Phase 2 N=20 Efficacy of Teriparatide in Diabetic Inactive Charcot Neuroarthropathy of Foot
Diabetic Neuropathic Arthropathy
Primary: SUV Max on PET/CT Scan at 12 Months — 26.1; 22.9 g/ml
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=7 Investigating the Use of Prolia (Denosumab) in the Treatment of Acute Charcot Neuroarthropathy
Charcot Joint of Foot
Primary: Incidence of Treatment-Emergent Adverse Events [Safety and Tolerability] — 0; 7 Participants
N/A N=23 Weightbearing Assessment of Tarsal Instability
Adult-acquired Flatfoot Disorder (AAFD)
Primary: Change in Joint Motion Between Touch-down Bearing Navicular and Full-weight Bearing Navicular — 3.56; 4.36; -0.1666; -0.170 mm
N/A N=60 Metatarsal Phalangeal Joint Deformity Progression - R01
Diabetes Mellitus (DM)
Primary: Change in Metatarsal Phalangeal Joint Angle (Degrees) in People With Diabetes From Baseline and at a 3-year Period — 0.8; -0.1 degrees
N/A N=41 Neurogenic Inflammation in Diabetes
Diabetes Mellitus · Polyneuropathies · Arthropathy, Neurogenic
Primary: Induration Size as a Response to Intracutaneous Candida Albicans. — 4; 6; 5; 4 millimeters — p=0.84
N/A N=11 Do Rocker Bottom Shoes and Ankle-Foot Orthoses Reduce Pain and Improve Mobility for Ankle Osteoarthritis Patients
Ankle Osteoarthritis · Healthy Ankles
Primary: Daily Step Count (# Steps) — 3453; 2399; 3453; 2745 steps
N/A N=20 Reduction and Fixation of Metatarsal Neck Fracture by Metaizeau's Technique
Displaced Metatarsal Neck Fracture
Primary: Time of Union — 5.8 weeks
N/A N=100 Associated Joint Pain With Controlled Ankle Movement (CAM) Walker Boot Wear
Pain · Ankle Injuries
Primary: The Presence and Severity of Secondary Site Pain — 31 Participants
N/A N=22 Iterative Design of Custom Dynamic Orthoses to Reduce Articular Contact Stress
Ankle Fractures · Post-traumatic Osteoarthritis · Osteoarthritis Ankle
Primary: Joint Contact Stress Time Exposure (Model Estimated) — 4.44; 3.97; 4.08; 4.25 MPa-s/gait cycle
N/A N=64 Talocrural Joint Manipulation in Stroke
Stroke
Primary: Overall Stability Index Measurement — 17.5; 9 units on a scale
Phase 2 N=30 Micro-mobile Foot Compression and Diabetic Foot
Diabetes · PAD · Lower Extremity Edema
Primary: Change in Balance From Baseline to 4 Weeks — 0.94; 0.76 cm
Phase 3 N=24 Allograft Transplantation in the Treatment of Osteoarthritis of the Metatarsophalangeal (MTP) Joint of the Great Toe
Osteoarthritis
Primary: Allograft Stability — 0
N/A N=99 Enhancing Diabetic Foot Education by Viewing Personal Plantar Pressures
Diabetes Mellitus · Diabetic Neuropathies · Foot Complications
Primary: Foot Care Behavior Score — 29; 36; 33; 42 Participants — p=0.0770
N/A N=48 Prospective Subtalar, Double, or Triple Arthrodesis Study With CCS Screws
Post-traumatic Osteoarthritis, Unspecified Ankle and Foot · Localized, Primary Osteoarthritis of the Ankle and/or Foot
Primary: Number of Participants With Intraoperative Complications — 0 Participants
N/A N=40 Cryoneurolysis for Improvements in Pain, ADL and QOL in Patients With Ankle Osteoarthritis
Ankle Osteoarthritis
Primary: FAOS - PAIN — 20.8 score on a scale
Phase 3 N=30 Effects of CHONDRON (Autologous Chondrocytes) With Ankle Cartilage Defect
