N/A N=1,516 Brain Injury Rehabilitation Improving the Transition Experience
Traumatic Brain Injury
Primary: Participation Assessment With Recombined Tools - Objective 17 (PART-O-17) — 1.30; 1.33 units on a scale — p=0.44
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=35 Neural Bases of Cognitive Rehabilitation for Brain Injury
Brain Injury
Primary: Change From Baseline on a Composite Measure (Z-score) of Attention, Working Memory, and Executive Functions — 0.26; .01 Change to Z (composite) score
N/A N=6 Deep Brain Stimulation for the Treatment of Traumatic Brain Injury
TBI (Traumatic Brain Injury)
Primary: Percent Change in Trail Making Test Part B Time to Completion — -25.6 percent change in time
N/A N=49 Training in Goal-directed Attention Regulation for Individuals With Brain Injury
Brain Injury
Primary: Self-report — 7.79; 6.49; 7.61; 7.73 units on a scale
N/A N=43 Association of Amino Acid Prevalence and Chronic Brain Injury
Chronic Traumatic Brain Injury
Primary: Change From Baseline of Concentrations of Essential Amino Acid at 1.5 Hours After Eating — 487.28; 553.70; 1224.19; 1339.54 µM
N/A N=55 Cognitive-Behavioral Therapy for Veterans With TBI
Insomnia · Traumatic Brain Injury
Primary: Change in Insomnia Severity — 8.833; 7.810; 9.625; 8.364 score on a scale
N/A N=91 Executive Functioning in TBI From Rehabilitation to Social Reintegration: COMPASS
Traumatic Brain Injury · Post-Traumatic Stress Disorder
Primary: Change From Baseline in Community Reintegration for Injured Service Members at 2 Months — 40.22; 37.79 score on a scale
N/A N=120 Neurocognitive Evaluation of Mild Traumatic Brain Injury in the Hospitalized Pediatric Population
Mild Traumatic Brain Injury · Concussion
Primary: The Feasibility of Inpatient Bedside Neurocognitive Testing of Pediatric Patients With Minor Traumatic Brain Injury. — 120 participants
Phase 2 N=122 Brain Tissue Oxygen Monitoring in Traumatic Brain Injury (TBI)
Severe Traumatic Brain Injury
Primary: Fraction of Time That Brain Oxygen Levels Are Below the Critical Threshold of 20 mm Hg . — 0.15; 0.44 Proportion
N/A N=184 Intervention to Promote Survivor Resilience and Adjustment: Efficacy and Sustainability
Traumatic Brain Injury
Primary: Number of Subjects Completing the Two Structured Outpatient Intervention Programs Resilience and Adjustment Intervention (RAI) vs. RAI With Follow-up Booster Sessions…
Phase 2 N=50 Treatment of Traumatic Brain Injury With Hyperbaric Oxygen Therapy
Brain Injury, Chronic
Primary: Computer Cognitive Test Scores - ImPACT Verbal Memory — 70.48; 74.21; 78.12; 75.36 units on a scale
Phase 1 N=52 Behavioral and Neuroimaging Changes After Cognitive Rehab in Traumatic Brain Injuries (TBI) and Mild Cognitive Impairment (MCI)
Mild Cognitive Impairment · Alzheimer's Disease · Traumatic Brain Injury
Primary: Memory Test Accuracy on Trained Stimuli — 53.9; 37.6; 48.9; 37.3 Percent correct
N/A N=18 Brain Markers of Improvements in Cognitive Functioning
TBI (Traumatic Brain Injury) · Brain Injuries · Stress
Primary: Composite Score of Attention and Executive Functioning From a Neurocognitive Test Battery — 0.18; -0.06 units on a scale
N/A N=23 Optimizing Cognitive, Environmental, and Neuromotor Stimulation in Traumatic Brain Injury
Traumatic Brain Injury · Dementia Alzheimers · Military Activity
Primary: Change in Executive Functioning as Assessed by the Trail Making Test — -9.2; 24.7 change in seconds — p=.323
