N/A N=444 Study of A New Contact Lens Cleaning and Disinfecting Solution
Vision Disorders
Primary: Percentage of Eyes With > Grade 2 Slit Lamp Findings — 4; 0 eyes
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=295 Vistakon Investigational Multi-purpose Contact Lens Care Solution.
Contact Lens Wear
Primary: Slit Lamp Findings (SLF) — 0; 0; 0; 0 eyes (2 per subject)
N/A N=300 Investigational Multi-purpose Contact Lens Care Solution.
Contact Lens Wear
Primary: Slit Lamp Findings — 11; 16; 0; 0 Subjects Eyes
N/A N=14 Contact Lens Insertion and Removal in a Senior Subject Demographic
Visual Acuity
Primary: Overall Success Rate of Insertion and Removal of a Contact Lens — 85.7 Percentage of eyes
N/A N=134 Effectiveness of a Marketed One-Step Peroxide Lens Care Solution in Symptomatic Contact Lens Wearers
Refractive Error
Primary: Mean Change From Baseline in Investigator Rated Lid Papillae Maximum Score at Day 90 — 2.3; 2.3; 2.2; 2.2 units on a scale
Phase 3 N=30 Comparison of Lens Care Regimens With a Silicone Hydrogel Lens (Emerald)
Myopia
Primary: High Contrast Visual Acuity — -0.04; -0.04 logMAR
N/A N=28 A Clinical Evaluation of Two Contact Lenses Used With Three Care Systems
Myopia
Primary: Overall Comfort — 86.0; 81.6; 81.0; 87.7 units on a scale
N/A N=56 A Range of Contact Lenses and Care System Combinations
Contact Lens Solutions
Primary: Biomicroscopy - Conjuctival Hyperaemia — 0.95; 0.94; 0.91; 0.91 units on a scale
N/A N=236 Clinical and Laboratory Evaluation of 3 Contact Lenses With 4 Contact Lens Solutions
Contact Lens Solutions
Primary: Overall Comfort Score (Senofilcon A Lens) — 64.42; 59.73; 63.75; 63.47 units on a scale
N/A N=446 Clinical Evaluation of the Long-Term Effects of Contact Lens Care Systems
Myopia
Primary: Average Daily Wear Time — 13.57; 13.30 Hours
N/A N=132 Clear Care® Plus vs. PeroxiClear™
Refractive Error
Primary: Mean Residual Peroxide at Day 30 — 229.7; 26.2 parts per million (ppm)
N/A N=25 Contact Lens Adaptation in Neophytes
Contact Lens Comfort
Primary: Between-Group Difference in Eye Comfort as Measured by the Ocular Surface Disease Index (OSDI) — 10.8; 16.3 Units on a Scale — p=0.83
N/A N=30 BIOCLEAN FIRST CARE EX in Combination With Biofinity Lens
Myopia
Primary: Ocular Health - Corneal Staining — 38; 35; 18; 20 Eyes
N/A N=22 Evaluation of Silicone Hydrogel Lens Wettability With Marketed Lens Care Solutions
Contact Lens Wear
Primary: Ex Vivo Contact Angle — 104.8; 104.9; 103.3 degrees
N/A N=121 CLEAR CARE® PLUS for Presbyopic Contact Lens Wearers
Presbyopia
Primary: Contact Lens Dry Eye Questionnaire-8 (CLDEQ-8) Score at Day 30 — 12.6; 14.8 units on a scale — p==0.0073
N/A N=32 A Clinical Comparison of Marketed Lens Care Solutions With Avaira Lens Brand
Corneal Staining
Primary: Corneal Staining Severity — 0.01; 0.01; 0.02; 0.01 units on a scale
N/A N=295 A Study to Evaluate the Safety and Effectiveness of a Contact Lens Cleaning and Disinfecting Solution
Refractive Ametropia
Primary: Overall Comfort Averaged Over All Follow-up Visits — 91.7; 90.7 score on a scale
N/A N=61 Evaluation of Comfilcon A and Senofilcon A Lenses
Myopia
Primary: Subjective Responses for Comfort Rated on a 0-100 Visual Scale. — 86; 87; 89; 91 units on a scale
Phase 4 N=50 Corneal and Conjunctival Sensitivity and Staining Study
Myopia · Hyperopia
Primary: Corneal Sensitivity — 26.9; 25.5 percent CO2
N/A N=70 Comparative In-Vivo Wetting Characteristics of Silicone Hydrogel Materials With Selected Lens Care Systems
Myopia · Astigmatism · Refractive Error
Primary: Mean Ex-Vivo Total Lipid Uptake Per Lens — 7.198; 35.879 micrograms
N/A N=79 An Evaluation of Marketed Contact Lens Disinfectant Systems on Eyelid Tissues
Myopia
Primary: Maximum Papillae — 1.50; 1.00; 1.50; 1.00 Units on a scale
Phase 3 N=246 Safety and Acceptability of Using a Rewetting Drop With Contact Lens Wear
Ametropia
Primary: Best Corrected Visual Acuity — 0.65; 1.33; 98.06; 98.67 Percentage of Participants
N/A N=48 The Clinical Performance of the Biofinity Contact Lens (Comfilcon A) With Two Lens Care Systems
Myopia
Primary: Conjunctival Hyperaemia — 0.84; 0.87; 0.87; 0.87 units on a scale
N/A N=191 Handling Comparison Between Two Contact Lens Types
Presbyopia
Primary: Overall Lens Handling Using the Contact Lens User Experience(CLUE) TM Questionnaire. — 53.44; 55.81; 61.70; 60.23 units on a scale
N/A N=591 Alcon Multi-Purpose Disinfecting Solution Versus Renu Fresh Multi-Purpose Solution in Symptomatic Contact Lens Wearers
Symptomatic Contact Lens Wearers
Primary: Likert Statement: When I Use This Solution, I Can Comfortably Wear my Lenses. — 3.9; 3.8 Units on a scale
N/A N=42 Comparison of a New Abbott Medical Optics (AMO) Multi-Purpose Solution (MPS) to Existing Contact Lens Regimens
Normal Contact Lens Wearers
Primary: Corneal Staining — 184; 46.6; 77.8 units on a scale
N/A N=372 Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution
Refractive Error · Myopia · Hyperopia
Primary: Likert Scale Questionnaire Item: "I Can Comfortably Wear my Lenses" — 4.2; 4.4 units on a scale
N/A N=36 Three Daily Wear Monthly Replacement Silicone Hydrogel Contact Lenses With Two Multi-purpose Disinfecting Solution Combinations
Refractive Errors
Primary: Average Percent Area of Corneal Staining — 2.93; 0.45; 6.06; 3.52 percentage of area
N/A N=60 Evaluating Two Multifocal Daily Disposable Contact Lenses
Presbyopia
Primary: Comfort Just After Lens Insertion — 9.1; 9.2 score on a scale
Phase 4 N=73 Direct Application of Systane Complete to Contact Lenses
Dry Eye · Contact Lens Complication
Primary: Difference in Ocular Surface Damage as Measured by the Brien Holden Vision Institute (BHVI Grading Scale) at Two Weeks — 0.44; 1.08; 0.83 Score on a Scale — p=0.30