N/A N=37 Biobehavioral Pathways Underlying Alcohol Use and Health
Alcohol Use Disorder · Liver Diseases
Primary: Percentage of Screen Eligible Who Enroll — 28; 5 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=180 Intravenous Alcohol Administration Using BrAc Method in Healthy Subjects With and Without a Family History of Alcoholism
Alcoholism
Primary: Number of Drinks Felt Consumed at Baseline — 0; 0; 0; 0 drinks felt consumed
N/A N=360 Alcohol Metabolism and Disease Risk in Asians
Healthy
Primary: Peak Number of Alcohol Drinks Consumed in a Day — 3.7; 4.2; 3.4; 3.0 drinks — p=.81
N/A N=303 The Impact of Alcohol Consumption on Tuberculosis Treatment Outcomes
Tuberculosis · Alcohol Consumption · Treatment Adverse Effect
Primary: Time to Culture Conversion — 5.6; 5.4; 5.5 weeks
N/A N=75 Clinical Intervention in Alcohol Use Disorder
Alcohol Use Disorder · Eligible to go Into the MRI Scanner · Short-term Abstinence From Alcohol Use (2 Week Abstinent)
Primary: Intervention Effects on Brain Functional Connectivity — 0.05; 0.19 percentage of Blood Oxygenation Level De
N/A N=134 Records for Alcohol Care Enhancement
Alcohol Use Disorder (AUD)
Primary: Percent of New Alcohol Use Disorder (AUD) Diagnosis Episodes That Meet Criteria for AUD Treatment Engagement Among Patients With a New AUD Diagnosis Who Are Empaneled to…
N/A N=125 Characterizing the Effects of Family History of Alcoholism on Alcohol Analgesia
Effects of Family History of Alcoholism and Sex on Alcohol Analgesia
Primary: Heat Pain Threshold — 43.56; 43.63; 42.28; 43.94 degrees celsius — p=.92
N/A N=63 The Efficacy of CBT-I in Alcoholics & Its Effects on Remission & Relapse
Insomnia
Primary: Change in Insomnia Severity Index - Total Score — -10.71; -8.84; -8.51; -9.30 units on a scale
Phase 2 N=56 Medication Development in Alcoholism: Investigating Glucocorticoid Antagonists
Alcoholism
Primary: Craving to Drink — 36.5; 42.9 units on a scale — p=.003
Phase 1 N=26 Citalopram Effects on Craving and Dopamine Receptor Availability in Alcoholics
Alcohol Dependence
Primary: Craving for Alcohol in Alcohol Dependence With Citalopram Compared to Placebo — 21; 30.4; 10.8; 10.6 score on a scale
N/A N=33 Alcohol Biosensor Monitoring for Alcoholic Liver Disease
Alcohol Use, Unspecified
Primary: Alcohol Use — 7.4; 5.3; 4.4 drinks per episode
Phase 2 N=46 Varenicline to Reduce Alcohol Consumption in Heavy Drinkers
Alcohol Drinking
Primary: Alcohol Consumption — 92.0; 77.3 mg/%
N/A N=131 Neurobiological Responses in Alcoholism and Early Trauma
Alcohol Use Disorder · Early Trauma Complications
Primary: Brain Response — .015; .010; -.013; .08 unitless — p=<0.05
Phase 2 N=50 Medication Development in Alcoholism: Investigating PPAR Agonists
Alcoholism
Primary: Visual Analog Scale of Craving to Drink at 1 Week Following Administration of Fenofibrate or Placebo During the Double-Blind Period — 8.94; 10.37; 9.83; 11.03 units on a…
Phase 2 N=51 Medication Development in Alcoholism: Apremilast Versus Placebo
Alcohol Use Disorder
Primary: Craving to Drink — 33.84; 28.31 score on a scale — p=0.36
Phase 3 N=81 Interdisciplinary Study of A Novel Anticonvulsant in Alcoholism
Alcohol Dependence
Primary: Average Standard Drinking Units Per Day — 4.50; 4.48 standard drinking units per day — p=.98
Phase 4 N=163 A Randomized Clinical Trial of Alcohol Care Management
Alcohol Dependence
Primary: Treatment Engagement — 36; 9 percentage of participants engaged
N/A N=60 Acute Alcohol Response In Bipolar Disorder: a fMRI Study
Bipolar Disorder · Alcohol Drinking · Alcohol Use Disorder
Primary: Level of Intoxication (Subjective Response) on Each Condition Day After Drinking Relative to How They Felt When Arriving to the Lab on That Respective Day )Prior to…
Phase 3 N=80 Effects of Omegas 3 and 6 on Alcohol Dependence
Alcohol Dependence
Primary: "Drinking Days" in the Previous Month — 19.54; 15.18; 17.75; 22.11 Days — p=<0.001
Phase 2 N=33 Transcranial Direct Current Stimulation Over Dorsolateral Prefrontal Cortex in Alcoholism
Alcohol Dependence · Executive Dysfunction · Abnormal Craving for Drugs
Primary: Use of Alcohol — 15; 8 participants
Phase 2 N=27 Collaborative Care for Alcohol Use Disorders in the Patient-centered Medical Home
Alcohol-Related Disorders · Alcohol Drinking · Alcoholism
Primary: Weekly Change in Drinking — -11.4; -22.2; -39.6; -29.3 score on a scale
Phase 2 N=111 Family History Study of Alcohol Consumption Using Memantine
Alcohol Drinking
Primary: Number of Drinks Consumed on Day 7 — 5.84; 5.61; 6.21 standard drinks
N/A N=94 Pharmacogenetics of Alcohol: Treatment Implications
Alcohol Related Disorders · Alcoholism · Alcohol Abuse
Primary: Breath Alcohol — 0.001; 0.075; 0.001; 0.071 gr/dL — p=0.28
Phase 2 N=150 Gabapentin Treatment of Alcohol Dependence
Alcoholism · Alcohol Dependence
Primary: Drinking — 6; 8; 2 participants — p=<0.04
Phase 2 N=60 Do Treatments for Smoking Cessation Affect Alcohol Drinking?
Alcohol Drinking
Primary: Number of Drinks Consumed — 2.1; 2.05; 1.5; 1.7 number of drinks
Phase 3 N=129 A New Pharmacotherapy for Alcohol Dependence: Olanzapine
Alcohol Dependence
Primary: Drinks Per Drinking Day — 8.7; 8.9; 9.2 Drinks per drinking day
Phase 2 N=120 Addressing Heavy Alcohol Use Consumption With Kudzu
Alcohol Use Disorder · Sexually Transmitted Diseases
Primary: Number of Binge Drinking Days — 2.15; 2.15; 1.94; 2.21 number of days
N/A N=185 Pioglitazone for the Treatment of Alcohol Use Disorder
Alcohol Use Disorder
Primary: Heavy Drinking Days Per Week Change — -1.76; -2.3 Mean heavy drinking days per week
Phase 2 N=151 Concurrent Alcohol and Smoking Treatment: Effects on Alcohol Relapse Risk
Tobacco Use Cessation · Alcohol-related Disorders
Primary: Smoking Abstinence — 20; 1 participants — p=<.01
N/A N=49 Bilateral Prefrontal Modulation in Alcoholism
Drug Addiction · Executive Dysfunction
Primary: Craving — 5.522; 3.818; 4.391; 4.136 scores — p=< 0.01