N/A N=30 Diagnostic Device for the Assessment of Pulpal Blood Flow
Dental Pulp Test
Primary: Subjective Tooth Assessment: Number of Teeth With Normal and Abnormal Pulp — 111; 32 Teeth
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=169 Calcium Hydroxide, Mineral Trioxide Aggregate and Biodentine (Trademark) as Direct Pulp Capping of Permanent Teeth
Caries · Dental Pulp Exposure
Primary: Parameters Evaluated After Treatment — 19; 19; 25; 3 Participants
N/A N=98 Clinical Comparison of Vital Pulp Capping Restorative Protocols
Deep Dental Caries
Primary: Success Rate Based on Pulp Vitality Tests (Vital/Non Vital) — 96.2; 100; 100; 86 Percentage of success rate — p=>0.1
N/A N=4 Nanodiamond Modified Gutta Percha (NDGP) Composite for Non-surgical Root Canal Therapy (RCT) Filler Material
Dental Pulp Diseases · Dental Pulp Necrosis · Nerve Root Pain Nec
Primary: Percent Reduction in Apical Radio-lucency — 17.4; 27.1 % Change in Diameter (mm)
N/A N=488 A Comparative Study of Papacarie® and the Conventional Method for Dental Caries Treatment
Dental Caries · Secondary Dental Caries · Personal Satisfaction
Primary: Number of Participants With Treatment Failure — 2; 2 participants
Phase 4 N=64 Assessing Success of MTA and Pre-mixed Bioceramic in Mature Teeth With Irreversible Pulpitis With Full Pulpotomy.
Pulpitis - Irreversible
Primary: Clinical Success at 6 Months — 27; 30 Participants
N/A N=30 A Pilot Study to Assess Nominal Versus Controlled Stimuli on Dentinal Hypersensitivity
Dentin Sensitivity
Primary: Change From Baseline for Visual Analog Scale - Cold Water — -22.93 Units on a scale
Phase 3 N=113 Clinical Efficacy of a Toothpaste in Providing Relief From the Pain of Dentinal Hypersensitivity
Dentine Hypersensitivity
Primary: Change From Baseline in Evaporative Air Sensitivity Pain Response on a Schiff Sensitivity Scale at Day 14 — -1.20; -0.37 Score on a scale — p=<0.0001
Phase 4 N=40 Buffered vs. Unbuffered Local Anesthesia in Mandibular Molars Diagnosed With Symptomatic Irreversible Pulpitis
Symptomatic Irreversible Pulpitis
Primary: VAS Scores as Measures of Profoundness of Pulpal Anesthesia — 3.1; 1.2 Score on a scale
N/A N=36 Encapsulated Mesenchymal Stem Cells for Dental Pulp Regeneration.
Periapical Periodontitis
Primary: Number of Participats Showing Efficacy (Functionality) — 18; 18 Participants
N/A N=101 Evaluation of Hyaluronic Acid Pulpotomies in Primary Molars
Pulpitis
Primary: Number of Teeth Sensitive to Percussion in 3 Groups — 7; 6; 3 teeth — p=>0.05
Phase 3 N=118 The Efficacy of a Dentifrice in Providing Relief From the Pain of Dentinal Hypersensitivity
Dentine Hypersensitivity
Primary: Mean Change From Baseline in Evaporative Air Sensitivity Pain Response on a Schiff Sensitivity Scale at Week 8 — -0.9; -0.5 Score on a scale — p=<0.0001
N/A N=194 Post-endodontic Pain Survey
Postoperative Pain · Endodontic Disease · Obturation
Primary: Visual Analogue Scale (VAS) — 4.06; 2.68; 2.41; 2.27 score on a scale
N/A N=70 RCT of Pulp Capping Over Carious Exposure in Adults
Carious Exposure · Human Permanent First and Second Molars · Mature Teeth
Primary: Survival of Capped Pulps — 842; 1201 Survival days — p=<0.01
N/A N=120 Exploratory Clinical Study to Investigate the Ability of an Experimental Combination Dentifrice to Protect Sensitive Teeth
Dentin Sensitivity
