N/A N=104 Interbody Fusion Devices in the Treatment of Cervicobrachial Syndrome
Radiating Pain · Myelopathy · Cervicobrachial Syndrome
Primary: Neck Disability Index — 17.9; 16.7 units on a scale from 0 to 100 — p=0.641
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=85 Evaluation of Fusion Rate of Anterior Cervical Discectomy and Fusion (ACDF) Using Cervios ChronOs™ and Bonion™
Intervertebral Disk Degeneration · Intervertebral Disk Displacement · Ossification of Posterior Longitudinal Ligament
Primary: Bone Fusion With CT(Postoperative 6 Months) — 26; 28 participants
N/A N=118 ViBone in Cervical and Lumbar Spine Fusion
Spondylosis · Cervical Spondylosis · Spondylolisthesis
Primary: Fusion Rates Per Level Using the Bridwell Interbody Grading Scale — 64; 50 Fusions
N/A N=710 INFUSE® Bone Graft/ PEEK Interbody Spacer/ Anterior Cervical Plate Pivotal Clinical Trial
Degenerative Disc Disease
Primary: Rate of Overall Success — 80.9; 59.9 percentage of participants — p=<0.001
N/A N=53 Lumbar Fusion With Nexxt Spine 3D-Printed Titanium Interbody Cages
Lumbar Degenerative Disc Disease · Lumbar Spinal Stenosis · Lumbar Spondylolisthesis
Primary: Interbody Radiographic Fusion Rate — 27; 10; 6; 24 Cages/Spinal Levels
Phase 3 N=231 Performance of the Hedrocel(R) Cervical Fusion Device
Symptomatic Cervical Disc Disease
Primary: Overall Clinical Success (NDI, Fusion, Additional Surgical Procedures) — 5; 33; 28; 2 participants
N/A N=352 Investigation of the Two Level Simplify® Cervical Artificial Disc
Cervical Degenerative Disc Disorder
Primary: Composite Clinical Success (CCS) Rate of the Simplify® Disc — 153; 105 Participants — p=0.017
N/A N=231 Outcome Study of Patients Treated With Translational Cervical Plate Used to Treat Degenerative Disc Disease
Degenerative Disc Disease
Primary: Radiographic Fusion — 66; 46; 37; 75 percentage of subjects
N/A N=29 OsteoStrux™ Collagen Ceramic Scaffold in Instrumented Lumbar Spine Fusion
Degenerative Changes · Stenosis · Spondylosis
Primary: Number of Posterolateral Gutters That Have Evidence of Arthrodesis (Fusion) at 3, 6, 12, and 24 Months, as Measured by X-rays. — 39; 34; 42; 36 Posterolateral Gutters
Phase 3 N=545 Study of Safety & Effectiveness of PRESTIGE® LP Cervical Disc vs. Anterior Cervical Fusion in Cervical DDD
Cervical Degenerative Disc Disease
Primary: Rate of Overall Success — 70.4; 63.2 percentage of participants — p=0.995
Phase 4 N=20 BIO4 Clinical Case Study: Cervical Spine
Degenerative Disc Disease · Trauma (Including Fractures) · Spondylolisthesis
Primary: Radiological Assessment : Fusion Status — 20 participants
N/A N=575 LDR Spine USA Mobi-C(R) Cervical Disc Prosthesis IDE
Degenerative Disc Disease
Primary: Composite Definition of Study Success — 65.3; 73.7; 37.4; 69.7 percentage of subjects analyzed — p=0.0021
Phase 4 N=65 Surgery Prevention by Transforaminal Injection of Epidural Steroids for Cervical Radicular Pain
Pain, Radiating
Primary: Avoidance of Neck Surgery — 24; 20; 3; 6 Participants
N/A N=267 Investigation of the Simplify® Cervical Artificial Disc
Cervical Degenerative Disc Disease
Primary: Number of Participants With Composite Clinical Success (CCS) of Simplify Disc — 68; 132 Participants — p=<.001
N/A N=81 Cellentra Viable Cell Bone Matrix (VCBM) Anterior Cervical Discectomy and Fusion Outcomes Study (VCBM/MaxAn)
