N/A N=8 Mild Cognitive Impairment and Endurance Exercise in Parkinson's Disease
Parkinson Disease · Mild Cognitive Impairment
Primary: Mean Change in Cognitive Function — -0.6960; -0.6095; 0.6018; 0.6018 z-score
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=66 Study of the Long-term Effects of Exercise on Heath Indicators in Older People
Hypertension With Complications and Secondary Hypertension · Overweight and Obesity · Lipid Metabolism Disorders
Primary: Cardiovascular Disease Risk Factors — 3; 4; 5; 7 participants
N/A N=32 Physiologic Adaptations to Interval and Continuous Running at Low Volume and Vigorous Intensity Over 14-Weeks.
Exhaustion - Physiological
Primary: Relative Maximal Oxygen Uptake — 47.8; 50.9; 49.7; 51.7 mL/(kg*min) — p=< 0.05
N/A N=9 Exercise Mode and Acute Bone Resorption
Osteoporosis · Aging
Primary: C-telopeptide of Type I Collagen (CTX) Change — 0.09; 0.08 ng/mL
N/A N=33 Strength Training and Endurance Exercise for LIFE
HIV
Primary: Aerobic Capacity — 0.15; 0.02 Liters/minute
Early Phase 1 N=10 Influence of Edible Marijuana on Endurance Exercise Performance
Endurance Exercise
Primary: Comparison of Blood Lactate Levels During a 24 Minute Graded Standard Exercise Test (50 Watts, 100 Watts, and 150 Watts) to Placebo. — 0.9699; 1.1437; 1.26345; 1.3618…
Phase 2 N=26 EXTEND Exercise Trial
Non-metastatic, Hormone naïve Prostate Cancer
Primary: Change in VO2peak in Usual Care Versus Exercise Training Arms — -3.23; -0.92 mL/kg/min
N/A N=94 Gas Exchange Kinetics and Work Load During Exercise
Methods of Exercise in Children
Primary: Maximum Oxygen Uptake (VO2) Measurements During Exercise — 1.6; 2.8; 3.2; 1.7 L/min
N/A N=20 Sex Differences in Vascular Responses to Exercise
Aging
Primary: Change in FMD in Response to Chronic HIIT — 0.11; 0.57; 0.81; 0.10 % flow mediated dilation
Phase 3 N=89 The Effect of Indacaterol on Exercise Endurance in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease
Primary: Exercise Duration Time Assessed by Constant-load Cycle Ergometry at the End of Each Treatment Period — 586; 475 Seconds
Phase 3 N=157 Effect of Treatment BI 1744 CL (5 and 10 mcg) Versus Placebo on Exercise Endurance Time During Constant Work Rate Cycle Ergometry II
Pulmonary Disease, Chronic Obstructive
Primary: Adjusted Mean Endurance Time After 6 Weeks — 354.33; 396.31; 391.45 seconds — p=0.0018
Phase 4 N=20 Effect of Bronchodilation on Cycle vs Treadmill Exercise Endurance Time in COPD
Chronic Obstructive Pulmonary Disease
Primary: Exercise Endurance Time — 490; 333; 472; 362 seconds — p=< 0.05
Early Phase 1 N=30 Contribution of Endothelin-1 to Exercise Intolerance in Heart Failure
Heart Failure
Primary: Blood Flow — 300; 275 ml/min
N/A N=16 Effect of Exercise on the Human Skeletal Muscle Phosphoproteome
Skeletal Muscle Protein Synthesis
Primary: Change in Acute Muscle Protein Synthesis — 143; 123 percent change
N/A N=45 Exercise Therapy to Reduce Heart Failure Symptoms; Sorting Mechanisms of Benefit
Heart Failure
Primary: Oxygen Uptake (VO2) Peak — 1778.1; 1228.2; 1393.7; 1763.6 ML/KG/Min
N/A N=33 Exercise and the Receptor for Advanced Glycation End Products (RAGE)
