N/A N=26 Improving Care Coordination for Adolescents and Young Adults With Cancer
Cancer
Primary: Feasibility of Intervention Measure (FIM) AYA — 4.52 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=15 Self-Management of Cancer-Related Fatigue by Adolescents
Neoplasms · Fatigue
Primary: Change From Baseline in Fatigue Scale-Adolescent (FS-A) Score Categorized According to 1-5 Rating Scale of Resource Use and Resource Helpfulness. — -3; -3; -4; -4 units…
N/A N=73 Adolescents and Young Adults (AYAs) With Advanced Cancer
Adolescent and Young Adult Cancer Patient
Primary: Treatment Acceptability Questionnaire — 6.02 score on a scale
N/A N=195 The PRISM Intervention: a Multi-site Randomized Controlled Trial for Adolescents and Young Adults With Advanced Cancer
Cancer · Quality of Life · Anxiety
Primary: Pediatric Quality of Life Cancer Module — 66.89; 68.41 score on a scale
N/A N=27 Feasibility of Expressive Writing for Body Image Distress and Anxiety Among Adolescent and Young Adult Cancer Survivors
Adolescent Cancer · Young Adult Cancer · Body Image
Primary: Feasibility of In-home Body Image (BI) -Focused Expressive Writing (EW) Intervention for Post-treatment Adolescent and Young Adult (AYA) Cancer Survivors With BI…
N/A N=61 Symptom Management for YA Cancer Survivors
Cancer · Young Adult · Pain
Primary: Intervention Satisfaction: Satisfaction With Therapy and Therapist Scale-Revised (STTS-R) — 26.71; 27.33; 28.86; 27.75 scores on a scale — p=0.519
Phase 2 N=17 LSA4 Protocol for the Treatment of Advanced Pediatric and Adolescent Non-Hodgkins Lymphoma
Non-Hodgkin's Lymphoma
Primary: Complete Remission — 10 participants
N/A N=98 A Web-Based Physical Activity Intervention in Adolescent Survivors of Childhood Cancer
Cancer
Primary: Differences in Change in Daily Average of Moderate and Vigorous Physical Activity (MVPA) Levels Between Groups — -2.58; -2.12; -7.78 minutes — p=0.90
N/A N=60 Feasibility of a Self-Management + Peer Mentoring Intervention for Adolescent and Young Adult Childhood Cancer Survivors
Childhood Cancer Survivors
Primary: Feasibility Measure: Enrollment (Young Adult Survivors) - Number of Eligible Patients Consented and Completing Baseline — 50; 29 Participants
N/A N=14 Mindfulness-based Intervention for Teenagers With Cancer
Pediatric Cancer
Primary: Changes in Mood From Baseline to Post-intervention and 6 Months Post-intervention — 18.9; 17.8; 15.9; 12.8 units on a scale — p=0.613
Phase 2 N=120 Augmented Berlin-Frankfurt-Munster (BFM) Therapy for Adolescent/Young Adults With Acute Lymphoblastic Leukemia or Acute Lymphoblastic Lymphoma
Lymphoblastic Leukemia · Lymphoblastic Lymphoma
Primary: 3-Year Event-Free Survival (EFS) — 68 Participants
N/A N=126 Building Evidence for Effective Palliative/End of Life Care for Teens With Cancer
Cancer
Primary: Statement of Treatment Preferences (SOTP) a Tool to Measure Goals of Care. — 10; 22; 38; 19 Dyads — p=<0.05
N/A N=347 Communicating Health Information and Improving Coordination With Primary Care
Hypertension · Dyslipidemias · Diabetes
Primary: Undertreatment of Hypertension (>=140/90 mmHg), Dyslipidemia (LDL >=160 mg/dL or Triglyceride >=150 mg/dL), and/or Glucose Intolerance (if Prediabetes, Hemoglobin A1c…
Phase 3 N=78 Cisplatin-Based Chemotherapy and/or Surgery in Treating Young Patients With Adrenocortical Tumor
Stage I Adrenal Cortical Carcinoma AJCC v7 · Stage II Adrenal Cortical Carcinoma AJCC v7 · Stage III Adrenal Cortical Carcinoma AJCC v7
Primary: Five Year Event-free Survival (EFS) — 0.86; 0.53; 0.51 Estimated probability five year EFS — p=0.44
