Phase 3 N=167 Maintenance Intravenous Fluids in Children
Hyponatremia
Primary: Incidence of Hyponatremia (Defined as Serum Sodium Less Than 130 mmol/L) — 1; 2; 8 participants — p=<0.05
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=148 Subcutaneous Rehydration Compared to Intravenous Rehydration
Dehydration
Primary: Mean Total Volume of Fluid Administered at a Single Infusion Site, From the Start to the Cessation of Fluid Administration, for All Randomized Participants — 365.0…
Phase 4 N=147 Efficacy and Safety of a New Oral Rehydration Solution (Hipp ORS 200 Apple) in Children With Acute Gastroenteritis
Diarrhea
Primary: Number of Participants That Were Successfully Rehydrated — 57; 49 Participants — p=0.28
Phase 4 N=34 Effect of Coconut Water on Hydration Status in Pediatric Population
Sports Nutrition
Primary: To Determine the Effect of AC vs EO on Hydration Status in Adolescents Who Perform Physical Exercise of Aerobic Competition. — 53; 36; 15; 32 Number participants…
N/A N=76 Ultrasound of the Inferior Vena Cava (IVC) and Dehydration Status in Pediatric Emergency Patients
Dehydration
Primary: Maximum IVC Diameter — 38; 64 mm
Phase 3 N=396 Next Generation ORS: Comparing ORS With Calcium vs Standard ORS in Reducing Severity of Acute Watery Diarrhea
Diarrhea · Cholera
Primary: Stool Output — 4769; 4742; 1688; 1704 gram — p=0.9941
Phase 4 N=52 Study of Subcutaneous Rehydration With Recombinant Human Hyaluronidase for Infants and Children
Dehydration
Primary: HYLENEX-facilitated Subcutaneous (SC) Rehydration Success — 43 participants
N/A N=251 Nutritional Education and the Prevention of Iron Depletion in Children 9 Months to 2 Years
Iron Deficiency
Primary: The Primary Outcome is Iron Depletion, and Will be Defined as Serum Ferritin <10 mcg/L. — 64; 71; 13; 10 participants — p=0.42
Phase 2 N=83 IV Glucose for Dehydration Treatment
Dehydration
Primary: Measurement of Serum Ketones Before and After Administration of Intravenous Fluids for Acute Gastroenteritis — 1.10; 2.39 mmol/L — p=0.0003
Phase 3 N=1,389 Randomized Control Trial of Fluid Therapy for Pediatric Diabetic Ketoacidosis
Cerebral Edema · Diabetic Ketoacidosis
Primary: the Number of Participants With Glasgow Coma Score (GCS) < 14 Within the First 24 Hours of Treatment for Diabetic Ketoacidosis (DKA) — 10; 11; 11; 16 Participants — p=0.34
N/A N=71 Oral Zinc for the Treatment of Acute Diarrhea in US Children
Diarrhea · Gastroenteritis
Primary: Duration of Diarrhea in Acute Diarrheal Illnesses in a Developed Nation While Taking Zinc or Placebo. — 73; 72; 48; 76.8 Hours — p=0.88
N/A N=21 Water Induced Thermogenesis in Obese Children
Obesity
Primary: Post-drinking Metabolic Rate — 1487 kcal/d
N/A N=20 Cerebral Edema in Pediatric Diabetic Ketoacidosis
Diabetic Ketoacidosis
Primary: Cerebral Edema Measured by MR Imaging (Apparent Diffusion Coefficient) — 36; 48 mm^2/sec
N/A N=66 0.9% NaCl/Dextrose 5% vs 0.45% NaCl/Dextrose 5% as Maintenance Intravenous Fluids in Critically Ill Children
Hyponatremia
Primary: Serum Sodium Levels in Both Groups — 137.8; 140.0 mEq/L — p=0.04
Phase 3 N=258 Hypotonic Versus Isotonic Parenteral (HIP) Fluid Trial
Hyponatremia · Hypernatremia
Primary: Hospital Acquired Acute Plasma Sodium Derangements (Hypo- or Hypernatremia)
