N/A N=1,063 Brain Imaging Changes in Fear and Anxiety
Anxiety Disorders · Fear
Primary: Average Correlations Between Average Time Series - Left & Right Hemisphere of the Brain — 0.9; 0.92 correlation coefficient (r) — p=< 0.001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=918 Expectation of Unpleasant Events in Anxiety Disorders
Anxiety Disorders
Primary: Change in Percent of Correct Button Presses During Threat Compared to the Safe Condition (AAST) — -0.016; 0.008 Percentage of accurate responses
N/A N=1,418 Effects of Arousal and Stress in Anxiety
Healthy Volunteers
Primary: Go Correct Hits Followed by Button Press — 90.9; 91.6 Percentage of correct responses
Phase 4 N=60 Cognitive vs. Emotional Psychopharmacological Manipulations of Fear vs. Anxiety
Anxiety Disorder
Primary: Magnitude of Startle Reflex During Safe Condition — 42.2880893; 42.39801; 43.61243; 44.1886408 millivolts (mV)
N/A N=56 Anxiety in Older Veterans
Anxiety Disorders
Primary: Change in Anxiety Symptoms — 1.77; -2.42 units on a scale
Phase 4 N=172 Pilot Study of Pharmaceutical and Behavioral Interventions to Treat Anxiety Disorders
Posttraumatic Stress Disorder · Anxiety Disorder
Primary: Change From Baseline Skin Conductance Response — .06; .17; -1.27; -.04 microSiemens — p=>.05
N/A N=151 Clinical Management of Anxiety and Access to Health Care
Dental Anxiety
Primary: Change in Modified Dental Anxiety Scale — 19.5; 19.6; 15.4; 17.6 units on a scale — p=<0.05
N/A N=15 Assessing Visual Processing in High Anxiety
Anxiety
Primary: Tolerability of the Micro Expression Training Task in Individuals With High Anxiety — 5; 6 Participants
N/A N=606 Stress, Sex, and the Generalization of Fear
Psychological Stress
Primary: Fear-potentiated Startle Responses to the CS+ and CS- During Acquisition — 52.059; 19.162; 44.388; 9.732 Fear-potentiated startle (microvolts) — p=0.453
N/A N=51 Identifying Decision Making Parameters in Healthy Volunteers and Anxiety Patients
Anxiety · Healthy Volunteers
Primary: Difference in Learning Rate — 0.009; 0.0058 unitless
N/A N=50 Threat Interpretation Bias as Cognitive Marker and Treatment Target in Pediatric Anxiety
Anxiety Disorders
Primary: Change in Linguistic Interpretation Bias as Assessed by the Word-sentence Association Paradigm for Youth (WSAP-Y) — 19.77; 47.40 score on a scale
N/A N=18 Novel Anxiety Treatment
Cognitive Training · Anxiety Disorders
Primary: Change in Symptoms of Anxiety Based on Screen for Anxiety and Related Disorders (SCARED) Parent Report at Baseline and Post Assessment — -20.4; -21.12 units on a scale
N/A N=167 Psychotherapy for Anxiety in Children With Autism Spectrum Disorder
Autism Spectrum Disorders · Autism · Asperger's Syndrome
Primary: Change From Baseline in Anxiety Severity on the Pediatric Anxiety Rating Scale After 16 Weeks of Treatment. — 3.43; 3.47; 3.28; 2.13 units on a scale
N/A N=35 Reducing Anxiety and Stress in Primary Care Patients
Anxiety
Primary: Generalized Anxiety Disorder-7 at Post-Assessment — 12.5; 12.0; 4.6; 9.1 score on a scale — p=0.035
N/A N=58 Sleep and Emotional Memory in Peripubertal Anxiety
Anxiety
Primary: Scores on the Lure Generalization Index (a Behavioral Measure of Generalization) — .24; .26; .14; .10 units on a scale — p=<.046
N/A N=37 A Unified Treatment for Anxiety Disorders
Emotional Disorders · Anxiety Disorders
Primary: Anxiety Disorders Interview Schedule for DSM-IV — 5.23; 5.09; 3.18; 5.14 score on a scale
