Phase 4 N=24 Vilazodone for Separation Anxiety Disorder
Separation Anxiety Disorder
Primary: Clinical Global Impression-Improvement Scale — 7; 4 Participants — p=.064
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N/A N=136 Parent-based Treatment for Youth With Anxiety and Obsessive-compulsive Disorder
Obsessive-Compulsive Disorder in Children · Social Anxiety Disorder of Childhood · Obsessive-Compulsive Disorder in Adolescence
Primary: Pediatric Anxiety Rating Scale — 10.86; 10.96 score on a scale
N/A N=167 Psychotherapy for Anxiety in Children With Autism Spectrum Disorder
Autism Spectrum Disorders · Autism · Asperger's Syndrome
Primary: Change From Baseline in Anxiety Severity on the Pediatric Anxiety Rating Scale After 16 Weeks of Treatment. — 3.43; 3.47; 3.28; 2.13 units on a scale
N/A N=75 Assessing Mechanisms of Anxiety Reduction in Animal-assisted Interventions
Social Anxiety Disorder · Social Anxiety · Social Anxiety Disorder of Childhood
Primary: Self-reported Affective Experience — 10.19; 10.00; 10.28; 8.33 units on a scale — p=.723
N/A N=40 Family-Based Prevention Program for Childhood Anxiety
Anxiety Disorders
Primary: Number of Children With Child Anxiety Diagnosis — 20; 20 participants
N/A N=64 Early Intervention for Children at Risk for Anxiety
Anxiety Disorder
Primary: Number of Responders Based on Clinician Global Impression-Anxiety Improvement — 20; 9 Participants — p=<.05
N/A N=214 Brain Response Associated With Parent-based Treatment for Childhood Anxiety Disorders
Anxiety Disorder of Childhood · Separation Anxiety Disorder of Childhood · Social Anxiety Disorder of Childhood
Primary: Change From Baseline Anxiety Severity on the Pediatric Anxiety Rating Scale (PARS) at Week 12. — -11.82; -6.29; -8.47; -6.54 score on a scale
N/A N=56 Anxiety in Older Veterans
Anxiety Disorders
Primary: Change in Anxiety Symptoms — 1.77; -2.42 units on a scale
N/A N=50 Threat Interpretation Bias as Cognitive Marker and Treatment Target in Pediatric Anxiety
Anxiety Disorders
Primary: Change in Linguistic Interpretation Bias as Assessed by the Word-sentence Association Paradigm for Youth (WSAP-Y) — 19.77; 47.40 score on a scale
N/A N=87 Parent-Led Cognitive-Behavioral Teletherapy for Anxiety in Youth With ASD
Cognitive Behavioral Therapy · Autism Spectrum Disorder · Anxiety Disorders
Primary: 6-item Pediatric Anxiety Rating Scale — 11.35; 10.26 Score on a scale
N/A N=90 Treatment of Social Anxiety Disorder and Selective Mutism
Social Anxiety Disorder · Selective Mutism
Primary: Change in Clinical Severity Ratings (CSR) of SAD & SM on the Anxiety Disorders Interview Schedule - Parent Version (ADIS-P) — -1.26; -1.65; -1.51; -1.24 units on a scale…
N/A N=59 A Single-Session Intervention for Families on Waitlists for Child Anxiety Treatment
Anxiety Disorders
Primary: Screen for Child Anxiety Related Emotional Disorders - Parent Version at Posttreatment — 35; 30 units on a scale
Phase 2 N=83 SPD503 in Subjects Aged 6-17 Years With Generalized Anxiety Disorder (GAD), Separation Anxiety Disorder (SAD), or Social Phobia (SoP)
Generalized Anxiety Disorder (GAD) · Anxiety, Separation · Phobia, Social
Primary: Change From Baseline in Systolic Blood Pressure at Up to 12 Weeks — -1.7; -2.3 mmHg
N/A N=58 Sleep and Emotional Memory in Peripubertal Anxiety
Anxiety
Primary: Scores on the Lure Generalization Index (a Behavioral Measure of Generalization) — .24; .26; .14; .10 units on a scale — p=<.046
N/A N=15 Assessing Visual Processing in High Anxiety
Anxiety
Primary: Tolerability of the Micro Expression Training Task in Individuals With High Anxiety — 5; 6 Participants
