N/A N=248 Aspiration in Acute Respiratory Failure Survivors
Dysphagia
Primary: Percentage of Participants Experiencing Aspiration — 70; 52 percentage of participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=513 Oral Suction Intervention to Reduce Aspiration and Ventilator Events: NO-ASPIRATE
Respiratory Failure
Primary: Microaspiration as Measured by Tracheal Amylase — 13,086; 15,298 U/L — p=0.432
N/A N=25 AspiRATE: Novel Intervention to Acoustically Detect Silent Aspiration in Acquired Dysphagia.
Dysphagia, Oropharyngeal
Primary: Presence or Absence of Aspiration — 42 swallowing events with aspiration
N/A N=50 The Aspirometer: A Noninvasive Tool for Detecting Aspiration Aim 3
Deglutition Disorders
Primary: Numbers of Participants for Which the Aspirometer/HRCA Predicted the Passed Versus Failed Swallow Test Result — 4; 12 Participants
N/A N=146 Aspiration of Residual Gastric Contents
Infant, Premature · Nutrition, Enteral
Primary: Enteral Intake on Day of Life 7 — 27.5; 22.6 mL/kg per day — p=0.27
N/A N=154 Oropharyngeal Dysphagia in Patients With Community Acquired Pneumonia
Dysphagia · Pneumonia
Primary: Intra Hospital Mortality — 7; 0 Participants
Phase 2 N=400 LIPS-A: Lung Injury Prevention Study With Aspirin
Acute Respiratory Distress Syndrome
Primary: Number of Participants Who Developed Acute Respiratory Distress Syndrome (ARDS) Within 7 Days — 20; 17 participants — p=0.53
N/A N=117 Endotracheal Tubes for Prevention of Ventilator-associated Pneumonia
Ventilator-acquired Pneumonia
Primary: Percentage of Patients With Tracheal Bacterial Colonization — 8; 7; 9 percentage of tracheal colonization
Phase 3 N=725 Inhaled Amikacin Solution BAY41-6551 as Adjunctive Therapy in the Treatment of Gram-Negative Pneumonia
Pneumonia, Bacterial
Primary: Number of Participants Surviving Through LFU Visit — 191; 196; 64; 57 Participants — p=0.4263
Phase 2 N=1,068 Endotracheal Tubes to Prevent Ventilator-Associated Pneumonia
Ventilator-acquired Pneumonia
Primary: Quality of Life - 36-item Short-Form General Health Survey — 40.5; 40.0; 48.9; 45.9 score on a scale — p=0.78
N/A N=44,780 The INSPIRE-ASP PNA Trial
Pneumonia
Primary: Extended-Spectrum Days Of Antibacterial Therapy (ES-DOT) Per Empiric Day — 38690; 27971 Extended-Spectrum Days-of-Therapy
N/A N=171 Pivotal Aspiration Therapy With Adjusted Lifestyle Therapy Study
Obesity
Primary: Mean Percent Excess Weight Loss (%EWL) — 31.5; 9.8 Percent Excess Weight Loss
Phase 2 N=65 Novel Management of Airway Protection in Parkinson's Disease: A Clinical Trial
Parkinson's Disease · Dysphagia · Dystussia
Primary: Change in Voluntary Cough Peak Flow — 0.17; 0.51 l/s
N/A N=49 FOB in HSCT and Leukemia Patients With Acute Respiratory Symptoms and Pulmonary Infiltrates
Pulmonary Infiltrate New
Primary: Number of Patients With Positive Culture or Molecular Results After Brochoscopy — 40 participants
N/A N=530 Clinical Characteristics and Microbiology of Healthcare Associated Pneumonia
Healthcare Associated Pneumonia
Primary: Pathogens of Healthcare Associated Pneumonia, Measured by the Number of Participants — 15; 51; 195; 269 Participants
Phase 2 N=314 Strategies To Prevent Pneumonia 2 (SToPP2)
Infections, Hospital · Ventilator-Associated Pneumonia · Mechanical Ventilation Complication