Articular Cartilage Defects of Ankle Joint
Primary: Average Change From Baseline in American Orthopedic Foot and Ankle Society(AOFAS) at 12 Months Post-surgery — 16.93 scores
N/A N=21 Cerebral Palsy: Ankle Foot Orthoses - Footwear Combinations
Cerebral Palsy (CP)
Primary: Change in Baseline Gait Profile Score (GPS) at 3 Months-individual Lower Extremity Joint Kinematics — 0.41; -0.48 units on a scale — p=0.36
N/A N=3 Peak Plantar Pressures While Wearing a Carbon Fiber Off Loading Orthoses
Diabetes Mellitus · Peripheral Neuropathy · Orthotic Device
Primary: Peak Plantar Pressure — 75.3; 14.2; 14.5; 22.8 Newtons per squared centimeters
N/A N=148 A Longitudinal Outcomes Study of the Subchondroplasty® Procedure in the Foot/Ankle
Insufficiency Fractures · Stress Fracture · Stress Fracture, Ankle, Foot and Toes
Primary: Foot Function Index-Revised (FFI-R) Short Form Score at 24 Months — 42.8; 43.0; 39.6 Percentage scale
N/A N=78 Effects of Foot Muscle Strengthening in Daily Activity in Diabetic Neuropathic Patients
Diabetic Neuropathies
Primary: Daily Physical Activity — 8744; 7373 number of steps per week
N/A N=273 Treatment Outcomes for Ankle Arthritis
Osteoarthritis
Primary: Musculoskeletal Functional Assessment (MFA) — -12.5; -15.0 units on a scale
N/A N=45 Ankle Robot to Reduce Foot Drop in Stroke
Stroke · Foot Drop
Primary: Gait Velocity During Self-selected Overground Walking — 0.48; 0.48; 0.54; 0.56 CM/SEC
Phase 2 N=175 Preventing Diabetic Foot Ulcers Through Cleaner Feet
Diabetic Foot Ulcer
Primary: Time to New Foot Complication Among All Randomized Participants — 12; 14 Participants
N/A N=13 Compression Nail for Tibiocalcaneal Arthrodesis
Subtalar Arthritis · Ankle Arthritis
Primary: Pain Assessment — 52.73; 33.00; 17.00; 21.25 score on a scale
N/A N=65 Validation of Plantar Orthoses for Abnormal Plantar Arch Using a New Non-invasive Clinical Imaging System
Flat Feet · High Arched Foot
Primary: Change From Baseline in Body's Postural Symmetry Index(SSIM Gray) at 2 Months — -0.031; 0.010 score on a scale
N/A N=64 Mid-term Outcomes of First MTP Arthroplasty With Primus™ FGT Implant.
Hallux Limitus of Left Great Toe · Rheumatoid Arthritis · Arthritis of 1st Metatarsophalangeal Joint
Primary: AOFAS Hallux-MTP-IP Score - Overall — 88.9 units on a scale
N/A N=30 Patient Specific 3D Printed Diabetic Insoles to Reduce Plantar Pressure
Diabetes
Primary: Plantar Pressure - Standard of Care — 202.71 kPa
N/A N=20 Validation of a Novel Foot Offloading Device
Plantar Fasciitis, Chronic · Heel Pain Syndrome · Fat Pad Syndrome
Primary: Change in Foot Pain From Screening/Baseline Visit to 4 Week Visit as Reported on the Pittsburgh Foot Survey. — 2.930 Score on a scale — p=0.0796
N/A N=62 Factors Associated With Radiographic Pathophysiology for Trapeziometacarpal Arthrosis in Patients Not Seeking Care for This Condition
Trapeziometacarpal Arthrosis
Primary: Factors Associated With Eaton Classification of Trapeziometacarpal Arthrosis: Age — 61; 66; 75 Years
N/A N=33 Improving Mobility in Peripheral Artery Disease Using an Ankle Foot Orthosis
Peripheral Artery Disease
Primary: Maximum Walking Time From the Gardner Graded Treadmill Protocol — 117.7; 197.5; 188; 339.9 Seconds