N/A N=4,350 Reducing Diagnostic Errors in Primary Care Pediatrics (Project RedDE)
Diagnostic Errors
Primary: Number of Adolescents Diagnosed With Depression Seen in Well Child Visits — 233; 443 Participants — p=<0.0001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 3 N=402 Reducing Diagnostic Error to Improve Patient Safety in COPD and Asthma (REDEFINE Study)
COPD Asthma
Primary: Total Number of Healthcare Visits — 111; 76; 119; 93 Participants
N/A N=46 Measuring and Improving the Safety of Test Result Follow-Up
Lung Cancer · Breast Cancer · Colon Cancer
Primary: Trigger Outcome — 67.0; 65.9; 78.6; 78.1 percentage of abnormal tests w/ followup
N/A N=1,256 Effectiveness of Electronic Health Record-Based Interventions for Improving Follow-Up in Primary Care
Colon Cancer · Lung Cancer · Prostate Cancer
Primary: Differences in Time to Documented Follow-up of a Red Flag Suggestive of Cancer — 104; 200; 144; 192 Days — p=<0.05
N/A N=541 Assessment of Acute Disease to Reduce Imaging Costs
Acute Coronary Syndrome · Pulmonary Embolism
Primary: Efficiency--Mean Cost of Care — 3933; 2761 US Dollars
N/A N=5,325 Digital Detection of Dementia (D Cubed) Studies: D2
Alzheimer Disease and Related Dementias (ADRD)
Primary: 12-Month Cumulative Incidence of ADRD Diagnoses — 213; 134; 355 Number of new ADRD cases — p=0.006
N/A N=214 Precision Diagnosis of Acute Infectious Diseases; Neuroinflammatory Cohort
Encephalitis · Meningitis
Primary: Total Number of Cases With at Least One Provider Response — 98; 58 cases
N/A N=604 Diagnostic Tools to Establish the Presence and Severity of Peripheral Arterial Disease in People With Diabetes
Diabetic Foot · Peripheral Arterial Disease · Diabetic Foot Ulcer
Primary: Diagnostic Accuracy — 36; 42; 55; 41 percentage
N/A N=3,000 Diagnostic Accuracy of Electrocardiogram for Acute Coronary Occlusion Resulting in Myocardial Infarction
Myocardial Infarction · Acute Coronary Syndrome · Coronary Artery Disease
Primary: The Sensitivity and Specificity of ECG for Acute Coronary Occlusion. — 767; 282; 16 Participants
N/A N=452 Integrating Contextual Factors Into Clinical Decision Support
Medical Errors · Decision Support Systems, Clinical · Diagnostic Errors
Primary: Resolution of Contextual Red Flags — 116; 240; 83; 99 Red flags — p=.91
N/A N=203 The Place of Imaging and Microbiology in the Diagnosis of Pneumonia in the Elderly
Pneumonia
Primary: Number of Patients With Modified Diagnosis Probability After Low Dose CT (LDCT) — 10; 3; 4; 34 Participants
N/A N=109 Trial of Simulation-based Mastery Learning to Communicate Diagnostic Uncertainty
Uncertainty · Communication Research · Emergency Medicine
Primary: % of Residents Who Pass the UCC at the T2 Assessment — 29; 2 Participants
N/A N=194 Rapid Diagnostics for Upper Respiratory Infections in the Emergency Department
Respiratory Tract Infections · Influenza, Human · Common Cold
Primary: Proportion of Patients Receiving Antibiotics or a Prescription for Antibiotics in the ED — 20; 33 Participants
N/A N=9 Smell, Voice and Nasal Swabs as Markers for Neuro-degenerative Disorders
Alzheimer Disease · Neurodegenerative Diseases
Primary: Alpha-synuclein Levels From Nasal Swabs
N/A N=100 Pathway to Detection & Differentiation of Delirium & Dementia in the Emergency Department
Cognitive Impairment · Emergency Care · Dementia