Primary: Mean Schiff Sensitivity Score (Average of the Two Selected Test Teeth) at Baseline (Day 0) — 2.43; 2.44; 2.44; 2.34 score on a scale
N/A N=135 Evaluate the Effectiveness of an Experimental Urethane Dimethacrylate Resin Based Dental Composite Material
Dental Caries · Restorative Material
Primary: Percent of Teeth With Anatomic Form Graded as A or B. — 42; 37; 40; 2 teeth — p=0.2552
N/A N=376 Pulp Capping With Two Different Agents
Dental Pulp Exposure
Primary: Tooth Survival — 158; 130 participants — p=.046
Phase 2 N=70 MTA/FS Pulpotomy for Vital Primary Incisors: A Randomized Controlled Trial
Dental Caries · Dental Pulp Exposure
Primary: Comparison of MTA/FS Pulpotomy Versus RCT Treated Incisors With Acceptable Radiographic Outcome at 12 Months Post-procedure. — .97; .92 Proportion of incisors — p=.15
N/A N=24 Dentine Tubule Occlusion Assessment in a Modified in Situ Model
Dentin Sensitivity
Primary: Change From Baseline in Mean Occlusion Scores After 8 Days Treatment Application — 4.38; 4.32; 4.36; 3.43 Score on a scale — p=0.5512
N/A N=263 A Study to Measure the Efficacy of a Toothpaste on Dentinal Hypersensitivity
Dentin Sensitivity
Primary: Thermo-evaporative (Schiff Air Blast) Stimuli — 2.188; 2.246; 1.268; 1.811 score on a scale — p=<0.001
N/A N=11 Rutgers Pilot for PREDICT- Patient LAB Test
SARS-CoV2 Infection
Primary: Patient Willingness to Participate in the Study — 30 percentage
N/A N=76 Clinical Trial NuSmile Crowns
Primary Dental Caries, Multisurface Origin (Diagnosis)
Primary: Fitting — 37; 42; 48; 3 Teeth
N/A N=120 Study to Evaluate the Effectiveness of Test Dentifrice in the Relief of Dentinal Hypersensitivity
Dentin Sensitivity
Primary: Adjusted Mean Change From Baseline in Schiff Sensitivity Score at Week 12 (Test Dentifrice Versus [vs] Negative Control Dentifrice) — -1.19; -0.44 score on a scale…
N/A N=32 Effects of Photobiomodulation on Postoperative Pain After Primary Endodontic Therapy in Molars With Symptomatic Apical Periodontitis
Postoperative Pain
Primary: Pain as Assessed by the Visual Analog Scale — 0; .33 score on a scale
Early Phase 1 N=46 Pain Management in Teeth With Reversible Pulpitis
Reversible Pulpitis · Ibuprofen
Primary: Change in Pain Intensity From Baseline (Pre-Operative) to Immediately During the Procedure (Day 0), Measured by the Visual Analogue Scale (VAS) — 5.05; 0.64 score on a…
N/A N=60 Evaluation of the Dental Vibe Injection Comfort System
Anesthesia, Local · Pain
Primary: VAS — 2.5; 2.3; 2.7; 4.2 score on a scale — p=0.001
Phase 2 N=134 Exploratory Study to Evaluate an Occlusion Based Dentifrice in Relief of Dentinal Hypersensitivity
Dentine Hypersensitivity
Primary: Change From Baseline in Evaporative Air Sensitivity Pain Response on Schiff Sensitivity Scale at Week 4 — -0.36; -0.43; -0.40; -0.45 Score on a scale — p=0.4553
Phase 2 N=202 Study of Diclofenac Capsules to Treat Dental Pain
Dental Pain
Primary: Total Patient Pain Relief Over 0 to 12 Hours. — 17.770; 16.893; 14.685; 5.486 units on a scale — p=<0.001
N/A N=192 Trial of Nano-hydroxyapatite-Containing Toothpastes for Relief of Dentin Hypersensitivity
Dentin Sensitivity
Primary: Measurement of Cold Air Stimulus — 71.4; 72.2; 71.9; 51.1 units on a scale
N/A N=22 A Clinical Study to Compare Professional Treatments for Dentinal Hypersensitivity
Dentinal Hypersensitivity
Primary: Change From Baseline Air Challenge — -0.55; -0.95 Units on a scale