Phase 2 N=64 CBD for Dental Pain
Odontalgia · Toothache
Primary: Intra-group VAS Pain Intensity and Maximum Pain Relief — 63; 69; 63; 21 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=115 Dental Pain Study of Analgesics in Patients Undergoing Molar Removal
Dental Pain
Primary: Sum Pain Intensity Difference Scores — -2.4292; -68.0778; -68.3533; -93.3645 score on a scale
Phase 2 N=269 A Dental Pain Study to Test the Effectiveness of a New Pain Reliever Medicine
Pain
Primary: Analgesic Efficacy From 0 to 6 Hours After the Dose Using the Time-weighted Sum of Pain Intensity Difference (SPID 0-6) — 4.37; 20.75; 8.95; 20.56 units on a scale…
Phase 2 N=235 Efficacy Of PF-05089771 In Treating Postoperative Dental Pain
Postoperative Dental Pain
Primary: Total Pain Relief From 0 to 6 Hours (TOTPAR[6]) — 6.94; 6.21; 7.00; 14.43 units on a scale
Early Phase 1 N=114 Pre-operative Analgesics for Postoperative Pain Relief After Dental Treatment
Pain, Postoperative · Analgesia
Primary: Postoperative Pain, as Measured by Wong-Baker Facial Rating Pain Scale ,After Routine Dental Treatment — 20; 20; 7; 11 Participants
Phase 3 N=256 Ibuprofen Extended-Release Dental Pain Study
Pain · Post-Operative Pain · Third Molar Extraction
Primary: Analgesic Efficacy, as Measured by the Sum of Pain Intensity Differences (SPID) Scale — 14.80; 0.40 Units on a scale — p=<0.0001
Phase 3 N=374 A Dental Pain Study Comparing The Analgesic Efficacy Of Ibuprofen/Caffeine
Pain
Primary: Time Weighted Sum of Pain Relief Rating (PRR) and Pain Intensity Difference (PID) Scores From 0 to 8 Hours Post-dose (SPRID 0-8): Ibuprofen + Caffeine Versus Ibuprofen…
Phase 2 N=153 Study of Buprenorphine HCl Buccal Film in the Treatment of Dental Pain
Dental Pain
Primary: Sum of Pain Intensity Difference From Baseline to 8 Hours — 6.016; 11.867; 11.282; 5.283 units on a scale — p=.4739
Phase 4 N=300 Post-operative Dental Pain Study Comparing Analgesic Efficacy
Post-surgical Dental Pain
Primary: Sum of Pain Relief and Pain Intensity Differences From 0 to 6 Hours (SPRID 6 Hours) — 10.60; 5.87; 3.35 Units on a scale — p=0.0004
N/A N=73 The Effects of Dexamethasone on the Time to Pain Resolution in Dental Periapical Abscess
Dental Research · Pharmaceutical Preparations, Dental
Primary: Decrease Time of Oral Pain — 9; 9; 5; 4 score on a scale
Phase 3 N=316 Study Evaluating A Novel Ibuprofen Formulation In The Treatment Of Dental Pain
Pain
Primary: Time-weighted Sum of Pain Relief Rating and Pain Intensity Difference From 0-8 Hours (SPRID 0-8) — 5.4; 29.8 Units on a scale — p=<0.001
Early Phase 1 N=46 Pain Management in Teeth With Reversible Pulpitis
Reversible Pulpitis · Ibuprofen
Primary: Change in Pain Intensity From Baseline (Pre-Operative) to Immediately During the Procedure (Day 0), Measured by the Visual Analogue Scale (VAS) — 5.05; 0.64 score on a…
Phase 2 N=254 Study of Naproxen Capsules to Treat Dental Pain
Dental Pain
Primary: Analysis of Total Pain Relief (TOTPAR) Over 0 to 12 Hours (TOTPAR-12) After Time 0 — 25.868; 31.948; 24.373; 28.549 units on a scale — p=<0.001
Phase 3 N=118 The Efficacy of a Dentifrice in Providing Relief From the Pain of Dentinal Hypersensitivity
Dentine Hypersensitivity
Primary: Mean Change From Baseline in Evaporative Air Sensitivity Pain Response on a Schiff Sensitivity Scale at Week 8 — -0.9; -0.5 Score on a scale — p=<0.0001
Phase 3 N=218 Study Evaluating A Novel Ibuprofen Formulation In The Treatment Of Dental Pain
Pain
Primary: Time-weighted Sum of Pain Relief Rating With Pain Intensity Difference From 0 to 6 Hours (SPRID 0-6) — 2.8; 20.0; 17.1 units on a scale — p=<0.001