Diabetes Mellitus, Type 2
Primary: Quantify the Percentage Change in Basal Circulating sRAGE After 12-weeks of Supervised Aerobic Exercise Training. — 24.5; 0.5 Percent Change in sRAGE
Phase 4 N=8 Impact of Erythropoietin on Hematological Adaptations and Physical Performance
Exercise-Induced Anemia · Physical Performance
Primary: Concentration of Hemoglobin — 1.46 g/dL
Phase 2 N=39 Evaluation of Cortisol Resistance in Young Sedentary and Endurance-Trained Men
Cortisol Resistance · Negative Feedback · ACTH
Primary: Proportion of Suppressors After Dexamethasone — 0; 1 Participants — p=0.4872
N/A N=14 Isoenergetic High Intensity Interval Training and Moderate Intensity Training in Adults With Type I Diabetes
Diabetes Mellitus, Type 1
Primary: Mean Energy Expenditure Between HIIT and MICT — 264.5; 225.5 kcal — p=0.010
N/A N=100 Exercise Intolerance in Elderly Patients With Diastolic Heart Failure
Heart Failure, Diastolic · Obesity
Primary: Exercise Capacity — 15.5; 15.5; 14.1; 16.6 ml/kg/min — p=<0.001
N/A N=136 Study of Exercise Training in Hypertrophic Cardiomyopathy
Cardiomyopathy, Hypertrophic
Primary: Change in Peak Oxygen Consumption (Peak VO2) — 1.35; 0.08 mL/kg/min
N/A N=119 Exercise for Brain Health in the Fight Against Alzheimer's Disease
Healthy Cognition
Primary: Rey Auditory Verbal Learning Test Sum of Trials 1-5 — 49.7; 47.6; 51.6; 49.4 Sum of words recalled Trials 1 to 5
N/A N=11 Exercise Training in Heart Failure: Changes in Cardiac Structure and Function
Heart Failure
Primary: Change in Left Ventricular Systolic Function. — .82; -1.90 percent LVEF — p=.14
Phase 3 N=151 Effect of Treatment BI 1744 CL (5 and 10 mcg) Versus Placebo on Exercise Endurance Time During Constant Work Rate Cycle Ergometry I
Pulmonary Disease, Chronic Obstructive
Primary: Adjusted Mean Endurance Time After 6 Weeks — 369.81; 421.58; 420.72 seconds — p=0.0002
N/A N=43 Effects of Aerobic Exercise in Parkinson's Disease
Parkinson Disease
Primary: Change in Aerobic Fitness — 1.56 ml/min/kg — p=<0.001
Early Phase 1 N=101 Dose Response Study of Aerobic Exercise in Older Adults
Alzheimer's Disease
Primary: Visuospatial Processing — -.02; .19; .08; .29 units on a scale
Phase 3 N=295 Effect on Exercise Endurance and Lung Hyperinflation of Tiotropium + Olodaterol in COPD Patients
Pulmonary Disease, Chronic Obstructive
Primary: Inspiratory Capacity at Rest Before Constant Work Rate Cycle Ergometry to Symptom Limitation at 75% Wcap — 2.440; 2.566; 2.571; 2.658 Litres — p=<0.0001
N/A N=30 Exercise Training for the Treatment of Generalized Anxiety Disorder
Generalized Anxiety Disorder
Primary: Generalized Anxiety Disorder (GAD) Remission as Measured by Anxiety Disorders Interview Schedule-Adult Version (ADIS-IV) Severity Ratings — 4; 6; 7 Participants
N/A N=88 Exercise Intolerance in Elderly Patients With HFpEF(Heart Failure With Preserved Ejection Fraction)
Heart Failure, Diastolic · Obesity
Primary: Peak Exercise Oxygen Consumption (VO2) — 1609; 1653 ml/min — p=0.21
N/A N=34 Exercise-induced Hypoalgesia After Comparative Forms of Exercise
Pain
Primary: Change in Pain Intensity Ratings (0-100 Pain Scale) — 33.5; 46.2; 40.2 scores on a scale