N/A N=60 EpiFaith Syringe for Epidural Space Detection
Epidural Localization
Primary: Success of Epidural Localization — 18; 30; 0; 0 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=11 Epidural Lavage Study for Lumbar Stenosis
Lumbar Spinal Stenosis
Primary: Visual Analogue Scale — 6.2; 5.0; 5.0; 0.8 score on a scale
Phase 4 N=400 Lumbar Epidural Steroid Injections for Spinal Stenosis Multicenter Randomized, Controlled Trial (LESS Trial)
Spinal Stenosis · Low Back Pain
Primary: Roland Morris — 11.8; 12.5 units on a scale
N/A N=80 Ultrasound-Guided Landmark and Epidural Site Pain
Back Pain · Epidural Analgesia, Obstetric
Primary: Epidural Pressure Sensitivity at Level of Epidural Insertion — 26.8; 26.8; 47.6 force (newtons/cm^2)
N/A N=92 Epidural Neuroplasty for the Treatment of Herniated Lumbar Disk
Herniated Lumbar Disc
Primary: Pain Assessed by Visual Analogue Scale — 5.63; 5.92 units on a scale
Phase 2 N=70 Intravenous(IV) vs. Erector Spinae Plane Blocks in Cardiac Surgery
Erector Spinae Plane Block · Pain Control · Post-Operative Pain, Chronic
Primary: Quantitate the Amount of Opioid Medication Required to Provide Pain Relief-Cumulative First 48 Hours — 80.2; 54.9 Morphine Milligram Equivalents
Phase 3 N=401 Corticosteroid Lumbar Epidural Analgesia for Radiculopathy
Lumbosacral Radicular Pain
Primary: Mean Change From Baseline (Day 1) to Week 4 in the Mean Numeric Pain Rating Scale (NPRS) Average Pain Score in the Affected Leg — -2.34; -1.16 Change in score on a scale…
Phase 2 N=74 Transforaminal Versus Lateralized Interlaminar Cervical Epidurals
Cervicogenic Upper Extremity Radiculopathy
Primary: Change in Pain Numerical Rating Scale (Averaged Over Past 24 Hours) — -3.38; -2.30 score on a scale — p=0.057
N/A N=20 Dispersal Pattern for Spine Injections (Gadolinium Contrast)
Cervical Radiculopathy
Primary: Injection Dispersal Patterns Measured (in cm) in the Superoinferior Directions on Post-injection MRI With a Calibrated Internal Measurement Software. — 14.73 cm
Phase 3 N=45 Bupivacaine With Epidural Volume Extension
Spinal Anesthesia · Epidural; Anesthesia
Primary: Time Until PACU Discharge in Minutes — 135; 50 minutes
Phase 2 N=356 Comparison of Loss of Resistance Techniques
Pain Relief
Primary: Success of Spinal Labor Analgesia From Combined Spinal Epidural — 163; 161 Participants — p=>.05
Phase 4 N=12 Distribution, Pharmacokinetics and Extent of Sensory Blockade in ESP Blocks
Distribution of Ropivacaine in Erector Spinae Plane Block
Primary: Area of Dermatomal Sensory Loss at 20 Min — 68.8; 167.5 cm^2
Phase 4 N=79 C7-T1 Epidural Steroid Injections Versus Targeted Injection for Treatment of Cervical Radicular Pain
Radicular; Neuropathic, Cervical · Neck Pain
Primary: Percentage of Participants With ≥50% Pain Reduction on the Numeric Rating Score (NRS) for Pain — 60; 72 percentage of participants — p=0.23
N/A N=50 Accuracy of Manual Palpation vs Ultrasound for Spinal Anesthesia
Anesthesia, Local · Infant Conditions
Primary: Intended Interspace — 1; 24; 25 Participants
N/A N=116 Perioperative Intravenous Lidocaine or Epidural Anesthesia on Outcomes in Complex Spine Surgery
