N/A N=40 Sleep Apnoea Breathing Record Exploratory Study (SABRES)
Sleep Apnea
Primary: Correlation Between the Trial Device and an Established Device — 0.955 correlation coefficient
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=89 Sleep Disordered Breathing, Obesity and Pregnancy Study (SOAP)
Obese · Pregnancy · Sleep Disordered Breathing
Primary: Uterine Artery Doppler Mean Pulsatility Index -by Ultrasound — 1.0; 1.0; 1.0; 1.0 Mean PI
N/A N=169 Sleep Apnea Intervention for Cardiovascular Disease Reduction
Obstructive Sleep Apnea
Primary: Change From Baseline in 24-hour Blood Pressure at Months 6 and 12 by Pooled Arms — 1.82; 1.06; 0.59; -0.73 mmHg
Phase 3 N=1,105 Apnea Positive Pressure Long-Term Efficacy Study
Lung Diseases · Sleep Apnea Syndromes · Sleep
Primary: Effect of CPAP on Neurocognitive Function: E/F Function- SWMT-OMD — 0.035; -0.074; 0.072; 0.018 score on a scale — p=0.0074
N/A N=34 Positive Airway Pressure Program
Sleep Apnea, Obstructive
Primary: Participant Providing Feedback — 26 Participants
N/A N=22 Combination Therapy to Treat Sleep Apnea
Sleep Apnea, Obstructive
Primary: Model Prediction of Absence/Presence of OSA: Ventilation That Causes an Arousal From Sleep (Varousal) — 5.7; 5.2 L/min — p=0.05
N/A N=108 Obstructive Sleep Apnea in Pregnancy
Sleep Apnea, Obstructive · Pregnancy · Obesity, Morbid
Primary: Number of Participants With a Negative Obstructive Sleep Apnea (OSA) Home Sleep Test Result — 61 Participants
N/A N=100 Oxygen Saturation Patterns in Post-Op Patients at Risk for Obstructive Sleep Apnea
Obstructive Sleep Apnea
Primary: Presence of Repetitive Reductions in Nasal Airflow Patterns in the Pulse Oximetry Saturation Trend Data. — 30 participants
N/A N=144 Evaluating the Relationship Between Sleep-Disordered Breathing and Daytime Alertness
Sleep Apnea, Obstructive
Primary: Subjective Sleepiness — 11.8; 10.2; 9.9 units on a scale
N/A N=4,577 Incidence of Obstructive Sleep Apnea in Pregnancy
Obstructive Sleep Apnea · Pregnancy
Primary: Positive Berlin Questionnaire Indicative of Sleep Disordered Breathing — 1343; 96 participants — p=0.001
Phase 4 N=14 Sleep and Breathing in the General Population - Chemical Stimuli
Sleep-disordered Breathing
Primary: The Central Apnea-hypopnea Index — 14.1; 29.9 events per hour
Phase 2 N=36 Apnea and Insomnia Relief Study
Sleep Apnea Syndromes · Insomnia Disorder · Stress Disorders, Post-Traumatic
Primary: World Health Organization Quality of Life (WHOQOL-BREF) — 11.26; 9.75; 12.78; 10.84 units on a scale
Early Phase 1 N=63 Respiratory and Autonomic Plasticity Following Intermittent Hypoxia
Sleep Apnea Syndromes
Primary: Ventilation (Aim 1) — 1.19; 1.14; 1.35; 1.16 fraction of baseline — p=0.001
N/A N=70 Mechanisms of Endothelial Cell Dysfunction in Sleep Apnea
Obstructive Sleep Apnea · Hypoxemia
Primary: ODI — 24.71; .97 events/hour
N/A N=25 Atrial Fibrillation Recurrence in Sleep Apnea
Sleep Apnea · Atrial Fibrillation
Primary: Number of Subjects Who Had Atrial Fibrillation Recurrence at 1 Year — 3; 3 participants
N/A N=47 Estimating Apnea Phenotypes From Polysomnography: Oxygen
Sleep Apnea
Primary: Apnea-hypopnea Index — 40.5; 57.9; 48.5; 74.3 events/hour — p=0.4
N/A N=45 Understanding the Sleep Apnea/Insomnia Interaction
Sleep Apnea Syndromes · Sleep Initiation and Maintenance Disorders
Primary: Insomnia Severity Index Score — -8.2; -7.33; -6.27 score on a scale — p=0.8
N/A N=29 Bipap Automatic Servo Ventilation (autoSV) Advanced in Central Apnea Patients
Cheyne-Stokes Respiration · Sleep Apnea, Central
Primary: Apnea/Hypopnea Index (AHI) — 55; 37; 12 Apnea-Hypopnea events per hour
N/A N=15 The Effects of Trazodone on Sleep Apnea Severity
Sleep Apnea, Obstructive
Primary: Apnea-Hypopnea Index — 38.7; 28.5 events/hour
N/A N=317 Obstructive Sleep Apnea in World Trade Center Responders
Obstructive Sleep Apnea
Primary: Adherence to CPAP Pre-crossover — 1; 0.89 Hours/night
N/A N=25 The Role of Oxidative Stress in the Cardiovascular Consequences of Sleep Apnea
Sleep Apnea
Primary: Flow Mediated Dilation — 5.7; 9.5; 7.3 percentage change of vessel diamter — p=0.02
N/A N=146 Reducing Heart Failure Re-admissions by Enhancing Sleep Apnea Treatment Adherence
Congestive Heart Failure · Sleep Apnea Syndromes
Primary: Number of Participants Adhering to Positive Airway Pressure (PAP) — 5; 3 Participants — p=0.72
Phase 4 N=74 Oxygen Versus PAP for Sleep Apnea in Heart Failure
Heart Failure · Sleep Apnea Syndromes
Primary: Left Ventricular Ejection Fraction — 1.63; 1.69; 4.42 percent of LV diastolic volume
Phase 2 N=49 Apnea, Bariatric Surgery Versus Continuous Positive Airway Pressure (CPAP) Trial
Obstructive Sleep Apnea · Obesity
Primary: Effective Apnea Hypopnea Index — 29.5; 20.0 Events per hour
N/A N=32 Auto Continuous Positive Airway Pressure (CPAP) Based Energy Spectrum Analysis of Flow for Treatment of Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS)
Sleep Apnea, Obstructive
Primary: Apnea Hypopnea Index (AHI) — 2.4 events per hour
Phase 3 N=240 Effect of Self-Management on Improving Sleep Apnea Outcomes
Sleep Apnea Syndromes
Primary: CPAP Adherence — 2.8; 3.9 hours per night — p=0.001
Phase 3 N=225 Diagnosis and Treatment of Sleep Apnea in Cerebrovascular Disease
Obstructive Sleep Apnea · Stroke · Transient Ischemic Attack
Primary: Sleep Apnea Diagnosis Rate — 58; 5 participants
N/A N=9 Long QT Syndrome and Sleep Apnea
Long QT Syndrome · Sleep Apnea
Primary: QT Interval (Corrected) Baseline Visit — 453.4 square root of seconds — p=0.73
N/A N=8 Apnea Hypopnea Index Severity Versus Head Position During Sleep
Sleep Disordered Breathing · Sleep Hypopnea · Sleep Apnea
Primary: Number of Participants With Apnea Hypopnea Index (AHI) Severity Improvement — 8 Participants — p=<.05
Phase 2 N=13 DAW1033B2 in Obstructive Sleep Apnea
Obstructive Sleep Apnea (OSA)
Primary: Apnea Hypopnea Index (AHI, Events/Hour of Sleep) — 33; 20.4 events/hour of sleep — p=0.47