N/A N=100 Self-Control in Bulimia Nervosa
Bulimia Nervosa
Primary: Brain Activation Associated With P(Stop) — 0.02; 0.11; 0.04; 0.05 BOLD Signal
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=71 An fMRI Study of Self-regulation in Adolescents With Bulimia Nervosa
Eating Disorders
Primary: Magnetic Resonance Imaging Scans — 2.98; 2.96 mm — p=.03
Phase 2 N=10 Neurobiology of Bulimia Nervosa
Bulimia Nervosa
Primary: Change in Binge Eating Sum Score — -0.60; 0.89 score on a scale
N/A N=50 Cognitive Behavioral Therapy for Adolescent Binge Eating and Loss of Control Eating
Binge Eating · Eating Disorders in Adolescence · Overweight and Obesity
Primary: Binge (Loss-of-control) Eating Episode Frequency — 1.52; 6.05 episodes of behavior — p=.01
N/A N=5 An Open Label Trial of Memantine in the Treatment of Bulimia Nervosa and Body Dysmorphic Disorder
Bulimia Nervosa · Body Dysmorphic Disorder
Primary: Number of Binge Eating and Self-induced Vomiting Episodes — 20.67; 31.33; 21.67; 36.67 number of episodes
Phase 2 N=29 Effectiveness of Antibiotic Treatment for Reducing Binge Eating and Improving Digestive Function in Bulimia Nervosa
Bulimia Nervosa · Eating Disorders
Primary: Binge Frequency — 10.4; 11.3 Binge Episodes/Week — p=<.05
N/A N=32 App-Based Mindfulness Training for Individuals With Anorexia Nervosa and Bulimia Nervosa
Anorexia Nervosa · Bulimia Nervosa · Anorexia Nervosa, Atypical
Primary: Feasibility of Module Completion — 87.8 percentage of modules completed
Phase 4 N=88 Monoamine Contributions to Neurocircuitry in Eating Disorders
Eating Disorder
Primary: 5-HT Transporter Binding as Measured During the PET Scan — 1.68; 1.54; 1.46; 1.60 binding potential (BPND) — p=> 0.05
N/A N=99 Fear, Gastrointestinal Distress, and Interoception: Physiological and Psychological Mechanisms in Eating Disorders
Feeding and Eating Disorders
Primary: Subjective Rating of Fear — -36.9444; -23.9219; -47.3611; 85.6250 units on scale*minutes — p=.879
N/A N=22 Treatment of Binge Eating Disorder in Obesity: Naltrexone/ Bupropion Combination Versus Placebo
Binge Eating Disorder
Primary: Binge Eating Frequency (Continuous) — 4.4; 3.0 binge eating days (out of 28)
N/A N=152 Olanzapine Versus Placebo for Outpatients With Anorexia Nervosa
Anorexia Nervosa
Primary: Rate of Weight Change — 0.095; 0.260 kg/m^2 per month
Early Phase 1 N=13 Dopamine Receptor Contributions to Prediction Error and Reversal Learning in Anorexia Nervosa
Anorexia Nervosa
Primary: Measurement of Brain Activation (Measured in Percent Signal Change) During a Prediction Error Taste Reward Task Using Functional Magnetic Resonance Imaging (fMRI)…
Phase 3 N=89 Efficacy and Mechanisms of Naltrexone+Bupropion for Binge Eating Disorder
Binge-Eating Disorder
Primary: Change in Binge Eating Frequency — 6.4; 5.4 binge-eating episodes per month — p=.44
Phase 3 N=66 Behavioral and Pharmacologic Treatment of Binge Eating and Obesity: Maintenance Therapy
Binge-Eating Disorder · Obesity
Primary: Binge Eating Frequency (Continuous) — 0.86; 3.25 binge eating days per month — p=.07
Phase 4 N=93 Fluoxetine to Prevent Relapse and Enhance Psychological Recovery in Women With Anorexia Nervosa
Anorexia Nervosa · Eating Disorders
