N/A N=8 Postural Stability in Cervical Spinal Myelopathy
Cervical Spondylotic Myelopathy
Primary: Virtual Environment TBI System (VETS) Assessment of Static Posturography — 11; 13.0; 48.4; 19.1 Square Centimeters
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=575 LDR Spine USA Mobi-C(R) Cervical Disc Prosthesis IDE
Degenerative Disc Disease
Primary: Composite Definition of Study Success — 65.3; 73.7; 37.4; 69.7 percentage of subjects analyzed — p=0.0021
Phase 2 N=10 Tailored Computerized Mobilization of the Cervical Spine Utilizing the Occiflex Device for the Treatment of Chronic Neck Pain
Neck Pain
Primary: Occiflex Device Safety — 26 Number of adverse effects
Phase 3 N=416 PCM Cervical Disc System
Radiculopathy · Myelopathy
Primary: Individual Patient Overall Success — 142; 98 participants
N/A N=267 Investigation of the Simplify® Cervical Artificial Disc
Cervical Degenerative Disc Disease
Primary: Number of Participants With Composite Clinical Success (CCS) of Simplify Disc — 68; 132 Participants — p=<.001
Phase 4 N=79 C7-T1 Epidural Steroid Injections Versus Targeted Injection for Treatment of Cervical Radicular Pain
Radicular; Neuropathic, Cervical · Neck Pain
Primary: Percentage of Participants With ≥50% Pain Reduction on the Numeric Rating Score (NRS) for Pain — 60; 72 percentage of participants — p=0.23
N/A N=352 Investigation of the Two Level Simplify® Cervical Artificial Disc
Cervical Degenerative Disc Disorder
Primary: Composite Clinical Success (CCS) Rate of the Simplify® Disc — 153; 105 Participants — p=0.017
N/A N=15 Transcutaneous Electrical Spinal Stimulation to Restore Upper Extremity Functions in Spinal Cord Injury
Spinal Cord Injury Cervical · Upper Extremity Dysfunction
Primary: Graded and Redefined Assessment of Strength, Sensibility and Prehension Test (GRASSP Test) — 4.5; 19.4 score change before and after — p=<0.000
N/A N=231 Outcome Study of Patients Treated With Translational Cervical Plate Used to Treat Degenerative Disc Disease
Degenerative Disc Disease
Primary: Radiographic Fusion — 66; 46; 37; 75 percentage of subjects
N/A N=65 Does Heart Rate Variablity (HRV) Predict Hypotension in Patients Undergoing Cervical Myelopathy Surgery ?
Heart Rate Variability
Primary: Heart Rate Variability (HRV) — 1439; 2191 ms2
Phase 4 N=65 Surgery Prevention by Transforaminal Injection of Epidural Steroids for Cervical Radicular Pain
Pain, Radiating
Primary: Avoidance of Neck Surgery — 24; 20; 3; 6 Participants
N/A N=3 Spinal Cord Stimulation in Spinal Muscular Atrophy
Spinal Muscular Atrophy Type 3 · Spinal Muscular Atrophy Type 4
Primary: Muscle Weakness — 2; 3 Participants
N/A N=104 Interbody Fusion Devices in the Treatment of Cervicobrachial Syndrome
Radiating Pain · Myelopathy · Cervicobrachial Syndrome
Primary: Neck Disability Index — 17.9; 16.7 units on a scale from 0 to 100 — p=0.641
N/A N=74 Dysphagia Following Anterior Cervical Spine Surgery; Steroid vs Saline
Dysphagia
Primary: Swallowing Difficulty — 16; 14; 5; 7 Participants — p=0.036
Phase 4 N=78 Dysphagia Following Anterior Cervical Spine Surgery; Single Dose Steroid vs Saline (DysDexVSSal)
Dysphagia
Primary: Change in the Occurrence of Dysphagia -Bazaz Scale — 2.17; 3.27 score on a scale
