N/A N=72 Balloon Sinus Dilation In Office or OR
Chronic Sinusitis
Primary: Mean Intra-patient Change in SNOT-20 Score at 24 Weeks Post-procedure Compared to Baseline — -1.25; -1.35 scores on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=389 Long-term Control in Rhinosinusitis After Functional Endoscopic Sinus Surgery (FESS)
Condition of Patient 3 Years After FESS-operation
Primary: Control Status of Patients With Rhinosinusitis — 19.5; 36.8; 43.7 percentage of participants
N/A N=50 A Clinical Evaluation of the Sinexus Intranasal Splint Following Functional Endoscopic Sinus Surgery in Patients With Chronic Rhinosinusitis
Chronic Sinusitis
Primary: Device Success Rate — 14; 76; 10 ethmoid sinuses
N/A N=14 Study to Evaluate the Safety and Initial Effectiveness of the Sinusway™ for Endoscopy of Sinuses in Conjunction With BSD
Sinusitis
Primary: Number of Adverse Device Effects — 0 events
N/A N=50 Clinical Evaluation of the Steroid-Eluting Sinexus Intranasal Splint When Used Following Functional Endoscopic Sinus Surgery (FESS) in Patients With Chronic Sinusitis
Chronic Sinusitis
Primary: Safety as Determined by the Frequency of Serious Adverse Local Tissue Response (SALT) — 6 Number of Sinuses
N/A N=33 Intraoperative Bleeding During Endoscopic Sinus Surgery
Blood Loss
Primary: Estimated Blood Loss — 78.5; 80.3 mL/h — p=0.937
N/A N=151 Randomized Evaluation of Maxillary Antrostomy Versus Ostial Dilation Efficacy Through Long-Term Follow-Up
Chronic Sinusitis
Primary: Sinus Symptom Improvement — -1.59; -1.60; 0.88; 0.88 units on a scale — p=<0.001
Phase 4 N=72 Total Intravenous Anesthesia in Sinus Surgery
Advanced Chronic Rhinosinusitis
Primary: Intraoperative Visual Field Assessment — 3.3; 4.3; 3.3; 4.2 units on a scale
Phase 4 N=118 Pain Control Following Sinus Surgery
Sinusitis · Opioid Use · Opioid Abuse
Primary: Pain Severity — 12.4; 8.5 units on a scale
N/A N=25 Study for the Management of Pediatric Chronic Rhinosinusitis With or Without Balloon Sinuplasty
Rhinitis + Sinusitis, Pediatric Chronic Rhinosinusitis
Primary: Quality of Life (QoL) Outcomes Between Adenoidectomy + Maxillary Sinus Irrigation With or Without the Use of Balloon Dilation or Maxillary Sinus Ostia. — 2.48; 2.5…
Phase 2 N=3 A Clinical Trial of Endoscopic Surgery Followed by Chemotherapy and Proton Radiation for the Treatment of Tumors in the Sinus and Nasal Passages
Paranasal Sinus Cancer · Nasal Cavity Tumor · Nasal Cavity Adenocarcinoma
Primary: Local Control Assessment of Unresectable Paranasal Sinus and Nasal Cavity Tumors
Phase 4 N=80 Effects of Adrenaline Infiltration on Surgical Field of View in Endoscopic Sinus Surgery
Intraoperative Bleeding
Primary: Surgical Field Grading Score — 3.54; 3.23 score on a scale — p=0.77
N/A N=187 Efficacy of Macrolide and Glucocorticoid in the Treatment of Chronic Rhinosinusitis After Endoscopic Sinus Surgery
Chronic Rhinosinusitis · Endoscopic Sinus Surgery
Primary: Total Subjective Symptoms Visual Analog Scores (VAS) — 20.4; 20.7; 9.7; 8.9 score on a scale
Phase 4 N=53 Effectiveness of Mometasone Nasal Irrigation for Chronic Rhinosinusitis
Chronic Rhinosinusitis (Diagnosis) · Allergic Rhinosinusitis · Chronic Eosinophilic Rhinosinusitis
Primary: Change in Sino-Nasal Outcome Test Scores (SNOT-22) — 23.18; 17.7 score on a scale
