N/A N=263 Does Capnography Prevent Hypoxemia During Endoscopic Retrograde Cholangiopancreatography and Endoscopic Ultrasound?
Hypoxemia
Primary: Number of Participants Experiencing Hypoxemia During Endoscopy — 57; 85 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=452 Use of Capnography in EGD and Colonoscopy With Moderate Sedation.
Hypoxia · Apnea · Hypotension
Primary: Number of Participants Experiencing Hypoxia During Capnography Monitoring. — 54; 59; 61; 63 Participants
N/A N=167 Using Capnography to Reduce Hypoxia During Pediatric Sedation
Hypoventilation · Hypoxia
Primary: Frequency of Staff Interventions for Hypoventilation. — 0.39; 0.396 Events per patient minute of sedation
N/A N=42 Capnography-Assisted Learned Monitored (CALM) Breathing Therapy for COPD
COPD
Primary: Mean Attendance Rate of CALM Breathing Treatment Sessions — 84.2 percentage of completed sessions
N/A N=47 Comparative Analysis of CO2 Monitoring Methods in Patients With CF Undergoing General Anesthesia
Cystic Fibrosis
Primary: Accuracy of CO2 Levels — 48.9; 39.5; 41.5; 44.3 mmHg
N/A N=49 Quantitative End Tidal CO2 Monitoring in the Delivery Room (DR)
Delivery Room Resuscitation
Primary: PCO2 Level Outside of Desired Range (40-60 mmHg) — 9; 8 participants
N/A N=29 A Comparison of Capnography Sampling Lines
Capnography
Primary: Capnography Measured CO2 Waveform Data as a Function of CO2 Cannula Sampling Filterline (CCSF) Stratified by Activity — 30.6; 0.0; 26.6; 0.2 mmHg
Phase 2 N=31 Capnometry-Assisted Breathing Training for COPD
Chronic Obstructive Pulmonary Disease
Primary: Number of Participants With Adherence to Home Breathing Exercises — 10; 5 Participants
N/A N=40 A Comparison of the Detection of Hypoventilation During Deep Sedation Utilizing Nasal End Title CO@ Versus Transcutaneous CO2 Measurement Techniques
Surgery · Hypoventilation
Primary: TcCo2 vs PACo2 Difference — 3.2 mmHG
N/A N=211 Detecting Post-Operative Respiratory Depression in Children
Respiratory Depression
Primary: Abnormal ETCO2 Values, Abnormal Pulse Oximetry Values, and Staff Interventions — 56; 58; 8; 15 participants
N/A N=32 Comparison of Non-invasive Respiratory Monitoring System (RMS) to Capnography for Respiratory Rate (RR)
Respiratory Monitoring
Primary: Respiratory Rate Accuracy Compared Between Experimental and Reference Devices — .63 Breath Per Minute
N/A N=200 Is End Tidal CO2 Level Elevation During Upper Endoscopy With CO2 Gas Insufflation Physiologically Significant
Endoscopy
Primary: Number of Procedures With Elevated End-tidal CO2 Levels — 8; 21 Procedures
N/A N=1,495 PRediction of Opioid-induced Respiratory Depression In Patients Monitored by capnoGraphY
Respiratory Depression
Primary: Determine Number of Subjects With RD While on Opioid Therapy — 655; 840 Participants
Phase 3 N=350 Breath Analysis Technique to Diagnose Pulmonary Embolism
Pulmonary Embolism
Primary: Phase I: Percentage Change in the Postoperative End Tidal CO2/O2 Ratio and D-dimer Concentration Relative to the Preoperative Measurement — 0; 136 percent change
N/A N=111 Nasal Continuous Positive Airway Pressure Versus Standard Care During Procedural Sedation for Gastrointestinal Endoscopy
Hypoxia · Endoscopy · Anesthesia Morbidity
Primary: Hypoxia Rate as Assessed by Number of Participants With at Least One Hypoxic Event — 3; 16 Participants
N/A N=27 INVSENSOR00032 and INVSENSOR00033 Respiration Rate Clinical Performance Study
Healthy
Primary: RRp Arms of Sensor Accuracy — 2.1 respiration per minute (RPM)
Phase 4 N=105 Pre-oxygenation With Real Time End-tidal Oxygen Measurements Versus Single Breath Measurements
Rapid Sequence Intubation
Primary: Real Time and Single Breath End-tidal (EtO2) Measurements — 34; 63; 92; 58.5 percentage of end-tidal oxygen
N/A N=77 Minimally Invasive Cardiac Output Monitoring Device
Cardiac Event
Primary: Establishment of a Dataset to Create an Algorithm to Measure Cardiac Output — 75; 2 Participants
N/A N=284 Evaluating the Non-Inferiority of Airmod to Capnostream™35
Respiratory Rate
Primary: Test of the Difference Between airRR and mancRR — 0.422; 14.362; 14.784 breaths per minute — p=<0.001
N/A N=40 Prophylactic nCPAP Following Bowel Surgery (Bio-REB File 11-27)
Postoperative Pulmonary Atelectasis · Surgery
Primary: Alveolar - Arterial Gradient — 70.6; 134 torr
N/A N=84 Endotracheal Tube Intracuff Pressure and Leak
Otolaryngological Surgery
Primary: Changes in the Intracuff Pressure — 3 cmH2O
Phase 2 N=54 Effectiveness of Continuous Negative External Pressure in Preventing Upper Airway Impairment During Routine Colonoscopy
Airway Obstruction · Apnea · Hypopnea
Primary: RI Events in the cNEP Group Compared to the no cNEP Group, Where RI is Defined as Either: i Oxygen Saturation < 90% or ii. Apneas/Hypopneas of > 15 Sec Duration i…
N/A N=90 Respiration Rate V2.0 in a Hospital Setting
Respiratory Rate
Primary: Mean Error (ME) +/- 1 Breath Per Minute, RR Sensor — -0.82 BrPM (breaths per minute)
N/A N=6 Rebreathing of Carbon Dioxide With a Device Used for Giving Inhalational Anaesthesia
Anesthetic Ventilatory Requirements
Primary: Airway Dead Space With Devices for Heat and Moisture Exchange of Respiratory Gas. — 136 mL
N/A N=76 Evaluating Air Leak Detection in Intubated Patients
Critical Care
Primary: CO2 Leakage Above the ETT Cuff, Measured Over Time. — 0.09; 0.22 [CO2 mmHg*hour]/hour
N/A N=21 Respiratory Rate Validation Study
Measure Accuracy of Respiratory Rate
Primary: Accuracy of Device Under Test for the Measurement of Respiratory Rate, Measured in Breath/Min — 2.9 breaths/min
N/A N=22 Improved Patient Recovery After Anesthesia With Hypercapnia Hyperpnoea
Hypercapnia
Primary: Recovery From Anesthesia — 53.0; 62.9 minutes — p=>0.05
N/A N=28 INVSENSOR00013 Respiratory Rate Clinical Performance Study
Healthy
Primary: RRp Arms of Sensor Accuracy — 1.2 respiration per minute (RPM)
N/A N=80 Assessment of the Capability of PulmoVista 500 to Continuously Monitor Changes of Ventilation Over Time
Mechanical Ventilation · Single-lung Ventilation · ARDS
Primary: Monitoring Capabilities of PulmoVista 500 — 0.9692; 0.9093 correlation coefficient
Phase 4 N=137 Safety Study of Analgesia After Craniotomy Surgery With End Tidal (ET) Carbon Dioxide (CO2) Monitoring
Pain
Primary: Respiratory Depression — 10.9; 10.5 breaths/minute