N/A N=56 AMPLEX Ankle Fusion and Hindfoot
Arthrodesis Surgery Involving the Hindfoot or Ankle
Primary: Proportion of Subjects Who Met All Five Criteria for Subject Performance Composite (SPC) Endpoint — 79.5; 35.3 percentage of subjects
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=273 Treatment Outcomes for Ankle Arthritis
Osteoarthritis
Primary: Musculoskeletal Functional Assessment (MFA) — -12.5; -15.0 units on a scale
N/A N=48 Prospective Subtalar, Double, or Triple Arthrodesis Study With CCS Screws
Post-traumatic Osteoarthritis, Unspecified Ankle and Foot · Localized, Primary Osteoarthritis of the Ankle and/or Foot
Primary: Number of Participants With Intraoperative Complications — 0 Participants
N/A N=13 Compression Nail for Tibiocalcaneal Arthrodesis
Subtalar Arthritis · Ankle Arthritis
Primary: Pain Assessment — 52.73; 33.00; 17.00; 21.25 score on a scale
N/A N=50 Agility LP Ankle Arthroplasty Outcomes
Rheumatoid Arthritis of Ankle · Osteoarthritis of Ankle · Traumatic Arthritis of Ankle
Primary: Assessment of Functional Outcomes Following Agility LP Ankle Replacement — 37.67; 37.07 Degrees
N/A N=11 Do Rocker Bottom Shoes and Ankle-Foot Orthoses Reduce Pain and Improve Mobility for Ankle Osteoarthritis Patients
Ankle Osteoarthritis · Healthy Ankles
Primary: Daily Step Count (# Steps) — 3453; 2399; 3453; 2745 steps
N/A N=233 A Multicenter Randomized Trial Comparing Antiglide and Lateral Plate Fixation in Ankle Fractures
Ankle Injuries
Primary: Percentage of Nonpalpable Hardware — 71; 55; 64; 66 percentage of participants
N/A N=98 Prospective Randomized Evaluation of a Two and Three Piece Total Ankle Replacement
Ankle Osteoarthritis
Primary: Pain Following a Total Ankle Replacement as Measured by the Visual Analog Scale (VAS) for Pain — 67.0; 71.3; 16.7; 18.6 mm — p=0.29
N/A N=22 Iterative Design of Custom Dynamic Orthoses to Reduce Articular Contact Stress
Ankle Fractures · Post-traumatic Osteoarthritis · Osteoarthritis Ankle
Primary: Joint Contact Stress Time Exposure (Model Estimated) — 4.44; 3.97; 4.08; 4.25 MPa-s/gait cycle
N/A N=23 Weightbearing Assessment of Tarsal Instability
Adult-acquired Flatfoot Disorder (AAFD)
Primary: Change in Joint Motion Between Touch-down Bearing Navicular and Full-weight Bearing Navicular — 3.56; 4.36; -0.1666; -0.170 mm
N/A N=15 ViviGen Cellular Bone Matrix for Hindfoot or Ankle Arthrodesis
Ankle Deformity · Ankle Arthritis
Primary: Union Rates — 23 joints fused
N/A N=21 Internal Brace Augmented Anterior Inferior Tibiofibular Ligament Repair: Post-operative Syndesmotic Volumes.