Spine Surgery
Primary: Mean Pain Scores — 4.4; 5.3 verbal response scores — p=<0.001
N/A N=100 Fluoroscopy-guided Versus Traditional Placement of Epidural Catheters
Pain, Postoperative · Pain, Chronic
Primary: Intravenous Pain Medication — 63; 66 milligrams
N/A N=120 CompuFlo Thoracic Epidural Study
Thoracic Epidural Anesthesia
Primary: Number of Participants With Successful Thoracic Epidural Catheter Placement — 52; 58 Participants
N/A N=116 Compare Epidural vs. Lumbar Plexus Analgesia After Hip Arthroplasty
Arthropathy of Hip
Primary: Opiate Consumption — 64.8; 81.3 Opiate Consumption (IV MME)
Phase 2 N=58 Combined Spinal-Epidural Temperature and Duration of Action
Pain
Primary: Time — 74; 81 minutes
N/A N=160 A Novel Way to Estimate Epidural Depth in Morbidly Obese Parturient
Obesity
Primary: Correlation Between Actual Epidural Needle Depth (ND) and Estimated Epidural Depth (Est-D) — 0.905; 0.899 correlation coefficient — p=< 0.05
Phase 4 N=46 Erector Spinae Plane Block Versus Conventional Analgesia in Complex Spine Surgery
Opioid Use · Pain, Postoperative
Primary: Intraoperative and Postoperative Opioid Consumption — 191; 139.4 MME/day
Phase 4 N=38 Study of Epidural Steroid Injection (ESI) Versus Minimally Invasive Lumbar Decompression (Mild®) in Patients With Symptomatic Lumbar Central Canal Stenosis
Lumbar Spinal Stenosis
Primary: Mean Change in VAS — 2.52; 0.06 units on a scale — p=<0.05
Phase 4 N=42 ED90 for Hyperbaric Bupivacaine in Super Obese Parturients
Obesity, Morbid · Spinal Anesthesia · Cesarean Delivery
Primary: Number of Participants With Successful Blocks for Induction (Success Induction) — 1; 3; 27; 11 Participants
Phase 4 N=141 DPE Technique in Labor Epidural for Morbidly Obese Women
Morbid Obesity · Labor Pain
Primary: Number of Participants Who Required Asymmetric Block, Top-up Interventions, Catheter Adjustments, Replacement of Epidural Catheter, or Failure of Block Requiring…
N/A N=170 Optimizing Dose of Bupivacaine in Combined Spinal Epidurals To Reduce Side Effects
Pregnancy
Primary: Maternal Blood Pressure — 78.2; 79.58; 80.52 mm/Hg
N/A N=165 Long Term Outcomes of Lumbar Epidural Steroid Injections for Spinal Stenosis
Lumbar Spinal Stenosis
Primary: Utilization of ESI — 3.6; 3.3 number of ESI between 18-24 months
N/A N=61 CSE v. Epidural for Postpartum Depression
Depression, Postpartum · Labor Pain
Primary: Edinburgh Postnatal Depression Score (EPDS) — 4.23; 4.71 score on a scale — p=0.7463
Phase 3 N=84 A 3-arm Multi-center, Randomized Controlled Study Comparing Transforaminal Corticosteroid, Transforaminal Etanercept and Transforaminal Saline for Lumbosacral Radiculopathy
Lumbosacral Radiculopathy
Primary: Numerical Rating Leg Pain Score — 2.54; 3.56; 3.78 units on a scale
N/A N=36 A Prospective Observational Study of Epidural Pressures During Caudal Epidural in the Pediatric Population
Anesthesia, Caudal
Primary: Pressure in the Caudal Epidural Space — 192.5 mmHg
N/A N=18 Use of Ultrasound Guidance to Assist With Labor Epidural Placement in Patients With a BMI ≥40
Labor Pain
Primary: Total Time Required for Epidural Catheter Placement — 6.1; 11.0 Minutes