N/A N=122 Comparison Between C3-6 Laminoplasty and C3 Laminectomy With Cervical Laminoplasty
Myelopathy Cervical · Kyphosis Post Surgical · Neck Pain
Primary: C2-C7 Lordosis — 11.0; 10.9 °
N/A N=17 Spinal Cord Stimulation to Restore Cough
Spinal Cord Injuries · Spinal Cord Diseases · Paralysis
Primary: Effectiveness of Expiratory Muscle Activation to Generate Large Airway Pressures Characteristic of Normal Cough. — 25; 121 cmH2O — p=<0.05
N/A N=30 Non-invasive Cervical Electrical Stimulation for SCI
Spinal Cord Injuries
Primary: Electromyographic Responses (Active)
N/A N=128 Effect of Topical Corticosteroids on Dysphagia in Anterior Cervical Discectomy and Fusion
Cervical Disc Herniation · Cervical Degenerative Disc Disease · Cervical Spondylotic Myelopathy
Primary: Degree of Dysphagia Patients Experience (Burden) — 100; 100; 50; 75 score on a scale — p=0.394
N/A N=162 Posterior Fossa Decompression With or Without Duraplasty for Chiari Type I Malformation With Syringomyelia
Arnold-Chiari Malformation, Type 1 · Chiari Malformation Type I · Type I Arnold-Chiari Malformation
Primary: The Number of Participants With Surgical Complications — 8; 10 Participants
Phase 3 N=545 Study of Safety & Effectiveness of PRESTIGE® LP Cervical Disc vs. Anterior Cervical Fusion in Cervical DDD
Cervical Degenerative Disc Disease
Primary: Rate of Overall Success — 70.4; 63.2 percentage of participants — p=0.995
N/A N=19 Driving After Cervical Spine Surgery
Cervical Disc Disease
Primary: Change in Number of Total Collisions (TC) — 2 collisions/crashes
N/A N=30 Cervical Activation During Elastic and Manual Resistance
Cervical Pain
Primary: Percent of Peak Activation (%PA) — 51.72; 61.20; 88.1; 80.80 Percentage of Peak Activation (%PA)
N/A N=17 Palliative Strategies in Spinal Cord Injury (SCI)
Spinal Cord Injury
Primary: Muscle Mass Via Dual-Energy X-ray Absortiometry (DEXA)Scan Data — 6104.45; 6355.3 grams — p=.318
N/A N=89 SECURE®-C Cervical Artificial Disc Clinical Study/ SECURE-C Cervical Artificial Disc Postmarket Approval Study
Symptomatic Cervical Disc Disease
Primary: Individual Patient Overall Success — 127; 81; 67 participants
N/A N=98 Preventive Care of Chronic Cervical Pain and Disabilities
Neck Pain
Primary: Neck Pain — 3.8; 3.3; 3.4 cm
N/A N=20 Vertebral Artery and Cerebral Hemodynamics After Various Head Positions & Manipulation in Patients With Neck Pain
Vertebral Artery Dissection · Cerebrovascular Accident · Stroke
Primary: Changes in Blood Flow Through the Vertebral Artery and Posterior Cerebral and Cerebellar Circulation — 15.5; 15.1; 14.7 cm/s
N/A N=345 Safety and Efficacy Study Comparing ProDisc-C to ACDF Surgery to Treat SCDD
Symptomatic Cervical Disc Disease
Primary: Overall Success — 62.8; 53.2; 62.7 % of Subjects
N/A N=203 Radiotherapy of Motor Deficits From Metastatic Epidural Spinal Cord Compression
Metastatic Epidural Spinal Cord Compression
Primary: Number of Participants Showing Improvement or no Further Progression of Motor Deficits at 1 Month Following Radiotherapy — 68; 69 Participants
Phase 4 N=457 Trial of Cilostazol in Symptomatic Intracranial Arterial Stenosis II
Cerebral Infarction · Atherosclerosis
Primary: Number of Participants With Progression of Symptomatic Intracranial Stenosis — 20; 32 participants