Syndesmotic Injuries · Ligament Rupture · Bimalleolar Fractures
Primary: Syndesmotic Volumetric Ratio — 1.2; 1.1 Volumetric Ratio
Phase 3 N=30 Effects of CHONDRON (Autologous Chondrocytes) With Ankle Cartilage Defect
Articular Cartilage Defects of Ankle Joint
Primary: Average Change From Baseline in American Orthopedic Foot and Ankle Society(AOFAS) at 12 Months Post-surgery — 16.93 scores
N/A N=40 Cryoneurolysis for Improvements in Pain, ADL and QOL in Patients With Ankle Osteoarthritis
Ankle Osteoarthritis
Primary: FAOS - PAIN — 20.8 score on a scale
N/A N=25 Study of Cingal® for Symptomatic Relief of Osteoarthritis of Ankle Joint
Osteoarthritis, Ankle
Primary: Numerical Rating Scale (NRS) Pain on Walking — -3.84 units on a scale — p=<0.0001
Phase 4 N=100 Efficacy of Tranexamic Acid in Foot and Ankle Surgeries
Foot and Ankle Surgeries · Bunion
Primary: Total Estimated Blood Loss — 40.41; 18.75 ml
N/A N=299 Augment® Injectable Bone Graft Compared to Autologous Bone Graft as a Bone Regeneration Device in Hindfoot Fusions
Degenerative Joint Disease · Congenital Deformity · Arthritis
Primary: Pain on Weight Bearing — 71.0; 70.7; 29.5; 28.2 units on a scale
N/A N=80 Saphenous Nerve Block for Foot and Ankle Surgery
Saphenous Nerve Block
Primary: Block Success — 18; 22 participants — p=0.25
N/A N=50 Ankle Foot Orthosis Comparative Effect
Foot Injuries and Disorders
Primary: PROMIS Patient Reported Outcomes for Physical Function — 44.78; 45.02 score on a scale
N/A N=9 Computed Tomography for Evaluating Supination-external Rotation Type Ankle Fractures
Supination-external Rotation Ankle Fractures
Primary: Medial Clear Space Distance in the Ankle Joint — 1.41 mm
N/A N=414 Augment® Bone Graft (Formerly GEM OS™1 Bone Graft) Compared to Autologous Bone Graft in Foot and Ankle Fusions
Foot Fusion
Primary: Subjects Fused at 24 Weeks (as Determined by CT Assessment) — 85; 159 Participants
Phase 3 N=24 Allograft Transplantation in the Treatment of Osteoarthritis of the Metatarsophalangeal (MTP) Joint of the Great Toe
Osteoarthritis
Primary: Allograft Stability — 0
Phase 4 N=100 Efficacy of Multimodal Periarticular Injections in Operatively Treated Ankle Fractures
Pain, Postoperative · Ankle Fractures
Primary: Change in Post-operative Visual Analog Pain Scores (VAS) — 42; 52; 41; 50 0 to 100 score on a scale
Phase 4 N=14 Anesthesia for Pain After Ankle Fracture Surgery
Chronic Pain · Ankle Fracture Surgery · Regional Anesthesia
Primary: Pain Score at 12 Months - Experimental Group vs. Control Group — 36.33; 44.00 units on a scale — p=0.1269
N/A N=148 A Longitudinal Outcomes Study of the Subchondroplasty® Procedure in the Foot/Ankle
Insufficiency Fractures · Stress Fracture · Stress Fracture, Ankle, Foot and Toes
Primary: Foot Function Index-Revised (FFI-R) Short Form Score at 24 Months — 42.8; 43.0; 39.6 Percentage scale
N/A N=20 Reduction and Fixation of Metatarsal Neck Fracture by Metaizeau's Technique
Displaced Metatarsal Neck Fracture
Primary: Time of Union — 5.8 weeks
N/A N=64 Mid-term Outcomes of First MTP Arthroplasty With Primus™ FGT Implant.
Hallux Limitus of Left Great Toe · Rheumatoid Arthritis · Arthritis of 1st Metatarsophalangeal Joint
Primary: AOFAS Hallux-MTP-IP Score - Overall — 88.9 units on a scale
N/A N=100 Associated Joint Pain With Controlled Ankle Movement (CAM) Walker Boot Wear
Pain · Ankle Injuries
Primary: The Presence and Severity of Secondary Site Pain — 31 Participants
N/A N=11 Platelet Rich Plasma Injection in Pilon Fractures
Fracture
Primary: Intra-articular Inflammatory Biomarkers at the Time of Definitive Fixation — 54.89; 163.01; 2479.17; 2511.32 pg/ml
N/A N=25 MONOVISC for Ankle Joint Pain Relief Due to Osteoarthritis
Osteoarthritis Ankle
Primary: Numerical Rating Scale (NRS) Pain on Walking — -3.00 score on a scale — p=<0.0001