Primary: Proportion of Patients Remaining in Study at 1 Year — 0.265; 0.315 proportion of participants — p=0.57
N/A N=40 Neural Response to Food Stimuli: fMRI Changes Following Cognitive Behavioral Therapy for Binge Eating Disorder
Binge Eating Disorder · Overweight and Obesity
Primary: Blood Oxygen Level-dependent (BOLD) Functional Magnetic Resonance Imaging (fMRI) Response to Food-specific Stop-signal Task — -0.4; -0.3 percent signal change
Phase 4 N=104 Treatment of Binge Eating in Obese Patients in Primary Care
Obesity · Binge Eating
Primary: Binge Eating (Remission) — 10; 8; 6; 6 participants — p=0.60
Phase 3 N=3 Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Medication Change for Non-Responders
Binge-Eating Disorder · Obesity
Primary: Change in Binge-Eating Frequency — -14; -17.00 episodes per past 28 days
Phase 2 N=136 Multicenter Study to Evaluate the Efficacy and Safety of Oral ACT-539313 in the Treatment of Adults With Moderate to Severe Binge Eating Disorder
Binge-Eating Disorder
Primary: Change From Baseline to Week 12 in the Number of Binge Eating (BE) Days Per Week — -2.93; -2.93 BE days per week — p=0.9992
Phase 3 N=31 Behavioral and Pharmacologic Treatment of Binge Eating and Obesity: Specialist Treatment
Binge-Eating Disorder · Obesity
Primary: Binge Eating Frequency (Continuous) — 0.8; 12.1 Eating events/28 days — p=.0002
Phase 3 N=61 Craving, Binge Eating and Obesity
Binge Eating Disorder · Obesity
Primary: Frequency of Binge Eating Episodes — 0.8; 1.0 episodes/week
N/A N=159 Development of Eating Disorders Symptoms Among Children
Eating Disorders Symptoms
Primary: Number of Participants With >20 on the 26 Children Eating Attitudes Test — 26; 4 Participants
N/A N=177 Shifting Perspectives: Enhancing Outcomes in Anorexia Nervosa With CRT
Anorexia Nervosa
Primary: Change in Cognitive Flexibility - Condition 4 Trail Making Test of DKEFS — 11.89; 10.94; 11.47; 11.14 score on a scale — p=.507
N/A N=20 Binge Eating Syndrome Treatment for Older Women (BESTOW)
Binge Eating
Primary: Feasibility - Usage Rating Profile - Intervention — 5.44; 5.53 score on a scale
N/A N=31 FoodSteps for Binge Eating & Food Insecurity
Binge Eating · Type 2 Diabetes · Food Insecurity
Primary: Recruitment Rate — 30 Participants
Phase 4 N=41 A Double-blind, Placebo Controlled Trial of Risperidone for the Treatment of Anorexia Nervosa
Anorexia Nervosa
Primary: Change in Eating Disorder Inventory-2 Drive for Thinness Subscale (DT) — 1.36; 3.93 units on a scale
Phase 2 N=80 Vortioxetine for Binge Eating Disorder
Binge Eating Disorder
Primary: Change in Number of Binge Eating Episodes — .93; .76 binge eating episodes
N/A N=180 Efficacy Trial of a Dissonance Based Eating Disorder Program
Eating Disorder
Primary: Rosenberg Self-Esteem Scale (RSE). — 22.71; 22.50; 22.62 units on a scale
N/A N=102 Binge Eating Disorder Treatment Study
Binge Eating Disorder
Primary: Frequency of Binge Eating in the Past 28 Days — 16.06; 14.48; 6.26; 7.40 days
N/A N=90 Acceptance-based Group Intervention for Binge Eating
Binge-Eating Disorder
Primary: Change From Baseline in Binge Eating Scale (BES) at 4 Weeks, 3 Months and 6 Months — 17.38; 15.45; 10.52; 13.52 units on a scale