N/A N=6 Temporary Anchorage Devices for Ridge Preservation
Ridge Preservation
Primary: Changes in Width of Extraction Site (Ridge) — 0.7; 1.3 mm — p=<0.05
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=22 Bone Augmentation Techniques in Extraction Sockets
Tooth Loss
Primary: Changes in Hard Tissue Composition — 35.82; 31.76 mm
N/A N=9 Bioactive Glass (Sol-gel) for Alveolar Bone Regeneration After Surgical Extraction
Bone Loss · Vertical Alveolar Bone Loss · Horizontal Alveolar Bone Loss
Primary: Change in Alveolar Crestal Bone Height — 0.32; 0.84; 1.59; 0.96 mm
Phase 4 N=43 Alterations of GCF Levels of Sclerostin and DKK-1 in Postmenopausal Osteoporosis
Osteoporosis, Postmenopausal · Periodontitis
Primary: Sost Values for 6th Month — 1389.177; 1085.405; 1596.585; 2131.87 ng/ml — p=<0.01
N/A N=46 Effect of Healing Time on New Bone Formation Following Tooth Extraction and Ridge Preservation With Demineralized Freeze-Dried Bone Allograft
Bone Augmentation
Primary: Percent New Vital Bone Formation — 32.63; 47.41 percentage of vital bone
N/A N=37 The Influence of Bone Allograft Particle Sizes on the Quantity and Quality of New Bone Formation in Grafted Extraction Sockets and Edentulous Ridges
Alveolar Ridge Augmentation · Alveolar Ridge Preservation
Primary: New Bone Formation (in %) With the Use of Small vs. Large Particle Bone Allografts — 17.3; 25.9; 41.0; 31.4 % of new bone
N/A N=43 Ridge Preservation Following Tooth Extraction Using Two Mineralized Cancellous Bone Allografts
Alveolar Bone Loss
Primary: % Vital Bone Formation (Histological) — 27.19; 24.08 percentage
N/A N=66 Histological Evaluation of Healing Following Ridge Preservation Using a Combined Cortical/Cancellous Mineralized Freeze-Dried Bone Allograft
Alveolar Bone Loss
Primary: % Vital Bone Formation (Histological) — 26.4; 24.5; 28.8 percentage of total area
N/A N=32 Risk Factors for Implant Bone Loss in Patients With Diabetes Mellitus
Diabetes
Primary: Radiographic Bone Level — 2.69; 2.54 mm
Phase 2 N=22 Bone Material Comparison in Maxillary Sinus Augmentation
Alveolar Bone Resorption · Sequela · Tooth Extrusion
Primary: Bone Density - Limited View CBCT (Cone-beam Computed Tomography) Measurements — 14.4; 1.5 percentage of bone height shrinkage
Phase 2 N=24 Treatment of Alveolar Bone Defects Using Aastrom Biosciences Autologous Tissue Repair Cell Therapy
Alveolar Bone Loss
Primary: Bone Regeneration — 79; 63 % bone height
N/A N=27 A Prospective Study: Alveolar Ridge Augmentation Using Tenting Screws, Acellular Dermal Matrix and Combination Particulate Grafts
Dental Alveolus · Oral Surgical Procedures, Preprosthetic
Primary: Gain in Horizontal Ridge Dimension — 3.33; 3.09 gain in ridge width (mm)
N/A N=180 Morphological Pattern of the Atrophic Posterior Maxillae
Bone Deficiency, Posterior Maxillae
Primary: Lateral Wall Thickness — 161 mm
N/A N=40 Ridge Preservation After Tooth Extraction Using Cortical Versus Cancellous Freeze Dried Bone Allograft
Tooth Extraction
Primary: Histologic Percentage of Vital Bone Formation — 12.98; 16.08 percentage of vital bone
Phase 3 N=77 Bone Loss in Women With Anorexia Nervosa
Anorexia Nervosa
Primary: Bone Mineral Density — 3.2; -0.6 percent change — p=<0.0001
Phase 3 N=26 Changes of Soft and Hard Tissues After Alveolar Ridge Preservation: Freeze-dried Bone Allograft vs. L-PRF Clot
Alveolar Bone Loss · Tooth Loss