N/A N=37 The Efficacy of MEDIHONEY® for Chronic Rhinosinusitis With Nasal Polyposis After Functional Endoscopic Sinus Surgery
Chronic Sinusitis · Nasal Polyposis
Primary: Change in Lund-Kennedy Endoscopic Scores — -8.0; -1.5; -6.9 score on a scale
N/A N=82 Trans-Nasal Maxillary Multi-Sinus Balloon Dilation Study
Sinusitis
Primary: Change in SNOT-20 Score — 2.3; 0.7 score on a scale — p=<0.0001
Phase 3 N=115 Clinical Evaluation to Confirm Safety and Efficacy of Sinuplasty in the Paranasal Sinuses (CLEAR)
Chronic Sinusitis
Primary: Number of Sinuses With Patency of Sinus Ostium After Sinuplasty — 247 Sinuses
Phase 3 N=105 A Clinical Evaluation of a Steroid-Coated Sinus Stent When Used Following Functional Endoscopic Sinus Surgery in Patients With Chronic Sinusitis
Chronic Sinusitis
Primary: Percentage of Sinuses Requiring Post-operative Intervention — 33.3; 46.9 percentage of sinuses — p=0.0280
N/A N=60 Efficacy of PuraSinus Versus Bioresorbable Nasal Dressings
Chronic Sinus Disease · Surgery
Primary: Pain During Debridement — 4; 5 Pain Score
N/A N=203 Optimization and Refinement of Technique in In-Office Sinus Dilation 2
Sinusitis
Primary: Mean Intra-patient Change in SNOT-20 Score — -1.16 Scores on a scale
Phase 1 N=36 Safety and Performance of the SinuSys Dilation System for Dilation of the Maxillary Sinus Ostium
Sinusitis
Primary: Patency of Treated Area — 95 percentage of ostia treated
Phase 3 N=42 Effect of Post-operative Ibuprofen After Surgery for Chronic Rhinosinusitis
Chronic Rhinosinusitis (Diagnosis)
Primary: Pain Visual Analogue Scale (VAS) — 3.3; 2.3 units on a scale — p=<0.05
N/A N=75 A Clinical Evaluation of the Intersect ENT Sinus Device (ASCEND)
Chronic Rhinosinusitis (Diagnosis)
Primary: Randomized Cohort: Difference in Patency Grade of FSO — 1.6; 1.5 score on a scale
N/A N=100 In-office Placement of the Propel Mini Sinus Implant in the Frontal Sinus Ostia
Chronic Sinusitis
Primary: Patency Rate — 38; 33 sinus sides — p=0.0391
Phase 4 N=56 Postoperative Pain and Functional Patient Outcomes After Functional Endoscopic Sinus Surgery
Pain, Postoperative
Primary: Postoperative Pain Assessed on Standard VAS Scale — 0.48; 1.12 units on a scale
N/A N=160 A Clinical Evaluation of PROPEL® Contour Sinus Implant
Chronic Rhinosinusitis (Diagnosis)
Primary: Difference in FSO Patency by Blinded Reviewer — 16.54; 12.36 mm^2 — p=0.059
Phase 4 N=89 Prophylactic Antibiotics After Functional Endoscopic Sinus Surgery: a Randomized, Double-blind Placebo Controlled Trial
Sinusitis
Primary: Sinonasal Outcome Test - 22 — 31.3; 31.0 score on a scale
Phase 2 N=24 Benralizumab Effect on Severe Chronic Rhinosinusitis With Eosinophilic Polyposis
Chronic Rhinosinusitis (Diagnosis) · Nasal Polyps · Eosinophilia
Primary: Change in Nasal Polyp Score — .9; .3 score on a scale
Phase 4 N=40 Comparing Blood Loss and Visualization After the Preoperative Use of Topical 0.05% Oxymetazoline Versus 1:1000 Epinephrine Prior to Endoscopic Sinus Surgery
Endoscopic Sinus Surgery · Nasal Polyps
Primary: Surgical Field Visualization During Sinus Surgery as Indicated by Score on Boezaart Grading Scale — 3; 2.55 score on a scale
N/A N=32 Comparison of Nasal Steroids After FESS in CRSwNP
Sinusitis · Nasal Polyps
Primary: SNOT-22 Scores — 31.5; 10.29; 15.88 units on a scale