N/A N=117 Cartoon Distraction and Parental Presence on Anxiety in Pediatric Anesthesia
Anxiety, Separation · Psychomotor Agitation
Primary: Modified Yale Preoperative Anxiety Scale Scores at Baseline, Arrival in Operating Room, and Inhalation Induction — 28.4; 28.4; 23.4; 23.4 units on a scale
Phase 3 N=45 Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders
Autism · Asperger's Syndrome · Generalized Anxiety Disorder
Primary: Pediatric Anxiety Rating Scale (Measures the Severity of Anxiety Symptoms) — 16.33; 17.62; 11.58; 16.05 units on a scale
N/A N=136 Effectiveness of a Family-Based Treatment for Preventing Anxiety Disorders in At-Risk Children
Anxiety Disorders
Primary: Anxiety Disorders Interview Schedule for Diagnostic and Statistical Manual for Psychological Disorders-IV, Child and Parent Versions (C/P-ADIS) — 19; 3 participants with…
Phase 3 N=265 Transdiagnostic Cognitive Behavioral Treatment for Anxiety
Anxiety Disorders
Primary: CRIS-EPS: Comparison of Extent of Participation Scores Among iCBT, sCBT, and TAU Groups From Baseline to 1, 3, and 6 Month Follow Ups — 4.21; 4.18; 4.17; 4.52 score on a…
N/A N=151 Clinical Management of Anxiety and Access to Health Care
Dental Anxiety
Primary: Change in Modified Dental Anxiety Scale — 19.5; 19.6; 15.4; 17.6 units on a scale — p=<0.05
N/A N=32 Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety
Autism · Asperger's Syndrome · Pervasive Developmental Disorder Not Otherwise Specified
Primary: Pediatric Anxiety Rating Scale — 7.79; 15.06 units on a scale
N/A N=110 Kidpower Camp - Structured Games or Playgroup
Anxiety Disorders
Primary: Change in Error Related Negativity (ERN) — -0.169; -1.192 millivolts
N/A N=21 Neurally Targeted Cognitive Training to Augment CBT Outcomes in Pediatric Anxiety
Anxiety Disorders
Primary: Change in Brain Activation and Connectivity in the Task-control Network (TCN) — 0.020; -0.206; 0.305; -0.004 Arbitrary Units
N/A N=31 Cognitive Behavioral Therapy for Anxiety Disorders in Adolescents With Autism
Autism · Asperger's Syndrome · Pervasive Developmental Disorder Not Otherwise Specified
Primary: Pediatric Anxiety Rating Scale — 10.94; 13.93 units on a scale
Phase 3 N=488 Child and Adolescent Anxiety Disorders (CAMS)
Anxiety Disorders · Social Phobia · Generalized Anxiety Disorder
Primary: Clinical Global Impression - Improvement Scale — 54.9; 59.7; 80.7; 23.7 percentage of participants
N/A N=210 Effects of Maternal Interpretation Biases on Child Anxiety and Related Responses
Anxiety Disorders
Primary: Word Sentence Association Paradigm — 0.37; 0.52; 0.27 units on a scale
N/A N=918 Expectation of Unpleasant Events in Anxiety Disorders
Anxiety Disorders
Primary: Change in Percent of Correct Button Presses During Threat Compared to the Safe Condition (AAST) — -0.016; 0.008 Percentage of accurate responses
Phase 2 N=33 Cognitive Behavioral Therapy (CBT) for Anxiety Disorders in Autism: Adapting Treatment for Adolescents
Anxiety Disorders in Youth With Autism, Asperger's Syndrome, and Pervasive Developmental Disorder Not Otherwise Specified
Primary: Pediatric Anxiety Rating Scale. — 11.62; 14.04 units on a scale — p=.04
N/A N=37 A Unified Treatment for Anxiety Disorders
Emotional Disorders · Anxiety Disorders
Primary: Anxiety Disorders Interview Schedule for DSM-IV — 5.23; 5.09; 3.18; 5.14 score on a scale
N/A N=76 Stepped-Care Cognitive-Behavioral Treatment for Youth With ASD and Anxiety
Cognitive Behavioral Therapy · Autism Spectrum Disorder · Anxiety Disorders
Primary: 7-item Pediatric Anxiety Rating Scale — 11.87 Score on a scale