Cervical Disc Degenerative Disorder
Primary: Change in NDI From Baseline — 52.1; 28.5; 24.0 score on a scale
N/A N=20 Clinical and Radiological Evaluation of Patients With DDD Following TLIF With 3-D Printed Titanium Cage
Intervertebral Disc Disease
Primary: Fusion Rate — 19; 1; 0 Participants
N/A N=184 Understanding Non-Response in Spine Fusion Surgery
Spine Fusion
Primary: Oswestry Disability Index — 41.3; 30.4; 19.4 score on a scale
N/A N=36 Accell Evo3™ Demineralized Bone Matrix in Instrumented Lumbar Spine Fusion
Degenerative Changes · Stenosis · Spondylosis
Primary: Time to Arthrodesis (Fusion) for Each Spinal Level (Unit), as Measured by X-rays. — 6 months to fusion
N/A N=17 Prospective Study of Thoracolumbar Spinal Fusion Graft
Lumbar Degenerative Disc Disease
Primary: Spinal Fusion Grade at 1 Year Via CT Scan — 1.67; 2.4 score on a scale
N/A N=89 SECURE®-C Cervical Artificial Disc Clinical Study/ SECURE-C Cervical Artificial Disc Postmarket Approval Study
Symptomatic Cervical Disc Disease
Primary: Individual Patient Overall Success — 127; 81; 67 participants
Phase 3 N=416 PCM Cervical Disc System
Radiculopathy · Myelopathy
Primary: Individual Patient Overall Success — 142; 98 participants
N/A N=5,050 Retrospective Evaluation of Performance of Coflex® Interlaminer Technology Versus Decompression With or Without Fusion
Spinal Stenosis
Primary: Overall Duration of Follow-up Care to Evaluate Overall Effectiveness of the Use of the Coflex® Interlaminer Technology — 201.26; 191.75 days
N/A N=500 Comparison of DISCOVER™ Artificial Cervical Disc and ACDF for Treatment of Cervical DDD (IDE Study)
Cervical Degenerative Disc Disease
Primary: Overall Success — 137; 110; 28; 13 participants who are successes
N/A N=178 Lumbar Degenerative Disc Disease Treated With Anterior Tension Band System (ATB) With ALIF/FRA Spacer
Lumbar Degenerative Disc Disease
Primary: Number of Subjects With Successful Radiographic Fusion — 90 Participants
N/A N=22 Assessment of nanOss Bioactive 3D in the Posterolateral Spine
Degenerative Disc Disease · Spinal Stenosis · Spondylolisthesis
Primary: Number of Patients With Fusion — 16 Participants
N/A N=69 Anterior Bridging Cage With Bone Substitute Versus Localized Autobone in Transforaminal Lumbar Interbody Arthrodesis
Stenosis · Fusion of Spine (Disease)
Primary: InCBB of Both Cages — 1.48; 1.43 score on a scale
Phase 4 N=36 Use of Forteo (Teriparatide) in Posterolateral Lumbar Spine Fusion
Lumbar Spondylosis · Lumbar Spondylolisthesis · Adult Degenerative Lumbar Scoliosis
Primary: Quality of Spine Fusion, Measured by the Number of Participants With Complete Spine Fusion at 1 Year — 11; 6 Participants
N/A N=30 Clavicle Splint for Pain Reduction After Posterior Cervicothoracic Surgery
Posterior Cervical Surgery · Posterior Cervical Fusion · Posterior Cervical Laminectomy
Primary: Average Neck Pain Level — 1; 1 units on a scale (VAS pain scale)
N/A N=19 Driving After Cervical Spine Surgery
Cervical Disc Disease
Primary: Change in Number of Total Collisions (TC) — 2 collisions/crashes
N/A N=128 Effect of Topical Corticosteroids on Dysphagia in Anterior Cervical Discectomy and Fusion
Cervical Disc Herniation · Cervical Degenerative Disc Disease · Cervical Spondylotic Myelopathy
Primary: Degree of Dysphagia Patients Experience (Burden) — 100; 100; 50; 75 score on a scale — p=0.394