Phase 2 N=20 Trial Of Double Umbilical Cord Blood Transplantation
Hematological Malignancies
Primary: Percentage of Participants Alive at 1 Year After Transplant — 40 percentage of participants
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Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=30 Cerebral Blood Flow During Propofol Anaesthesia
Gastrointestinal Neoplasms
Primary: Changes in Internal Carotid Artery Blood Flow by Treatment of Anaesthesia-induced Hypotension — 27 ml/min — p=0.0276
Phase 2 N=17 Adverse Effects of RBC Transfusions: A Unifying Hypothesis
Healthy Volunteers
Primary: The Effects of Storage-related RBC Changes on Acetylcholine-stimulated (NO-mediated) Forearm Blood Flow. — 19.02; 18.42; 17.61; 22.89 mL / 100 mL / min
N/A N=542 Helping Hypertension Patients to Interpret Blood Pressure Readings and Motivate Blood Pressure Control
Hypertension
Primary: Number of Participants Who Measured Blood Pressure as Instructed (Assessed on Questionnaire) — 34; 47; 50 Participants — p==0.05
Phase 1 N=12 Impact of Steady State Cobicistat and Darunavir/Cobicistat on the Pharmacokinetics and Pharmacodynamics of Oral Anticoagulants (Rivaroxaban, Apixaban) in Health Volunteers
Healthy Volunteers
Primary: Area Under the Concentration Versus Time Curve (AUC0-∞) for Rivaroxaban — 1049.19; 2274.3; 2226.38 hr*ng/ml
Phase 2 N=31 A Pilot Study of Alemtuzumab (Campath[R]) in Patients With Myelodysplastic Syndrome
Myelodysplastic Syndromes
Primary: Response to Treatment - Hematologic Improvement or Complete Response — 21 Participants
N/A N=29 Assessment of Blood Vessel Density in Kaposi's Sarcoma Lesions
Kaposi's Sarcoma
Primary: Preliminary Assessment of the Temperature of Kaposi's Sarcoma Lesions Compared to the Temperature in the Normal Skin Measured With Thermography — 1.1 Celsius
Phase 2 N=18 Corticosteroids in Postoperative Critically Ill Neonates With Low Cardiac Output Syndrome With Congenital Heart Disease
Cardiac Output, Low
Primary: Blood Pressure. — 6; 5.89 mmHg
N/A N=106 Accuracy of Blood Loss Estimation After Vaginal Delivery
Postpartum Hemorrhage
Primary: Difference in Actual Blood Volume and Estimated Blood Volume in Milliliters. — -20.8; -41.7; -53.5; -96.0 milliliters — p=<0.05
Phase 2 N=29 Alemtuzumab (Campath) to Treat T-Large Granular Lymphocyte Leukemia
T-LGL Lymphoproliferative Disorders
Primary: Number of Participants With Hematological Response After Three Months of Alemtuzumab — 15 Participants
Phase 4 N=44 The Effect of Nebivolol on Endothelial Dysfunction in African Americans With Hypertension
High Blood Pressure
Primary: Endothelial Function Measured by Forearm Blood Flow (FBF) at 12 Weeks — 2.739; 2.679; 1.963; 2.221 mL/100 mL/min
Phase 2 N=40 Preventing Stem Cell Transplant Complications With a Blood Separator Machine
MDS (Myelodysplastic Syndrome) · Myeloproliferative Disorder · Lymphoma, Non-Hodgkin
Primary: Overall Survival — 36 Participants
Phase 3 N=87 The Use of Tranexamic Acid to Reduce Blood Loss in Acetabular Surgery
Acetabular Fractures
Primary: Allogenic Blood Transfusion Rates — 21; 13 Participants
Phase 3 N=6 A Study of BAX 930 in Children, Teenagers, and Adults Born With Thrombotic Thrombocytopenic Purpura (TTP)
Thrombotic Thrombocytopenic Purpura (TTP)
Primary: Number of Participants With Acute Thrombotic Thrombocytopenic Purpura (TTP) Events During Prophylactic Treatment — 0; 0; 1 Participants
N/A N=1,051 Shock, Whole Blood, and Assessment of TBI S.W.A.T. (LITES TO 2)
Hemorrhagic Shock · Traumatic Brain Injury
Primary: 4 Hour Mortality — 50; 32 Participants