Primary: Percentage of Patients With Confirmed Delirium or Dementia — 30.8 percentage of participants
N/A N=498 Delirium in the Emergency Department: Novel Screening
Delirium
Primary: Delirium — 98.0; 56.2; 56.2; 54.8 percent
N/A N=110 Diagnostic Accuracy of Handheld vs Traditional Ultrasound
Image, Body
Primary: Diagnostic Accuracy — 53; 56 Participants
N/A N=723 Clinical Predictors for Venous Thromboembolism in Patients With a History of Thrombosis (PREDICTORS)
Thromboembolic Disease Recurrent · Deep Vein Thrombosis · Pulmonary Embolism
Primary: Validation of the Wells DVT Clinical Decision Rule — 67; 186; 148; 4 Participants
N/A N=4,892 Ventilator-associated Pneumonia (VAP) Diagnostic Stewardship Trial
VAP - Ventilator Associated Pneumonia
Primary: Total Number of Deaths in the Pre vs Post-intervention Time Periods Among Study Participants Per 1000 Mechanically Ventilated Patient Days — 72; 73 Deaths per 1000…
N/A N=394 Urine Trypsinogen 2 Dipstick for the Early Detection of Post-ERCP Pancreatitis
Post-ERCP Acute Pancreatitis
Primary: Sensitivity and Specificity of Urine Trypsinogen-2 Dipstick Testing for the Diagnosis of Post-ERCP Pancreatitis — 11.1; 91; 4.4; 96.5 percentage of participants
N/A N=73 Effect of Sedation on Diagnostic Injections
Sacroiliac Joint Pain · Sympathetically Maintained Pain
Primary: Pain Score — 2.2; 3.4 units on a scale
N/A N=165 Validation of a Diagnostic Algorithm of Giant Cell Arteritis
Giant Cell Arteritis
Primary: Number of CDU False-positive Patients — 73; 63; 0; 29 Participants
N/A N=89 (MIST1)-Part 1: Assessment & Feasibility of Post-Symptoms Evaluation
Patient Safety · Manipulation, Spinal
Primary: Number of Patient Encounters That Report a New or Worsening Symptom — 8 Participants
N/A N=33 Systematic Pediatric Assessment of Rome Criteria (SPARC)
Functional Gastrointestinal Disorders
Primary: Resolution of Symptoms From Initial Rome IV Diagnosis at 3 Months Using an Age-appropriate Rome IV Questionnaire. Number of Participants Who no Longer Meet Rome IV…
N/A N=105 Randomized Investigation of Chest Pain Diagnostic Strategies
Acute Coronary Syndrome · Chest Pain
Primary: The Composite of Revascularization, Re-hospitalization, and Recurrent Cardiac Testing Through 90 Days. — 7; 20 participants
N/A N=135 Diagnostics in the Leg Ulcer Pathway
Venous Leg Ulcer
Primary: Primary Care Practitioners and the Management of Venous Leg Ulcers. — 50; 34; 45 Participants
N/A N=328 Diagnostic Accuracy of "Three Rings Vulvoscopy" for Detection of Vulvar Dermatosis
Lichen Sclerosus · Lichen Planus · Lichen Simplex Chronicus
Primary: Diagnostic Accuracy of "Three Rings Vulvoscopy" by the "Vulvoscopy Index" for Detection of Vulvar Dermatosis — 72; 0; 10; 246 Participants — p=0.6108
N/A N=2,000 Primary Diagnosis Study for Validation of Hamamatsu NanoZoomer S360MD Digital Slide Scanner System
Pathology
Primary: Major Discordance Rate — 3.5; 3.1 Percentage of Major Discordances
N/A N=16 Differential Diagnosis for the Causes of Subclavian Steal for Patients With Vascular Access in the Forearm
Subclavian Steal
Primary: Change of Subclavian Flow to Normal Flow Pattern During Cuff Test — 0; 2 participants
N/A N=86 Diagnostic Yield of an Ambulatory Patch Monitor in Unexplained Emergency Department Syncope: A Pilot Study (PATCH-ED)
Syncope
Primary: Number of Ambulatory Patch Monitor Participants Having Significant Symptomatic Arrhythmia — 9 Participants