Phase 2 N=202 Study of Diclofenac Capsules to Treat Dental Pain
Dental Pain
Primary: Total Patient Pain Relief Over 0 to 12 Hours. — 17.770; 16.893; 14.685; 5.486 units on a scale — p=<0.001
Phase 4 N=401 Post-operative Dental Pain Study Comparing Two Different Dosage of Analgesic Efficacy
Post-surgical Dental Pain
Primary: Sum of Pain Relief and Pain Intensity Differences From 0 to 6 Hours (SPRID 6 Hours) — 16.08; 12.42; 4.63 Score on a scale — p=0.0009
Phase 3 N=113 Clinical Efficacy of a Toothpaste in Providing Relief From the Pain of Dentinal Hypersensitivity
Dentine Hypersensitivity
Primary: Change From Baseline in Evaporative Air Sensitivity Pain Response on a Schiff Sensitivity Scale at Day 14 — -1.20; -0.37 Score on a scale — p=<0.0001
Phase 2 N=403 Study of Long-Acting Acetaminophen in Postoperative Dental Pain
Dental Pain
Primary: Time Weighted Sum of Pain Intensity Difference (PID) Over 10 Hours (SPID 0-10) — 5.745; 30.986 units on a scale — p=<0.001
Phase 2 N=110 A Study of Acetaminophen for Post Surgical Dental Pain
Pain, Postoperative · Dental Pain
Primary: Sum of Pain Intensity Difference From 0 to 24 Hours (SPID24) Based on the 11 Point Numeric Pain Rating Scale — -96.80; -100.69; -74.96 score on a scale — p=0.0258
Phase 3 N=540 To Evaluate the Safety and Efficacy of Acetaminophen 650 mg and 1000mg in Dental Pain After Surgery
Pain
Primary: Overall Analgesic Efficacy - Sum of Pain Intensity Difference and Pain Relief Scores Over Six Hours (SPRID6) — 529.4; 427.3; 60.0 units on a scale — p=<0.001
Phase 3 N=306 Evaluation of the Efficacy and Safety of Diclofenac HPBCD 25, 50 mg/ml in the Treatment of Post-surgical Pain Following Dental Surgery
Dental Pain
Primary: Pain Intensity Difference (PID) on a 0-100 VAS — 36.5; 37.3; 37.7; 12.3 mm — p=< 0.001
Phase 4 N=211 Study Comparing the Efficacy of Two Ibuprofen Formulations
Pain
Primary: Time to Meaningful Pain Relief — 45.4; 63.6 minutes — p=<0.001
Phase 2 N=203 Phase 2 Study of Indomethacin Capsules to Treat Dental Pain
Dental Pain
Primary: Total Patient Pain Relief Over 0 to 8 Hours. — 10.794; 12.564; 14.822; 3.019 units on a scale — p=<0.001
Phase 4 N=65 Preemptive Analgesia With Celecoxib for Acute Dental Pain Management
Pain, Postoperative
Primary: Pain as Assessed by a Visual Analogue Scale (VAS) — 4; 2.33 score on a scale
Phase 3 N=588 A Study to Asses the Effect of MK0663 in the Treatment of Patients With Postoperative Dental Pain (0663-092)
Postoperative Dental Pain
Primary: Total Pain Relief Score Over the First 6 Hours Post the Initial Day 1 Dose of the Study Medication (TOPAR6) — 5.08; 16.10; 15.73; 15.67 Units on a Scale — p=<0.001
Phase 3 N=678 Ibuprofen/Acetaminophen Versus Nurofen Plus® and Panadeine® Extra Dental Pain Study
Post-operative Pain
Primary: Change From Baseline in Area Under the Curve (AUC) of Pain Intensity and Relief Scores (SPRID) — 2.68; 3.30; 2.62; 1.93 units on a scale*hour — p=<0.0001
Phase 3 N=321 Nefopam/Paracetamol Fixed Dose Combination in Acute Pain After Impacted Third Molar Extraction
Acute Pain
Primary: Ranked Endpoints : 1. Sum of Pain Intensity Differences at 6 Hours (SPID0-6h) — 8955.4; 8458.0; 5290.7 score on a scale — p=0.0031
Phase 3 N=626 The Efficacy of a Toothpaste to Reduce Sensitivity
Dentin Hypersensitivity
Primary: Hypersensitivity Tactile(Yeaple Probe) — 19.81; 13.94 units on a scale — p=0.05
Phase 2 N=75 Injectable Diclofenac for the Prevention of Post-operative Dental Pain
Pain
Primary: Area Under the Curve (AUC) of the Pain Scores. — 6843; 8832; 9998; 7290 mm*minutes