Phase 2 N=8 Botulinum Toxin for the Management of Chronic Orchialgia
Chronic Testicular Pain
Primary: Visual Analog Scale for Pain Score — 59.3; 30.3; 55.0; 75.0 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=154 Near-Infrared Spectroscopy for Pediatric Acute Scrotum and Testicular Torsion
Acute Scrotum · Testicular Torsion
Primary: Median NIRS Delta %StO2 — 2.0; -1.7 percentage of StO2
Phase 4 N=50 Post-operative Pain Control of Testicular Sperm Extraction Using Liposomal Bupivacaine
Male Infertility
Primary: Pain Scores 48 Hours After Surgery — 118.4; 98.2 Scores*Hour — p=0.41
N/A N=440 Acupuncture for Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Primary: Proportion of Responders at the End of 8-week — 60.6; 36.8 percentage of participants
N/A N=423 Neuropathic Pain After Orchidectomy and Sex Reassignment Surgery
Neuropathic Pain · Phantom Pain · Sex Reassignment Surgery
Primary: Incidence of Phantom Pain — 6; 0 Participants — p=0.013
Phase 2 N=17 An Open-Label Study of CC-10004 for Chronic Prostatitis/Chronic Pelvic Pain Syndrome
Prostatitis · Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Primary: Global Response Assessment — 2 participants
N/A N=6 Investigation of TEST (Transcranial Electric Stimulation Therapy) for Chronic Pain
Chronic Pain
Primary: Feasibility Will be Assessed by the Percent of Participants Who Complete — 6 Participants
Phase 2 N=13 Clomiphene Citrate for the Treatment of Low Testosterone Associated With Chronic Opioid Pain Medication Administration
Hypogonadism · Opioid-Related Disorders · Male Infertility
Primary: Serum Total Testosterone (Change From Baseline) — 322.5; 179.8 ng/mL
Phase 2 N=84 Effects of Testosterone Replacement on Pain Sensitivity and Pain Perception
Pain · Hypogonadism
Primary: Brief Pain Inventory (BPI) at Week 14 — 10.2; 9.7; 5.3; 5.1 units on a scale
N/A N=10 HOP-2A - Intratesticular Hormone Levels
Healthy · Male Infertility · Prostate Disease
Primary: Intratesticular Hormones in Normal Men — 486; 3.0; 3.7; 0.20 ng/mL
Phase 2 N=15 Testosterone Replacement for Male Opioid Agonist Maintained Patients
Chronic Pain · Opioid Addiction · Symptomatic Hypogonadism
Primary: Number of Participants Demonstrating Abstinence — 5; 4 Participants
Phase 4 N=20 Effect of Nicotine on Chronic Pelvic Pain
Pelvic Pain
Primary: Pain Score — 7.1; 6.4; 6.9 Units on a scale
Phase 2 N=40 ITT4 Intratesticular Hormonal Milieu in Man (ITT4)
Healthy Males
Primary: Intratesticular Testosterone (IT-T) Level — 14; 3.7; 1.7; 18.4 ng/mL — p=<0.05
Phase 2 N=40 HOP-3 Manipulation of the Intratesticular Hormonal Milieu With Exogenous Testosterone
Healthy Males
Primary: Serum Testosterone (T) — 0.43; 1.5; 3.7; 8.4 nmol/liter — p=<0.05
Phase 2 N=26 Transcranial Direct Stimulation in Chronic Pelvic Pain
Pelvic Pain · Healthy
Primary: Pain Assessment — -2.375; -1.625 units on a scale
Phase 3 N=139 Efficacy Study of a Standardized Pollen Extract Preparation (Cernilton) to Treat Inflammatory Chronic Prostatitis-Chronic Pelvic Pain Syndrome (CP-CPPS)
Chronic Prostatitis · Chronic Pelvic Pain Syndrome
Primary: Symptomatic Improvement in the Pain Domain of National Institutes of Health-Chronic Prostatitis Symptom Index (NIH-CPSI) — 47; 33 participants — p=<0.05