N/A N=94 Approach-Avoidance Conflict-a Multi-level Predictor for Therapy Response
Generalized Anxiety Disorder
Primary: For Aim1: Baseline Generalized Anxiety Disorder Symptoms as Measured by the Generalized Anxiety Disorder - 7 Item Scale (GAD-7). — 12.85; 11.62 units on a scale — p=.088
N/A N=81 Memory and Fear Study (Fear of Memory Loss Study)
Anxiety and Fear
Primary: Fear and Avoidance of Memory Loss (FAM) Scale Score at Follow-up — 63.9; 60.3 score on a scale
N/A N=27 Strategies for Treating Anxiety Research Study
Anxiety Disorders · Anxiety
Primary: Number of Patient Participants Retained in the Intervention (Out of All of Those Enrolled), as Measured by Completion to All Study Treatment Visits. — 17 Participants
N/A N=128 Exercise and Pharmacotherapy for Anxiety in Cardiac Patients
Anxiety · Cardiovascular Disease
Primary: Change in Hospital Anxiety and Depression Scale (HADS), Anxiety — -3.9; -5.7; -3.5 score on a scale — p=0.038
N/A N=40 Relaxation Treatment for Anxiety in Adults Aged 60 or Older
Anxiety Disorders
Primary: Change in Anxiety Symptoms — 17.95; 26.2 score on a scale
N/A N=99 Fear, Gastrointestinal Distress, and Interoception: Physiological and Psychological Mechanisms in Eating Disorders
Feeding and Eating Disorders
Primary: Subjective Rating of Fear — -36.9444; -23.9219; -47.3611; 85.6250 units on scale*minutes — p=.879
N/A N=21 Neurally Targeted Cognitive Training to Augment CBT Outcomes in Pediatric Anxiety
Anxiety Disorders
Primary: Change in Brain Activation and Connectivity in the Task-control Network (TCN) — 0.020; -0.206; 0.305; -0.004 Arbitrary Units
N/A N=40 Family-Based Prevention Program for Childhood Anxiety
Anxiety Disorders
Primary: Number of Children With Child Anxiety Diagnosis — 20; 20 participants
N/A N=136 Effectiveness of a Family-Based Treatment for Preventing Anxiety Disorders in At-Risk Children
Anxiety Disorders
Primary: Anxiety Disorders Interview Schedule for Diagnostic and Statistical Manual for Psychological Disorders-IV, Child and Parent Versions (C/P-ADIS) — 19; 3 participants with…
Phase 4 N=89 Stress Reduction Techniques and Anxiety: Therapeutic and Neuroendocrine Effects
Generalized Anxiety Disorder
Primary: Active Symptoms of Generalized Anxiety Disorder — 13.65; 16.27 units on a scale
N/A N=56 The Effects of Emotional Exposure on State Anxiety
Generalized Anxiety Disorder
Primary: STAI-Y1 Score Assessed at Baseline, Post-Condition and Post-Exposure — 33.48; 33.53; 27.43; 29.78 score on a scale — p=>.05
N/A N=214 Brain Response Associated With Parent-based Treatment for Childhood Anxiety Disorders
Anxiety Disorder of Childhood · Separation Anxiety Disorder of Childhood · Social Anxiety Disorder of Childhood
Primary: Change From Baseline Anxiety Severity on the Pediatric Anxiety Rating Scale (PARS) at Week 12. — -11.82; -6.29; -8.47; -6.54 score on a scale
N/A N=305 Kids FACE FEARS Comparative Effectiveness Research
Child Anxiety · Anxiety Disorders · Anxiety
Primary: Promis Pediatric Short Form v. 2.0-Anxiety (Parent Proxy/Caregiver Report) — 65.7; 66.0; 59.2; 59.1 T-Score
N/A N=75 Assessing Mechanisms of Anxiety Reduction in Animal-assisted Interventions
Social Anxiety Disorder · Social Anxiety · Social Anxiety Disorder of Childhood
Primary: Self-reported Affective Experience — 10.19; 10.00; 10.28; 8.33 units on a scale — p=.723