Phase 2 N=60 Metformin in Kidney Disease
Chronic Kidney Disease · Cardiovascular Disease · Metabolic Syndrome
Primary: Change is Leptin to Adiponectin Ratio (LAR) — 2.2; 1.3; 1.3; 1.4 ng/micrograms
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=36 Oral Contraceptives in the Metabolic Syndrome
Metabolic Syndrome X · Insulin Resistance · Obesity
Primary: Changes in Insulin Sensitivity Associated With Oral Contraceptive (OC) Use Compared Among (1) Obese Women and (2) Lean Women — 4.36; 6.62; 3.82; 8.23 mIU/L
Phase 2 N=200 Safety and Efficacy of Xenical in Children and Adolescents With Obesity-Related Diseases
Diabetes Mellitus · Hypertension · Metabolic Disease
Primary: Change in BMI Standard Deviation Score — -0.12; -0.06 Standard Deviation Score — p=0.007
Phase 4 N=204 Fixed Dose Intervention Trial of New England Enhancing Survival in SMI Patients
Serious Mental Illness · Schizophrenia · Schizoaffective Disorder
Primary: Number of Participants on Adequate Cardiovascular Prevention Care (Defined as Taking a Statin and Angiotensin Medication) — 66; 8 Participants
Phase 2 N=26 Exenatide in Extreme Pediatric Obesity
Obesity
Primary: Percent Change From Baseline in Body Mass Index at 3-months — -2.9; -0.15 percentage of change in BMI
N/A N=697 Enhancing Self Regulation as a Strategy for Obesity Prevention in Head Start Preschoolers
Obesity
Primary: Change in Body Mass Index Z-score — -0.01; 0.00; -0.04 Z-Score
N/A N=30 Estrogen Sensitivity and Ovulatory Dysfunction in Obesity
Obesity · Infertility
Primary: Luteinizing Hormone Pulse Amplitude — 2.73; 1.12 IU/L
Phase 2 N=45 Targeting Inflammation to Treat Cardiovascular Aging
Vascular Stiffness · Endothelial Dysfunction · Diastolic Dysfunction
Primary: Carotid-femoral Pulse Wave Velocity (CFPWV) — 831.3; 785.1; 538.0; 839.6 cm/sec
N/A N=226 The Resource Information Program for Parents on Lifestyle and Education
Pediatric Obesity
Primary: Feasibility (Parents' Interest in the SBIRT.) — 84.3; NA; NA; NA percentage of parents
N/A N=472 Family Obesity Intervention: Motivational Interviewing and Community Support
Obesity
Primary: Change in Adult Body Mass Index — 0.3; -0.1 kg/m2 — p=0.67
N/A N=145 The Effect of n-3 Polyunsaturated Fatty Acids in Patients With Psoriatic Arthritis
Psoriatic Arthritis
Primary: Change in Heart Rate Variability (HRV) Measure — 13.38; -13.48 ms
N/A N=511 DVD Lifestyle Intervention
Obesity
Primary: Body Weight — 99.8; 101.0 kilogram (kg) — p=0.001
N/A N=21 Investigation of a New Diet for the Treatment of Obesity in the NHS
Obesity
Primary: Body Weight Change — -12.99 kg — p=<0.0001
N/A N=76 Study of Brain, Reward, and Kids' Eating
Obesity, Childhood · Eating Behavior
Primary: Child Body Mass Index — 17.83; 18.78 kg/m-squred
N/A N=15 Growth Hormone Treatment on Phosphocreatine Recovery in Obesity
Obese · Growth Hormone Secretion Abnormality
Primary: Phosphocreatine Recovery — 0.74 correlation coefficient — p=0.02