Primary: Development of VAP (Clinical Pulmonary Infection Score) — 4.13; 4.45 units on a scale — p=0.1763
N/A N=83 Improving Oral Care to Reduce Hospital-Acquired Pneumonia (HAP) in the Acute Neurologically Impaired Adult
Pneumonia
Primary: Hospital Acquired Pneumonia Occurrences — 2; 13 participants
Phase 2 N=14 Cough and Swallow Rehab Following Stroke
Ischemic Stroke
Primary: Maximum Expiratory Pressure — 104.31 cm H2O (pressure measurement) — p=.001
N/A N=452 Study of Impact of Not Measuring Residual Gastric Volume on Nosocomial Pneumonia Rates
Ventilation-Associated Pneumonia
Primary: Compare Ventilator Associated Pneumonia Rates in Patients Receiving Early Enteral Feeding Without Residual Gastric Volume (RGV) Monitoring and in Patients With RGV…
N/A N=28 Prophylactic Bronchoscopy After Inhalation Injury in Burn Patients
Inhalation Injury · Pneumonitis · Pneumonia
Primary: All Cause Mortality — 0; 1 participants
Phase 2 N=143 Aerosolized Amikacin and Fosfomycin in Mechanically Ventilated Patients With Gram-negative Pneumonia
Pneumonia, Bacterial
Primary: Change From Baseline in Clinical Pulmonary Infection Score (CPIS) For Each Patient, Value Obtained From a Daily Assessment Over the 10 Day Study Period Was Compared to…
Phase 2 N=188 Effort to Prevent Nosocomial Pneumonia Caused by Pseudomonas Aeruginosa in Mechanically Ventilated Subjects
Pseudomonas Aeruginosa
Primary: Percentage of Participants With Nosocomial Pneumonia Caused by Pseudomonas Aeruginosa — 18.1; 12.5; 22.4 Percentage of participants — p=0.491
N/A N=37 Impact of Using Mini-Bronchoalveolar Lavage as a Diagnostic Test for Ventilator-Associated Pneumonia
Ventilator-Associated Pneumonia
Primary: Change in Antibiotic Usage or Exposure — 11.87; 7.76 days — p=0.26
N/A N=75 Urease Breath Test for Rapid Characterization of Pneumonia
Pneumonia, Bacterial
Primary: Adverse Events — 3; 0; 1; 0 Participants
Phase 2 N=158 Adjunctive Therapeutic Treatment With Human Monoclonal Antibody AR-105 (Aerucin®) in P. Aeruginosa Pneumonia
Pseudomonas Aeruginosa Pneumonia
Primary: Clinical Cure on Day 21 — 34; 37; 6; 5 Participants — p=0.6154
N/A N=414 Oral Hygiene in Assisted Living
Aging · Long-Term Care
Primary: Plaque Index Score for Long-Term Care (PI-LTC) - Baseline-Aim2 — 1.6; 1.6 score on a scale — p=0.77
Phase 2 N=175 Effect of Improved Oral Hygiene to Prevent Pneumonia in Hospitalized Patients
Pneumonia
Primary: Colonization of the Oral Cavity by Respiratory Pathogens (on Teeth/Denture/Buccal Mucosa) as Determined by Quantitative Cultures Expressed as Colony Forming Units (Cfu)…
Phase 3 N=834 A Trial to Reduce Pneumonia in Nursing Home Residents
Pneumonia · Lower Respiratory Tract Infection
Primary: Pneumonia — 119; 94 participants
N/A N=74 Antibiotic Efficacy in Pneumonitis Following Paraffin (Kerosene) Ingestion in Children
Kerosene Pneumonitis
Primary: Treatment Failure — 3; 2 participants — p=>0.50
N/A N=16 Assessing Ventilator Safety in Patients on Pressure-Support Ventilation
Acute Respiratory Failure · Mechanical Ventilation Complication · Ventilator-Induced Lung Injury
Primary: Respiratory System Driving Pressure Measure by Servo Ventilator (DPrs-servo) — 12.3 centimeters of water