Phase 2 N=10 Histopathology Following CCH Injection
Characteristics of Subcutaneous Tissue
Primary: Number of Participants With a Histologic Change in a Tissue Specimen That Was Injected With CCH — 2; 1; 1; 2 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=60 Subcutaneous Fat Reduction in the Submental Area
Body Fat Disorder
Primary: Safety of CoolScupting in the Submental Area — 4 incidence of device- and/or procedure AE
N/A N=63 Cellular Dynamics of Subcutaneous Fat Distribution in Obese Women
Obesity · Metabolic Syndrome
Primary: In Vivo Adipose Cell Formation (Adipogenesis) — -0.3; 1.8; -1.2; 2.1 percent
Phase 4 N=4 Subcutaneous vs. Intramuscular Testosterone
Testosterone Deficiency · Hypogonadism, Male
Primary: Change in Levels of Serum Total Testosterone Concentration — NA; 1043.6; NA; 785.7 ng/dl
Phase 4 N=16 Submental Study (Sequential Treatment Approach)
Body Fat Disorder
Primary: The Proportion of Subjects Who Have at Least a 1-grade Improvement on the Clinician Reported Submental Fat Rating Scale (CR-SMFRS) at the Final Follow-up Visit When…
N/A N=40 Diagnostic Ultrasound for Measuring Fat of the Body
Subcutaneous Fat
Primary: Difference in Thickness of Subcutaneous Fat at Different Anatomic Sites on the Body — .56; .60; .83; 1.65 average fat measurement (cm)
Phase 2 N=19 Double Blind Study to Evaluate the Efficacy of Collagenase Histolyticum in the Treatment of Lipoma
Lipoma
Primary: Percent Change From Baseline in Surface Area of the Lipoma at Six Months — -81.277; 2.053 percentage change from baseline — p=<0.0001
N/A N=15 Effects of Different Support Surfaces on the Properties Skin After Loading
Pressure Ulcers
Primary: Transepidermal Water Loss (TEWL) in g/m2/h on Sacrum, at Baseline — 7.8; 7.7; 7.1 g/m2/h
N/A N=48 Acute Subcutaneous Defibrillation
Ventricular Arrhythmias
Primary: Subjects Will Demonstrate a Successful Defibrillation Outcome if They Have 2 Successful Defibrillation Shocks With the Research System. — 85.7 percentage of success
N/A N=11 Comparative Ultrasound Analysis of Two Hyaluronic Acid Dermal Fillers
Volume Deficiency of the Midface
Primary: Assess and Compare Tissue Aggregation and Visualization of Hyaluronic Acid Fillers by Investigator Using Ultrasound — 10; 1; 7; 9 Participants
N/A N=30 Probe Configuration and Time-Temperature Dose Ranging for Understanding of Skin Lesion Effects
Histological Response of Tissue to Cold
Primary: Biological Tissue Response
N/A N=60 Non-invasive Cooling of Subcutaneous Fat
Fat Disorder
Primary: Change in Fat Layer Thickness of the Treated Flank — -18.7; -22.6; -17.8; -17.5 percent fat layer change
Phase 2 N=48 Adipose Tissue Extract and Platelet-rich Plasma Use for Wound Healing
Wound Healing Disturbance of
Primary: Wound Re-epithelization — 12.34; 10.27; 11.33 days
N/A N=30 Evaluate Patients With Chronic Hepatitis by Three-dimensional Force-controlled Ultrasound Measurement
Fatty Liver
Primary: Subcutaneous Fat in Steatosis Patients — 9.54; 10.48; 5.24; 4.09 cm^3
N/A N=31 Profound Dermal and SubQ Cartridges for the Treatment of Cellulite
Cellulite
Primary: Improvement in Global Aesthetic Appearance of Cellulite in Treated Areas, as Assessed by Study Investigator Evaluations — 11; 7; 4; 16 Investigator Assessments
N/A N=4 Study of Skin and Muscle Parameters Using a Skin Sensor
Skin Wounds
Primary: Measure Temperature at 3 Time Points — 29.89; 31.13; 31.87; 32.02 Degrees Celsius — p=<0.0001
N/A N=15 Structural Fat Grafting for Craniofacial Trauma Using Manual Technique for Processing Fat Graft Material
Facial Injuries
Primary: Soft Tissue Volume After Autologous Fat Grafting Using CT Scans. — 11.4; 7.4; 6.5 milliliters
N/A N=12 Comparing the Effects of Three Different Dressings on the Cutaneous Response of Sacral Skin
Pressure Ulcer Prevention
Primary: Change in Skin Surface Temperature From Baseline — 3.1; 3.8; 3.0; 3.3 °C
N/A N=74 Randomized Controlled Trial of Subcuticular Skin Closure Versus Steri-strip S Closure
Breast Hypertrophy · Abdominal Elastosis · Breast Reconstruction
Primary: Scar Quality at 6 Months Postoperative — 3.8; 2.6 units on a scale
N/A N=22 Cryolipolysis and Subcision for Treatment of Cellulite
Cellulite
Primary: Blinded Rating of the Treatment Area (Cryolipolysis vs. Subcision) With the Best Cosmetic Appearance. — 22.22; 33.33; 44.44 Percentage of participants
N/A N=1,029 Condition of Submental Fullness and Treatment Outcomes Registry
Submental Fullness
Primary: Percentage of Participants With at Least One Treatment-Emergent Adverse Event (TEAE) — 13.2; 8.7; 20.0; 5.2 percentage of participants
Phase 2 N=88 A Study of Subcutaneous Abatacept to Treat Diffuse Cutaneous Systemic Sclerosis
Diffuse Cutaneous Systemic Sclerosis
Primary: Proportion of Participants With at Least One Adverse Events (AEs) or Serious AEs (SAEs) in 1 Year — 35; 40 Participants
N/A N=5 Optical Measurements of the Skin Surface to Infer Distinctions in Myofascial Tissue Stiffness
Tissue Pain
Primary: Skin Stretch Response to Manual Lateral Pull — 0.512; 0.494; 0.508; 0.473 %/mm
N/A N=14 Fat Reduction in the Submandibular/Submental Area
Body Fat Disorder
Primary: Proportion of Accurately Identified Pre-Treatment Photos by a Panel of Blinded Independent Reviewers — 11 photos