Phase 4 N=13 Fracture (FX) Improvement With Teriparatide: FiX-IT Study
Osteoporosis · Atypical Femoral Fracture
Primary: Radiologic Evidence of Bone Healing — 12.6; 11.2; 15.4; 13.2 units on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=20 Reduction and Fixation of Metatarsal Neck Fracture by Metaizeau's Technique
Displaced Metatarsal Neck Fracture
Primary: Time of Union — 5.8 weeks
N/A N=30 Wrist Fracture Evaluation With a Desktop Orthopedic Tomosynthesis System
Fracture
Primary: Sensitivity — 96.7 percent of scans with a fracture
N/A N=60 Fixation of Unstable Distal Radius Fractures
Distal Radius Fractures
Primary: Average Difference Between Michigan Hand Outcomes Questionnaire Scores — 85.2; 91.8 units on a scale
N/A N=216 Randomized Trial of Casting Techniques for Displaced Forearm Fractures
Displaced Forearm Fractures
Primary: Loss of Radius Fracture Reduction — 35; 35; 66; 66 participants — p=1.00
Phase 3 N=122 Effect of Teriparatide on Hip Fracture Healing
Femur Neck Fracture
Primary: Percentage of Participants With No Revision Surgery at 12 Months After Internal Fixation of a Low-Trauma Femoral Neck Fracture — 87; 86 percentage of participants
N/A N=20 Orthopaedic Treatment Proximal Humeral Fractures
Proximal Humeral Fracture
Primary: Constant Scale Evaluation at 3 Months and 12 Months From the Date of Trauma — 40.1; 51.8 units on a scale — p=<0.01
Phase 3 N=39 Second Study of the Effect of Teriparatide on Hip Fracture Healing
Femur Neck Fracture
Primary: Percentage of Participants With No Revision Surgery at 12 Months After Internal Fixation of a Low-Trauma Femoral Neck Fracture — 74; 93 Percentage of participants
Phase 4 N=1,366 VERtebral Fracture Treatment Comparisons in Osteoporotic Women
Postmenopausal Osteoporosis
Primary: Proportion of Participants With New Vertebral Fractures — 28; 64 Participants (with at least one event) — p=0.000094
N/A N=156 A Multicenter Randomized Trial Comparing IM Nails and Plate Fixation in Distal Femur Fractures
Femoral Fractures
Primary: EQ-5D — 69.23; 72.81; 74.24; 73.04 units on a scale
Phase 3 N=131 Vertebroplasty for the Treatment of Fractures Due to Osteoporosis
Spinal Fractures · Osteoporosis
Primary: Back-specific Functional Status Using Roland-Morris Disability Questionnaire (RDQ) Scale at 1 Month — 12.0; 13.0 units on a scale — p=0.49
Phase 2 N=11 Proof-of-concept Study With NVDX3 for Treatment of Distal Radius Fractures.
Distal Radius Fractures
Primary: Safety: Serious Treatment-emergent Adverse Events (TEAEs) and NVDX3-related TEAEs — 1; 1 Participants
N/A N=66 Skeletal Versus Cutaneous Traction For Treatment of Femur Fractures
Femur Fracture
Primary: Difference in the Two Groups in Regards to Resident Time. — 24; 57 minutes
Phase 3 N=120 Non-bridging Fixator Versus Percutaneous Pinning for Distal Radius Fractures
Radius Fractures
Primary: The Grip Strength — 98.3; 62.6 Percentage of opposite side — p=<0.05
Phase 2 N=402 Study of Romosozumab (AMG 785) in Tibial Diaphyseal Fractures Status Post Intramedullary Nailing
Fracture Healing
Primary: Time to Radiographic Healing — 16.4; 18.6; 18.3; 18.2 weeks — p=0.3598
Phase 2 N=332 Study To Assess FRacTure Healing With SclerosTin Antibody - Hip
Fracture Healing
Primary: Timed-Up-and-Go (TUG) Over Week 6 Through Week 20 — 54.1; 41.0; 47.2; 53.3 seconds — p=0.1983
N/A N=81 Safety and Efficacy Study of Treatment of Pathological Fractures in Humerus
Humerus Fracture Metastatic Bone Disease
Primary: Change in Pain — -52.7 units on a scale — p=0.615
Phase 2 N=22 Phase 1/2a Study on Allogeneic Osteoblastic Cells Implantation in Delayed-Union Fractures
Long Bone Delayed-Union Fracture
Primary: Percentage of Responders at 6 Months (Efficacy of ALLOB) — 100 percent of patients
Phase 2 N=35 PTH(1-34) and Pelvic Fracture Healing - a Randomized Controlled Trial
Osteoporotic Fractures
Primary: Number of Participants With Evidence of Cortical Bridging for Fracture Healing — 9; 8 Participants
N/A N=62 Cast Immobilization for Non-Displaced Scaphoid Fractures
Non-displaced Scaphoid Fractures
Primary: Extent of Union — 70; 85 percentage of union
Phase 3 N=1,262 Denosumab Fracture Intervention Randomized Placebo Controlled Trial in Japanese Patients With Osteoporosis
Osteoporosis
Primary: Incidence of New or Worsening Vertebral Fractures in Osteoporotic Subjects Treated With Denosumab Compared to Placebo — 3.6; 10.3; 7.2 Vertebral fractures — p=0.0001
N/A N=99 A Multicenter Randomized Trial Comparing IM Nails and Plate Fixation in Proximal Tibial Fractures
Tibial Fractures
Primary: Participants' Quality of Life at 3 Months — 0.60; 0.59 score on a scale
N/A N=1,108 Using Alternative Implants for the Surgical Treatment of Hip Fractures (The FAITH Study)
Femoral Neck Fractures
Primary: Revision Surgery — 107; 117 Participants
N/A N=9 Computed Tomography for Evaluating Supination-external Rotation Type Ankle Fractures
Supination-external Rotation Ankle Fractures
Primary: Medial Clear Space Distance in the Ankle Joint — 1.41 mm
N/A N=11 Platelet Rich Plasma Injection in Pilon Fractures
Fracture
Primary: Intra-articular Inflammatory Biomarkers at the Time of Definitive Fixation — 54.89; 163.01; 2479.17; 2511.32 pg/ml
N/A N=36 chronOS Inject in Proximal Tibial Fractures
Closed Proximal Tibial Fracture Schatzker I - VI · Closed Proximal Tibial Fracture AO-OTA 41 · Closed Proximal Tibial Fracture AO-OTA 42
Primary: Fracture Union — 27; 2 participants
Phase 3 N=16 Prospective Biomarkers of Bone Metabolism in Hemophilia A
Hemophilia · Bone Disease
Primary: Bone Biomarker Density (BMD) — -0.74; -0.16; -0.16 Z-Score
N/A N=141 Build Better Bones With Exercise
Osteoporotic Fractures · Spinal Fractures
Primary: Feasibility of Recruitment and Retention — 66; 64 Participants
N/A N=23 Taping to Control Edema in Patients With Forearm Plaster for Wrist Fracture.
Edema Arm · Fracture; Wrist
Primary: Thumb Circumference — -0.2; 0 cm
N/A N=53 Mobilizing Evidence Into Action to Improve Outcomes of Vulnerable Seniors
Hip Fractures · Femoral Fractures
Primary: Short Physical Performance Battery — 8.24; 9.08 score on a scale