N/A N=3,190 Promoting Water Consumption for Prevention of Overweight in School Children in a Controlled Intervention Trial
Overweight
Primary: Overweight — 683; 385 participants — p=<0.05
N/A N=35 The Effect of Acute Mild Dehydration on Blood Pressure Control
Mild Dehydration
Primary: Blood Pressure Variability — 2.6; 2.5 mmHg
Phase 4 N=17 Descriptive Study of Cardiac Output During Rehydration With Recombinant Human Hyaluronidase in Pediatrics
Dehydration · Cardiac Output · Pediatrics
Primary: Cardiac Output Trends
N/A N=563 Healthy Hydration Pilot in Elementary Schools
Hydration · Dental Caries · Body Mass Index
Primary: Recruitment of Three 4th or 5th Grade Student Students to Assume the Role as Student Ambassador. — 3; 0 Participants
Phase 3 N=78 Variation in Natremia Using Two Different Maintenance Intravenous Fluids in Postsurgical Hospitalized Children
Hyponatremia
Primary: Change in Sodium Levels — 139.9; 138.1; 138.1; 138.2 mEq/L — p=0.030
Phase 3 N=31 Study to Evaluate the Efficacy and Safety of Racecadotril in Children Aged 3 to 60 Months Suffering From Acute Diarrhea
Diarrhea, Infantile
Primary: Duration of Diarrhea (Hours) Between the Start of Treatment Until Last Diarrheal/Watery Stool Before Recovery or End of Study Treatment (Treatment Duration Maximal 5…
N/A N=129 Parenteral Hydration in Advanced Cancer Patients
Advanced Cancer · Dehydration
Primary: Participant Reduced Symptom Burden — -3.3; -2.8 units on a scale
Phase 3 N=143 Micronutrient Sprinkles in a Daycare Center
Diarrhea · Respiratory Infection
Primary: Proportion of Children of Diarrhea Episodes — 19.1; 14.7 percentage of participants
N/A N=160 Effect of Intraoperative Crystalloid Volume on Postoperative Vomiting
Postoperative Vomiting
Primary: Postoperative Vomiting — 11; 9; 66; 68 participants — p=0.05
N/A N=92 Water Up@ At Home: An Intervention to Replace Sugary Drinks With Water
Diabetes Mellitus, Type 2
Primary: Change in Sugary Drink Consumption for Parents — 12; 14.29; 4.57; 8.57 oz/day — p=0.15
N/A N=300 Postoperative Vomiting in Children - Is Dextrose an Effective Prophylactic Anti-emetic?
Postoperative Vomiting
Primary: Number of Participants With Postoperative Vomiting Between 0 to 2 Hours — 11; 5 Participants
Phase 3 N=124 Controlled Study to Evaluate the Efficacy and Safety of Racecadotril in Infants, Children and Adolescents With Acute Diarrhea
Diarrhea
Primary: Duration of Diarrhea (Hours) Between the Start of Treatment Until Last Diarrheal/Watery Stool Before Recovery or End of Study Treatment (Treatment Duration Maximal 5…
Phase 3 N=546 Corticosteroids for Children With Febrile Urinary Tract Infections
Acute Urinary Tract Infection · Urinary Tract Infection
Primary: The Distribution of Children With Renal Scarring at the Outcome Dimercaptosuccinic Acid (DMSA) Renal Scan — 12; 22; 111; 109 Participants — p=0.16
N/A N=198 Discharge Medication Counseling in Hospitalized Children
Medication Management
Primary: Observed Dosing Accuracy — 3.3; 1.0 percent difference — p=<0.001
Phase 2 N=12 Treating Respiratory Emergencies in Children Study
Asthma in Children
Primary: Proportion of Patients Admitted to the Hospital in Each Group — 6; 15 Participants