Clinical Trial Search

Primary: Percentage of Participants With ≥50% Pain Reduction on the Numeric Rating Score (NRS) for Pain — 60; 72 percentage of participants — p=0.23

Primary: Avoidance of Neck Surgery — 24; 20; 3; 6 Participants

Primary: Visual Analogue Scale Score Referring to Radicular Pain (VAS-rad) — 58.7; 67.7; 13.6; 59.7 units on a scale

Primary: Change in Pain Numerical Rating Scale (Averaged Over Past 24 Hours) — -3.38; -2.30 score on a scale — p=0.057

Primary: Pain Scores (NRS) at 3-weeks — 6; 3 units on a scale — p=0.279

Primary: The Percentage of Participants With Reduction of 50% or More of Neck and Arm Pain NRS Score — 49.1; 68.5 percentage of participants

Primary: Change From Baseline to Week 4 in the Weekly Average of the Daily Pain Score as Derived From the Subject's Responses on the Pain Intensity Numerical Rating Scale…

Primary: Mean Change From Baseline (Day 1) to Week 4 in the Mean Numeric Pain Rating Scale (NPRS) Average Pain Score in the Affected Leg — -2.34; -1.16 Change in score on a scale…

Primary: Numerical Rating Leg Pain Score — 2.54; 3.56; 3.78 units on a scale

Primary: Percent of Peak Activation (%PA) — 51.72; 61.20; 88.1; 80.80 Percentage of Peak Activation (%PA)

Primary: Neck Disability Index — 17.9; 16.7 units on a scale from 0 to 100 — p=0.641

Primary: Visual Analog Scale — 5.638; 5.050; 5.094; 4.894 Centimeters

Primary: Composite Definition of Study Success — 65.3; 73.7; 37.4; 69.7 percentage of subjects analyzed — p=0.0021

Primary: Composite Clinical Success (CCS) Rate of the Simplify® Disc — 153; 105 Participants — p=0.017

Primary: Change in Strength in Both Groups After CESI. — 25; 30; 35; 30 Participants — p=.05

Primary: Average Leg Pain at 1 Month Measured Using the Numeric Pain Scale — 3.3; 3.7 units on a scale

Primary: Numeric Rating Scale (NRS) — 8.2; 8.2; 3.5; 3.2 units on a scale — p=<0.05

Primary: Number of Participants With Composite Clinical Success (CCS) of Simplify Disc — 68; 132 Participants — p=<.001

Primary: Recruitment Rate — 32 Participants

Primary: Pre-epidural Warm Sensation Quantitative Sensory Testing (QST) Results — 2.68; 5.67 Degrees Celsius — p=.04

Primary: Numerical Rating Scale (0-10), an Interval Pain Scale, on Which 0 Indicates no Pain and 10 Indicates the Worst Pain Imaginable — 7.1; 5.8 units on a scale

Primary: Number of Patients With Required Supplementation of Local Anesthetic by Surgeon — 13; 13 participants — p=1.0

Primary: Changes in QST Measures in Response to Acupuncture or Gabapentin at Visit 1, Visit 4 and Visit 7 for CS, WS, HP, CP (CS: Cold Sensation; WS: Warm Sensation; HP: Heat…

Primary: Injection Dispersal Patterns Measured (in cm) in the Superoinferior Directions on Post-injection MRI With a Calibrated Internal Measurement Software. — 14.73 cm

Primary: Pain Assessed by Visual Analogue Scale — 5.63; 5.92 units on a scale

Primary: Numeric Pain Rating Scale (NPRS) — 14; 3 Participants

Primary: Percentage of Participants Reporting ≥50% Reduction in Index Numeric Rating Scale (NRS) Arm Pain Score — 19; 23; 20; 20 Participants

Primary: Change in Opioid Analgesic Plasma Levels — 10.86; -11.4 ng/mL

Primary: Local Anesthetic Supplementation (Frequency) — 11; 7 participants — p=0.236

Primary: Occiflex Device Safety — 26 Number of adverse effects