Phase 1 N=9 Lymphodepletion Plus Adoptive Cell Therapy With High Dose IL-2 in Adolescent and Young Adult Patients With Soft Tissue Sarcoma
Sarcoma
Primary: Number of Participants Who Experienced Serious Adverse Events and Adverse Events — 4; 5 Participants
N/A N=49 Mobile Health Fitness Program for Adolescent and Young Adult Childhood Cancer Survivors
Survivorship · Fatigue
Primary: Feasibility of the Technology-enhanced Fitness Program — 25; 24 Participants
N/A N=24 A Pilot Feasibility Trial of a Tailored Intervention to Improve Adherence in Adolescents and Young Adults With Cancer
Cancer · Adherence, Medication
Primary: Enrollment Rate — 70 Participants
N/A N=31 Peer Mentoring in Promoting Follow-up Care Self-Management in Younger Childhood Cancer Survivors
Cancer Survivor
Primary: Feasibility as Measured by Study Enrollment Rates, Retention Rates, Adherence to the Intervention, and Reasons for Study Drop Out. — 20; 11; 8; 0 Participants
N/A N=97 Decision Aid for Education and Support About Cancer Treatment
Cancer · Childhood Cancer
Primary: Acceptability of Decision Aid — 4.10; 4.06; 4.01; 4.13 Average Score on a Scale
Phase 1 N=21 Anti-CD19 White Blood Cells for Children and Young Adults With B Cell Leukemia or Lymphoma
ALL · B Cell Lymphoma · Leukemia
Primary: Number of Participants Who Received Preparative Chemotherapy Followed by Cluster of Differentiation (CD)19-Chimeric Antigen Receptor (CAR): CD19 CAR T-cells With < Grade…
N/A N=155 mHealth for Young Adult Cancer Survivors
Survivorship · Cancer · Psychological Well-Being
Primary: Retention — 74; 72 Participants
N/A N=32 Smart-phone Application to Promote Medication Adherence in Adolescents and Young Adults (AYA) With Cancer
Neoplasms
Primary: Feasibility and Acceptability of Using a Smart-phone Medication Reminder Application to Promote Adherence to Oral Medications by AYA With Cancer. — 21; 13 Participants
N/A N=10 Feasibility and Preliminary Efficacy of a Mindfulness-based Intervention for Children and Young Adults With High Grade or High-Risk Cancer and Their Caregivers
Glioblastomas · Sarcoma · Astrocytoma
Primary: Percentage of Eligible Dyads (Parent-child) Who Enroll During a Two-year Period — 100; 100 percentage of dyads
N/A N=89 Education Tools to Support Pediatric Survivor Care
Cancer · Pediatric Cancer
Primary: Survivor Care Knowledge Scale — 10.6; 11.2 score on a scale
Phase 3 N=588 Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma
Adult Alveolar Soft-part Sarcoma · Adult Angiosarcoma · Adult Epithelioid Sarcoma
Primary: Probability for Event Free Survival. — 0.8984; 0.7647; 0.6079; 0.4873 Probability of EFS at 5 years
Phase 2 N=64 Therapy for Children With Advanced Stage Neuroblastoma
Neuroblastoma
Primary: Overall Response Rate [Complete Response + Very Good Partial Response + Partial Response (CR + VGPR + PR)] — 42 Participants
N/A N=102 Videos for Advance Care Planning in Young Adults
Advanced Cancer
Primary: Increased Concordance Rate in Stated Goals of Care (Life-prolonging Medical Care, Selective Medical Care, or Comfort-focused Care) — 20; 15; 5; 10 Participants
Phase 2 N=72 Nutrition and Body Composition in Acute Lymphoblastic Leukemia
Precursor Cell Lymphoblastic Leukemia-Lymphoma · Vitamin D Deficiency
Primary: Change in Serum Vitamin D Level (Group A) — 5.5; -0.30; 1.0; 26.5 ng/ml
Phase 2 N=22 Pilot Study of Hyperthermic Peritoneal Perfusion (HIPEC) for Adolescent and Young Adults With Desmoplastic Small Round Cell Tumor
Advanced Cancers · Sarcoma
Primary: Recurrence Free Survival — 13.99 months
Phase 2 N=92 Radiation Therapy in Treating Young Patients With Gliomas
Brain Tumor · Central Nervous System Tumor
Primary: Marginal-failure Rate — 0 percentage of failure rate