalopram Compared to Placebo — 21; 30.4; 10.8; 10.6 score on a scale
Phase 2 N=27 Effects of Cannabidiol in Alcohol Use Disorder
Alcohol Use Disorder
Primary: Trough CBD Plasma Levels — 0; 0.7 CBD (ng/mL)
N/A N=124 Decreasing the Temporal Window in Individuals With Alcohol Use Disorder
Alcohol Use Disorder
Primary: Delay Discounting (DD) Rates — -4.69; -5.15; -4.92; -5.58 ln(K-value) — p=.60
N/A N=9 Genetic and Neural Factors in Alcohol-Related Cognition
Alcohol Abuse
Primary: Changes in Alcohol-influenced Behavior — 1.56; 1.49 units on a scale
N/A N=84 Mindfulness-Based Intervention and Transcranial Direct Current Brain Stimulation to Reduce Heavy Drinking
Alcohol Drinking · Alcohol Intoxication · Alcoholism
Primary: Drinks Per Drinking Day — 5.12; 5.64; 4.95; 5.48 drinks per drinking day
Phase 2 N=33 Transcranial Direct Current Stimulation Over Dorsolateral Prefrontal Cortex in Alcoholism
Alcohol Dependence · Executive Dysfunction · Abnormal Craving for Drugs
Primary: Use of Alcohol — 15; 8 participants
N/A N=131 Neurobiological Responses in Alcoholism and Early Trauma
Alcohol Use Disorder · Early Trauma Complications
Primary: Brain Response — .015; .010; -.013; .08 unitless — p=<0.05
N/A N=11 Effect of Theta Burst Stimulation on Alcohol Cue Reactivity
Alcohol Drinking · Alcohol Use Disorder · Trauma Injury
Primary: Behavioral Outcomes: Change in the k-Value, a Measure of Delay Discounting of Alcohol — -0.12; -7.42 Change in k-value
N/A N=46 HCV and Co-morbid Alcohol Use Disorders: A Translational Investigation of Antiviral Therapy Outcomes on CNS Function
Hepatitis C · Alcohol Use Disorder
Primary: Changes in Neuropsychological Assessment Battery (NAB) Attention Module Scores — 10.99; 0.31; 6.35 Units on a scale
N/A N=102 Increasing the Temporal Window in Individuals With Alcohol Use Disorder
Alcohol Use Disorder
Primary: Delay Discounting (DD) Rates (Studies 1 and 2) — -5.33; -6.03; -4.94; -5.79 ln(K-value)
N/A N=3 Pilot Human Laboratory Study of Alcohol Approach Bias Modification (AABM) for Alcohol Use Disorder (AUD)
Alcohol Use Disorder
Primary: Recruitment Feasibility — 3 Participants
N/A N=60 A Response Modulation Hypothesis of Socioemotional Processing Associated With Alcohol Use Disorder
Healthy Volunteers · Alcohol Drinking Related Problems · Alcohol-Related Disorders
Primary: Alcohol Attention Bias Signal - Stage 1 — 0.007121461; 0.135970228; -0.015216812; 0.112620872 Arbitrary units (A.U)
N/A N=140 Cost Effectiveness of Combined Contingency Management and Cognitive Behavioral Therapy for Alcohol Use Disorder
Alcohol Drinking · Veterans
Primary: Average Number of Heavy Drinking Days — 15.1; 15.9; 13.2; 11.3 days
N/A N=120 Coping Skills for Alcohol Use
Alcohol Drinking · Coping Skills
Primary: Alcohol Use-Peak Drinks — 4.71; 4.79 number of drinks — p=>.05
Phase 4 N=96 Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders
Alcohol Use Disorder · Bipolar Disorder · Schizoaffective Disorder Bipolar Type
Primary: Baseline-to-Exit Change in Drinks Per Drinking Day (TLFB) — -1.98; -2.82; -1.22 Standard Drinks per Drinking Day
N/A N=444 Brief Online Interventions for Alcohol Use
Alcohol Use Disorder
Primary: Alcohol Use — 19.4; 16.3; 15.3; 19.1 percentage heavy drinking days
N/A N=185 Pioglitazone for the Treatment of Alcohol Use Disorder
Alcohol Use Disorder
Primary: Heavy Drinking Days Per Week Change — -1.76; -2.3 Mean heavy drinking days per week
N/A N=75 Transdiagnostic CBT for Comorbid Alcohol Use and Anxiety Disorders
Alcohol Use Disorder · Anxiety Disorders
Primary: Mean Number of Drinks Consumed Per Week — 40.82; 29.62; 12.12; 23.86 Standard Drinking Units per Week — p=0.002