N/A N=29 ITU Treatment for Chronic Epicondylitis Musculoskeletal Pain Reduction
Tennis Elbow
Primary: Percentage of Patients Reporting at Least 25% Overall Pain Reduction — 88 percentage of patients with less pain
Phase 2 N=62 An Efficacy And Safety Study Of Tanezumab For The Treatment Of Pain Associated With Chronic Abacterial Prostatitis
Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Primary: Change From Baseline in Average Daily Pain Score at Week 6 — 5.5; 5.6; -1.4; -1.0 units on a scale
N/A N=143 Study Evaluating the Impact of Mesh Pore Size on Chronic Pain After Lichtenstein Hernioplasty
Inguinal Hernia
Primary: Chronic Pain — 34.3; 46.3 percentage of patients with pain
Phase 4 N=353 Chronic Pain Risk Associated With Menstrual Period Pain
Cystitis, Interstitial · Dysmenorrhea · Migraine Disorders
Primary: Change in Participant Bladder Pain Sensitivity From Baseline. — 38.2; 37.0; 41.2; 47.9 score on a scale — p=.02
Phase 2 N=14 Pediatrics Testotoxicosis Study [Bicalutamide Anastrozole Treatment for Testotoxicosis]
Puberty, Precocious
Primary: Change in Growth Rate (cm/Year) — -1.62 cm/year — p=0.278
N/A N=77 Preoperative Etanercept Before Inguinal Hernia Surgery
Inguinal Hernia · Postoperative Pain
Primary: Numerical Rating Scale Pain Score — 3.3; 3.9 units on a scale
Phase 3 N=31 Testosterone Replacement Therapy in Chronic Spinal Cord Injury
Spinal Cord Injury · Hypogonadism
Primary: Dual Energy X-ray Absorptiometry (DXA) Assessment of Lean Tissue Mass (LTM) — 53.1; 50.5 kilograms — p=<0.01
Phase 3 N=324 Efficacy & Safety Study of Pregabalin to Treat Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
Primary: Decrease in the NIH-CPSI Total Score by at Least 6 Points — 103; 38 Participants
N/A N=10 Role of Home-based Transcutaneous Electrical Acustimulation for Treatment of Pain in Patients With Chronic Pancreatitis
Chronic Pancreatitis
Primary: Proportion of Approached Individuals Who Met Eligibility Criteria — 12 Participants
Phase 3 N=74 Gabapentin for Post-Operative Pain Control and Narcotic Reduction in Scrotal Surgery
Non-obstructive Azoospermia
Primary: Pain Score as Measured by the NRS-11 Scale — 1.91; 3.05; 2.27; 3.24 scores on a scale — p=0.01
N/A N=570 Assessing the Rates of Major Complications in Combined Mini-incision Microscopic Varicocelectomy
Varicocele
Primary: Recurrent Varicocele — 2; 16 participants
N/A N=25 Perioperative Hypogonadism in Men Undergoing Radical Cystoprostatectomy for Bladder Cancer
Bladder Cancer · Low Testosterone Levels
Primary: Number of Hypogonadism in Participants Based on Serum Testosterone 90 Days Post Radical — 6 participants
N/A N=220 Pain, Sexual Dysfunction, and Depression in Hemodialysis Patients
End Stage Renal Disease · Sexual Dysfunction, Physiological · Pain
Primary: Change in Pain, Sexual Dysfunction, and Depression Symptoms — -3.12; -3.7; 0.62; 0.71 units on a scale
N/A N=14 Pancreatic Endotherapy for Refractory Chronic Pancreatitis
Pancreatic Duct Stone · Pancreatic Duct Stricture · Pancreatic Duct Dilatation
Primary: Percent Change in Average Daily Pain Score on the Numeric Rating Scale — -36.6; -53.7 Percent Change