Primary: Overall Horizontal Change in Alveolar Ridge Width — -1.34; -2.21 Millimeters
N/A N=41 An Assessment of Bone Augmentation in Post-Extraction Sockets
Unrestorable Dentition · Post-Extraction Sockets
Primary: Bone-fill in Grafted Post-extraction Sockets Versus Bone-fill in Non-grafted Post-extraction Sockets — 0.43; 0.27; 0.36; 0.28 mm
N/A N=44 Histological Comparison of Ridge Preservation Using Mineralized FDBA Alone Versus a Combined Mineralized-Demineralized Freeze Dried Bone Allograft
Tooth Extraction
Primary: Percent New Vital Bone Formation — 24.7; 36.2 percentage of vital bone
N/A N=41 Clinical and Radiographic Evaluation of Demineralized Freeze-Dried Bone Allograft Versus Platelet Rich Fibrin for the Treatment of Periodontal Intrabony Defects in Humans
Periodontitis
Primary: Change in Clinical Attachment Level (CAL) — 1.21; 1.03 mm
N/A N=44 Ridge Preservation Following Tooth Extraction Using Porcine and Bovine Xenograft Materials
Alveolar Bone Loss
Primary: % Vital Bone Formation (Histological) — 31.27; 36.21 % vital bone
N/A N=15 The Horizontal Ridge Augmentation Using Equine Xenograft and a Collagenated Porcine Cortical Lamina
Horizontal Ridge Deficiency
Primary: Change From Baseline in Radiological Bone Width Augmentation at 0 mm — 2.274 mm
N/A N=16 Clinical and Histological Evaluation of Deproteinizated Bovine Bone Allograft and Lyophilized Equine Bone Allograft for Sinus Lift.
Maxillary Sinus Floor Augmentation
Primary: Histomorphometric Evaluation of New Bone Formation. — 22.20; 22.84; 50.77; 46.20 percentage of millimeters
N/A N=5 Use of Mesenchymal Stem Cells for Alveolar Bone Tissue Engineering for Cleft Lip and Palate Patients
Cleft Lip and Palate
Primary: Amount of New Bone Mass Formed — 89 percentage of bone formation
Phase 2 N=63 Bone Loss and Immune Reconstitution in HIV/AIDS (BLIR-HIV)
HIV Infection · Bone Loss · Osteopenia
Primary: Baseline-Adjusted Means for C-terminal Telopeptide of Collagen (CTx) Levels — 0.092; 0.297; 0.122; 0.331 ng/ml
N/A N=10 A Feasibility Study for Growth Bone Vertically With Titanium Mesh and Allograft in Lower Posterior Jaw
Alveolar Bone Loss
Primary: Bone Height — 12.2 millimeters
N/A N=102 Wound Healing Following Tooth Extraction and Ridge Preservation Using DFDBA Alone in Particulate Fiber Form and in Combination With Xenograft
Dental Extraction · Wound Heal
Primary: Percentage Vital Bone Formation — 37.33; 40.76; 24.46; 23.85 percentage of vital bone formation
N/A N=59 Efficacy of Socket Grafting for Alveolar Ridge Preservation
Atrophy of Edentulous Alveolar Ridge
Primary: Alveolar Ridge Volumetric Changes — -8.36; -15.83 percentage of volume change
N/A N=24 Ridge Preservation Comparing an Intrasocket Graft Alone to an Intrasocket Graft Plus a Facial Overlay Graft
Clinical Efficacy
Primary: Horizontal Ridge Dimension — -1.6; -0.3 mm
Phase 4 N=53 Alendronate Prevents Microarchitectural Deterioration of Trabecular Bone in Early Postmenopausal Women
Osteopenia · Osteoporosis
Primary: Mean % Change From Baseline in Trabecular Number (Tb.N) by HR-pQCT — 2.1; -0.6; 0.9; 4.1 Percent change
N/A N=30 Influence of Mucosa Tissue Thickness on Marginal Bone Loss of Implants With Smooth Collars
Gingival Tissue
Primary: Radiographic Peri-implant Bone Change (Measured in Millimeters) Between Baseline and 12 Months Follow-up. — 0.78; 0.61 millimeters