N/A N=39 One-Day Life Skills Workshop for Veterans With TBI, Pain and Psychopathology
Mild Traumatic Brain Injury · Distress-based Psychopathology · Chronic Pain
Primary: World Health Organization-Quality of Life (WHO-QOL) — 6.11; 5.20 units on a scale
N/A N=165 Acute Neurobehavioral Program for Improving Functional Status After TBI
Traumatic Brain Injury
Primary: Functional Independence Measure Scores — 88.11; 89.79; 120.57; 119.67 units on a scale
N/A N=32 Effects of Bright Light Therapy in Mild Traumatic Brain Injury
Concussion, Mild · Post-Concussion Symptoms · Sleep Problems
Primary: Performance on Multiple Sleep Latency Test (MSLT) — 6.67; 7.32; 6.73; 7.88 minutes
N/A N=40 Transcranial Direct Current Stimulation for the Treatment of Deficits After Traumatic Brain Injury
Traumatic Brain Injury · Post Concussive Symptoms · Depression
Primary: Examiner Score — 0.617; 0.907; 0.865; 1.155 score on a scale
N/A N=6 Team Based Initiative Support
Traumatic Brain Injury
Primary: Number of Participants Who Reported 5 Themes — 6; 6; 6; 6 participants
Phase 2 N=61 A Study of Modified Stem Cells in Traumatic Brain Injury (TBI)
Traumatic Brain Injury
Primary: Change From Baseline in Fugl-Meyer Motor Scale (FMMS) Score at Week 24 Among All Patients — 6.0; 11.0; 8.1; 2.3 Change in score on a scale from baseline — p=0.0401
N/A N=37 Wellness Programs for Brain-Injured Individuals
Depression · Anxiety · Stroke
Primary: Depression Score Change on Geriatric Depression Scale — -.29; -1.46 units on a scale
N/A N=108 Brain Training to Enhance Frontal Lobe Reasoning
Traumatic Brain Injury
Primary: Glasgow Outcome Scale-Extended — 6.21; 6.30 units on a scale
N/A N=33 rTMS to Improve Cognitive Function in TBI
Traumatic Brain Injury
Primary: Trail Making Test Part B — 52.1; 45.3; 52.9; 50.8 T-score
Phase 2 N=19 CDP-Choline and Working Memory After TBI: A Neuroimaging Study
Brain Injuries
Primary: Cognitive Composite Score for Group of Subjects With TBI and Healthy Controls Matched by Age, Education, and Treatment Group. — 42.750; 50.500; 49.500; 55.000 T-score…
N/A N=110 Mindfulness-Based Stress Reduction to Improve Neuropsychological Functioning in Acquired Brain Injury
Stroke
Primary: State-Trait Anxiety Inventory — 32.8; 32.5 Score on a scale — p=.694
N/A N=176 One-day Life Skills Workshop for Veterans With TBI, Pain, and Psychopathology: Evaluating Efficacy and Mechanism of Change
Traumatic Brain Injury · Chronic Pain · Post Traumatic Stress Disorder
Primary: The Depression Anxiety and Stress Scale (DASS-21) -TOTAL Score — 28.97; 30.77 units on a scale
N/A N=68 Light Therapy for Moderate Traumatic Brain Injury
Moderate Traumatic Brain Injury (TBI)
Primary: Safety and Feasibility of Applying Light Therapy After Moderate TBI — 24; 19 Participants
Early Phase 1 N=35 Remediation of Impaired Self-Regulation in Patients With Mild TBI
Mild Traumatic Brain Injury
Primary: Blood Oxygen Level Dependent (BOLD) Brain Signal Measured Using Functional MRI. — 270; 111 voxels — p=<0.0001
N/A N=12 Acute Intermittent Hypoxia in Traumatic Brain Injury
Brain Injuries, Traumatic
Primary: Change in Vitals at Visit 2 — 0 Participants
Phase 4 N=26 Methylphenidate for Attention Problems After Pediatric TBI
Traumatic Brain Injury · TBI · ADHD
Primary: Parent Outcome-Vanderbilt ADHD Parent Rating Scales (VADPRS) — 1.10; 1.47; .84; 1.14 units on a scale